University of Stirling

About: University of Stirling is a education organization based out in Stirling, Stirling, United Kingdom. It is known for research contribution in the topics: Population & Polyunsaturated fatty acid. The organization has 7722 authors who have published 20549 publications receiving 732940 citations. The organization is also known as: Stirling University.

Low‐ to high‐fidelity simulation – a continuum of medical education?

Abstract: Context Changes in medical training and culture have reduced the acceptability of the traditional apprenticeship style training in medicine and influenced the growth of clinical skills training. Simulation is an educational technique that allows interactive, and at times immersive, activity by recreating all or part of a clinical experience without exposing patients to the associated risks. The number and range of commercially available technologies used in simulation for education of health care professionals is growing exponentially. These range from simple part-task training models to highly sophisticated computer driven models. Aim This paper will review the range of currently available simulators and the educational processes that underpin simulation training. The use of different levels of simulation in a continuum of training will be discussed. Although simulation is relatively new to medicine, simulators have been used extensively for training and assessment in many other domains, most notably the aviation industry. Some parallels and differences will be highlighted.

The genomic substrate for adaptive radiation in African cichlid fish

Abstract: Cichlid fishes are famous for large, diverse and replicated adaptive radiations in the Great Lakes of East Africa. To understand the molecular mechanisms underlying cichlid phenotypic diversity, we sequenced the genomes and transcriptomes of five lineages of African cichlids: the Nile tilapia (Oreochromis niloticus), an ancestral lineage with low diversity; and four members of the East African lineage: Neolamprologus brichardi/pulcher (older radiation, Lake Tanganyika), Metriaclima zebra (recent radiation, Lake Malawi), Pundamilia nyererei (very recent radiation, Lake Victoria), and Astatotilapia burtoni (riverine species around Lake Tanganyika). We found an excess of gene duplications in the East African lineage compared to tilapia and other teleosts, an abundance of non-coding element divergence, accelerated coding sequence evolution, expression divergence associated with transposable element insertions, and regulation by novel microRNAs. In addition, we analysed sequence data from sixty individuals representing six closely related species from Lake Victoria, and show genome-wide diversifying selection on coding and regulatory variants, some of which were recruited from ancient polymorphisms. We conclude that a number of molecular mechanisms shaped East African cichlid genomes, and that amassing of standing variation during periods of relaxed purifying selection may have been important in facilitating subsequent evolutionary diversification.

Global assessment of experimental climate warming on tundra vegetation: heterogeneity over space and time.

Abstract: 35 Abstract Understanding the sensitivity of tundra vegetation to climate warming is critical to forecasting future biodiversity and vegetation feedbacks to climate. In situ warming experiments accelerate climate change on a small scale to forecast responses of local plant communities. Limitations of this approach include the apparent site-specificity of results and uncertainty about the power of short-term studies to anticipate longer term change. We address these issues with a synthesis of 61 experimental warming studies, of up to 20 years duration, in tundra sites worldwide. The response of plant groups to warming often differed with ambient summer temperature, soil moisture and experimental duration. Shrubs increased with warming only where ambient temperature was high, whereas graminoids increased primarily in the coldest study sites. Linear increases in effect size over time were frequently observed. There was little indication of saturating or accelerating effects, as would be predicted if negative or positive vegetation feedbacks were common. These results indicate that tundra vegetation exhibits strong regional variation in response to warming, and that in vulnerable regions, cumulative effects of long-term warming on tundra vegetation - and associated ecosystem consequences - have the potential to be much greater than we have observed to date.

What minds have in common is space : Spatial mechanisms serving joint visual attention in infancy

Abstract: A series of experiments is reported which show that three successive mechanisms are involved in the first 18 months of life in ‘looking where someone else is looking’. The earliest ‘ecological’ mechanism enables the infant to detect the direction of the adult's visual gaze within the baby's visual field but the mother's signal alone does not allow the precise localization of the target. Joint attention to the same physical object also depends on the intrinsic, attention-capturing properties of the object in the environment. By about 12 months, we have evidence for presence of a new ‘geometric’ mechanism. The infant extrapolates from the orientation of the mother's head and eyes, the intersection of the mother's line of sight within a relatively precise zone of the infant's own visual space. A third ‘representational’ mechanism emerges between 12 and 18 months, with an extension of joint reference to places outside the infant's visual field. None of these mechanisms require the infant to have a theory that others have minds; rather the perceptual systems of different observers ‘meet’ in encountering the same objects and events in the world. Such a ‘realist’ basis for interpersonal knowledge may offer an alternative starting point for development of intrapersonal knowledge, rather than the view that mental events can only be known by construction of a theory.