Showing papers by "University of Tennessee Health Science Center published in 1973"
TL;DR: The most frequent findings were alteration of consciousness, headache, and elevated peripheral white blood cell count; fever, hemiparesis, seizures, neck stiffness, nausea and vomiting, and papilledema were less common.
Abstract: ✓ The records of 88 patients with intraparenchymal brain abscess treated during 1946–1971 were reviewed The incidence of brain abscess did not decline significantly during this period The overall mortality rate was 364%, and the operative mortality rate 291% The most frequent findings were alteration of consciousness, headache, and elevated peripheral white blood cell count; fever, hemiparesis, seizures, neck stiffness, nausea and vomiting, and papilledema were less common Lumbar puncture was a definite threat to the patient with a brain abscess Ventriculography appeared slightly superior to angiography in accurately localizing the site of the abscess There was a close correlation between the preoperative level of consciousness and the operative mortality rate With the aid of Thorotrast, simple aspiration or drainage was superior to excision; when Thorotrast was not used, excision produced better results The rate of postoperative seizure disorder was similar regardless of the type of treatment
189 citations
TL;DR: It is concluded that pronuclear fusion does not appear to be a prerequisite for the onset of DNA synthesis in Arbacia, and radioautographs of polyspermic zygotes demonstrated that unfused male pronuclei were able to synthesize DNA and substantiate the claim that pron nuclear fusion is not required for the initiation ofDNA synthesis.
53 citations
41 citations
TL;DR: Blocking experiments strongly suggest that the Glc-Gal-Hyl is one of the structural determinants involved in collagen-induced platelet aggregation.
Abstract: It is widely held that the tertiary structure of collagen is essential for induction of platelet aggregation. However, we have found that the purified α1 chain prepared from denatured chick skin collagen aggregates platelets. This activity appears to be confined to a distinct region of the molecule representing less than 4 percent of the length of the α1 chain. Of all of the cyanogen bromide peptides of the α1 chain tested, only one (α1-CB5) was active. This glycopeptide, devoid of any ordered tertiary structure, contains only 36 amino acids and one residue of O-α-D-glucopyranosyl-(1 → 2)-O-β-D-galactopyranosyloxy-(1 → 5)-lysine (Glc-Gal-Hyl). Blocking experiments strongly suggest that the Glc-Gal-Hyl is one of the structural determinants involved in collagen-induced platelet aggregation.
40 citations
33 citations
TL;DR: The morphology and origin of these tubules are compared and discussed with respect to similar extracellular tubules found associated with other cell types and it is concluded that such tubules, wherever they are found, may have a common function as yet unknown.
29 citations
TL;DR: The sodium 22 method of measuring cerebral infarction edema was less time consuming and easier than the wet weight-dry weight method, and served as a reliable means of quantitatively comparing the edema content in the hemispheres of animals with stroke.
Abstract: Sodium 22 was used to determine quantitatively cerebral infarction edema in cats after occlusion of the middle cerebral artery. A comparison was made of the sodium 22 edema determination with the wet weight-dry weight method of edema determination. There was a high degree of correlation between the two methods. The sodium 22 method of measuring cerebral infarction edema was less time consuming and easier than the wet weight-dry weight method, and served as a reliable means of quantitatively comparing the edema content in the hemispheres of animals with stroke.
21 citations
01 Jan 1973
TL;DR: A set of important principles of information processing in the nervous system that are derived from, or at least strongly suggested by, the mass of details available in the neurophysiological literature are discussed.
Abstract: Publisher Summary This chapter discusses integration in the central nervous system. The nervous system deals with time-varying signals, picked up by a wide variety of receptors. Each of these receptors modifies the signal that it receives from the external or internal environment of the animal. Consequently, the central nervous system, provided only with information reaching the receptors, must operate on this information in a form modified by the receptors. In many of these receptors, signals from the central nervous system adjust the rules by which the receptor modifies the signal from the environmental signal. Thus, the function of the central nervous system cannot be isolated from the function of the receptors. For survival value, the information in the nervous system becomes important only when it causes a change in the relationship between the animal and some part of its environment. This chapter discusses a set of important principles of information processing in the nervous system that are derived from, or at least strongly suggested by, the mass of details available in the neurophysiological literature. The chapter discusses the handling of single signals and also describes the capability of a network of simple elements .
15 citations
TL;DR: During the late 1960’s, aneurysm surgery became more refined and these improvements along with the technical, metabolic and hemorrhagic problems encountered with profound hypothermia and cardiac arrest led to the general disuse of this procedure in neurosurgery.
14 citations
14 citations
TL;DR: Analysis of the results demonstrated that alternating block was also intimately related to the alternation of preceding cycle lengths and probably resulted from alternate antegrade block of the instrumental branch accompanied by retrograde conduction through the accessory pathway offered by the other branch and the common myocardial bridge.
Abstract: Microelectrode studies were performed to produce alternation of coupled beats in the specialized conduction system of the heart and to determine the underlying mechanisms of their production. A typical preparation consisted of a superfused Y-shaped bifurcating segment of canine Purkinje tissue, in which the two branches of the Y were approximately symmetrical and terminated in a functionally communicating bridge of myocardium. Transmembrane potentials were recorded simultaneously from a proximal and a distal location in one branch of the Y. Stimulating the stem of the preparation with 60 pulse pairs/min at a critical coupling interval produced alternation of the coupled beats. Alternate reversal of the proximl-to-distal sequence of activation was observed under these circumstances. This finding probably resulted from alternate antegrade block of the instrumental branch accompanied by retrograde conduction through the accessory pathway offered by the other branch and the common myocardial bridge. The validity of this inference was confirmed by microelectrode exploration and by transection of the retrograde pathway. Analysis of the results demonstrated further that alternating block was also intimately related to the alternation of preceding cycle lengths.
TL;DR: In this article, the biologic value of textured vegetable protein equal to that of traditional sources of protein for human nutrition was investigated, and the results showed that textured vegetables have a higher protein content than traditional sources.
Abstract: Is the biologic value of textured vegetable protein equal to that of customary sources of protein for human nutrition?
[...]