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Institution

University of Stuttgart

EducationStuttgart, Germany
About: University of Stuttgart is a education organization based out in Stuttgart, Germany. It is known for research contribution in the topics: Laser & Finite element method. The organization has 27715 authors who have published 56370 publications receiving 1363382 citations. The organization is also known as: Universität Stuttgart.


Papers
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Journal ArticleDOI
TL;DR: This work presents a dynamic model, which, for the first time, links the sugar transport system (i.e., phosphotransferase system [PTS]) with the reactions of glycolysis and the pentose-phosphate pathway, and offers the possibility of studying important questions regarding the stability and control of metabolic fluxes.
Abstract: Application of metabolic engineering principles to the rational design of microbial production processes crucially depends on the ability to describe quantitatively the systemic behavior of the central carbon metabolism to redirect carbon fluxes to the product-forming pathways. Despite the importance for several production processes, development of an essential dynamic model for central carbon metabolism of Escherichia coli has been severely hampered by the current lack of kinetic information on the dynamics of the metabolic reactions. Here we present the design and experimental validation of such a dynamic model, which, for the first time, links the sugar transport system (i.e., phosphotransferase system [PTS]) with the reactions of glycolysis and the pentose-phosphate pathway. Experimental observations of intracellular concentrations of metabolites and cometabolites at transient conditions are used to validate the structure of the model and to estimate the kinetic parameters. Further analysis of the detailed characteristics of the system offers the possibility of studying important questions regarding the stability and control of metabolic fluxes. © 2002 Wiley Periodicals, Inc. Biotechnol Bioeng 79: 53–73; 2002.

574 citations

Journal ArticleDOI
TL;DR: The isolation of yeast mutants defective in autophagocytosis (aut mutants) using a rapid colony screening procedure, and the elucidation of its mechanisms via genetic and molecular biological investigations are reported.

573 citations

Journal ArticleDOI
17 Oct 2008-Science
TL;DR: Room-temperature ionic liquids with the tris(pentafluoroethyl)trifluorophosphate anion in contact with a charged sapphire substrate were investigated with submolecular resolution and showed strong interfacial layering, akin to the charge inversion effect.
Abstract: Room-temperature ionic liquids (RTILs) are promising candidates for a broad range of "green" applications, for which their interaction with solid surfaces plays a crucial role. In this high-energy x-ray reflectivity study, the temperature-dependent structures of three ionic liquids with the tris(pentafluoroethyl)trifluorophosphate anion in contact with a charged sapphire substrate were investigated with submolecular resolution. All three RTILs show strong interfacial layering, starting with a cation layer at the substrate and decaying exponentially into the bulk liquid. The observed decay length and layering period point to an interfacial ordering mechanism, akin to the charge inversion effect, which is suggested to originate from strong correlations between the unscreened ions. The observed layering is expected to be a generic feature of RTILs at charged interfaces.

573 citations

Journal ArticleDOI
TL;DR: In this paper, the authors highlight the progress in three leading material platforms: diamond, silicon carbide and atomically thin semiconductors, with a focus on applications in quantum networks.
Abstract: A central goal in quantum optics and quantum information science is the development of quantum networks to generate entanglement between distributed quantum memories. Experimental progress relies on the quality and efficiency of the light–matter quantum interface connecting the quantum states of photons to internal states of quantum emitters. Quantum emitters in solids, which have properties resembling those of atoms and ions, offer an opportunity for realizing light–matter quantum interfaces in scalable and compact hardware. These quantum emitters require a material platform that enables stable spin and optical properties, as well as a robust manufacturing of quantum photonic circuits. Because no emitter system is yet perfect and different applications may require different properties, several light–matter quantum interfaces are being developed in various platforms. This Review highlights the progress in three leading material platforms: diamond, silicon carbide and atomically thin semiconductors. Atom-like quantum emitters in solids have emerged as promising building blocks for quantum information processing. In this Review, recent advances in three leading material platforms—diamond, silicon carbide and atomically thin semiconductors—are summarized, with a focus on applications in quantum networks

572 citations

Journal ArticleDOI
TL;DR: The predicted optimal sequences from position −3 to +2 for PKCα, - βI, -βII, -γ, -δ, and -η were very similar to the endogenous pseudosubstrate sequences of these PKC isozymes, indicating that these core regions may be important to the binding of corresponding substrate peptides.

572 citations


Authors

Showing all 28043 results

NameH-indexPapersCitations
Yi Chen2174342293080
Robert J. Lefkowitz214860147995
Michael Kramer1671713127224
Andrew G. Clark140823123333
Stephen D. Walter11251357012
Fedor Jelezko10341342616
Ulrich Gösele10260346223
Dirk Helbing10164256810
Ioan Pop101137047540
Niyazi Serdar Sariciftci9959154055
Matthias Komm9983243275
Hans-Joachim Werner9831748508
Richard R. Ernst9635253100
Xiaoming Sun9638247153
Feng Chen95213853881
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023147
2022482
20212,588
20202,646
20192,654
20182,525