Institution
University of Tennessee Health Science Center
Education•Memphis, Tennessee, United States•
About: University of Tennessee Health Science Center is a education organization based out in Memphis, Tennessee, United States. It is known for research contribution in the topics: Population & Transplantation. The organization has 15716 authors who have published 26884 publications receiving 1176697 citations.
Topics: Population, Transplantation, Kidney disease, Cancer, Receptor
Papers published on a yearly basis
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Fred Hutchinson Cancer Research Center1, National Institutes of Health2, University of Wisconsin-Madison3, University of Cambridge4, Northwestern University5, University of Washington6, Kaiser Permanente7, University of Arizona8, University of Tennessee Health Science Center9, University of Pittsburgh10, University of North Carolina at Chapel Hill11, Portland State University12, University of Massachusetts Medical School13, Stanford University14, Pfizer15
TL;DR: Recovery biomarker data were used in regression equations to calibrate self- Reports and the potential application of these equations to disease risk modeling is presented; the authors confirm the existence of systematic bias in dietary self-reports and provide methods of correcting for measurement error.
Abstract: Underreporting of energy consumption by self-report is well-recognized, but previous studies using recovery biomarkers have not been sufficiently large to establish whether participant characteristics predict misreporting. In 2004-2005, 544 participants in the Women's Health Initiative Dietary Modification Trial completed a doubly labeled water protocol (energy biomarker), 24-hour urine collection (protein biomarker), and self-reports of diet (assessed by food frequency questionnaire (FFQ)), exercise, and lifestyle habits; 111 women repeated all procedures after 6 months. Using linear regression, the authors estimated associations of participant characteristics with misreporting, defined as the extent to which the log ratio (self-reported FFQ/nutritional biomarker) was less than zero. Intervention women in the trial underreported energy intake by 32% (vs. 27% in the comparison arm) and protein intake by 15% (vs. 10%). Younger women had more underreporting of energy (p = 0.02) and protein (p = 0.001), while increasing body mass index predicted increased underreporting of energy and overreporting of percentage of energy derived from protein (p = 0.001 and p = 0.004, respectively). Blacks and Hispanics underreported more than did Caucasians. Correlations of initial measures with repeat measures (n = 111) were 0.72, 0.70, 0.46, and 0.64 for biomarker energy, FFQ energy, biomarker protein, and FFQ protein, respectively. Recovery biomarker data were used in regression equations to calibrate self-reports; the potential application of these equations to disease risk modeling is presented. The authors confirm the existence of systematic bias in dietary self-reports and provide methods of correcting for measurement error.
347 citations
TL;DR: It is reassuring that patients receiving treatment for ISH never perform worse than patients receiving placebo in terms of CVD events, and further studies need to determine whether excessively low DBP can be prevented by more careful titration of antihypertensive therapy while maintaining SBP control.
Abstract: Objective To assess the role of treated diastolic blood pressure (DBP) level in stroke, coronary heart disease (CHD), and cardiovascular disease (CVD) in patients with isolated systolic hypertension (ISH). Design An analysis of the 4736 participants in the Systolic Hypertension in the Elderly Program (SHEP) was undertaken. The SHEP was a randomized multicenter double-blind outpatient clinical trial of the impact of treating ISH in men and women aged 60 years and older. Main Outcome Measures Cox proportional hazards regression analysis, with DBP and systolic blood pressure (SBP) as time-dependent covariables. Results After adjustment for the baseline risk factors of race (black vs other), sex, use of antihypertensive medication before the study, a composite variable (diabetes, previous heart attack, or stroke), age, and smoking history (ever vs never) and adjustment for the SBP as a time-dependent variable, we found, for the active treatment group only, that a decrease of 5 mm Hg in DBP increased the risk for stroke (relative risk, [RR], 1.14; 95% confidence interval [CI], 1.05-1.22), for CHD (RR, 1.08; 95% CI, 1.00-1.16), and for CVD (RR, 1.11; 95% CI, 1.05-1.16). Conclusions Some patients with ISH may be treated to a level that uncovers subclinical disease, and some may be overtreated. Further studies need to determine whether excessively low DBP can be prevented by more careful titration of antihypertensive therapy while maintaining SBP control. It is reassuring that patients receiving treatment for ISH never perform worse than patients receiving placebo in terms of CVD events.
347 citations
TL;DR: In this paper, the authors focus on the functional analysis of conserved RNA secondary structures in the 5′ and 3′ of the betacoronavirus genomes and find evidence that an association between the 3′ and 5′UTRs is necessary for subgenomic RNA synthesis, but the basis for this association is not yet clear.
347 citations
TL;DR: In this paper, it was shown that a primary visual area and a primary somatosensory-somatomotor area are present in the avian Wulst; these areas are likely to be homologous to their counterparts in mammals.
347 citations
TL;DR: These data from a large multicenter collaborative study confirm and extend previous observations and show a consistent relationship between the timing of AMP and SSI risk with a trend toward lower risk occurring when AMP with cephalosporins and other antibiotics with short infusion times were given within 30 minutes prior to incision.
Abstract: Objective:The objective of this study is to determine the optimal timing for surgical antimicrobial prophylaxis (AMP).Summary Background Data:National AMP guidelines should be supported by evidence from large contemporary data sets.Methods:Twenty-nine hospitals prospectively obtained information on
346 citations
Authors
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| Name | H-index | Papers | Citations |
|---|---|---|---|
| George P. Chrousos | 169 | 1612 | 120752 |
| Steven N. Blair | 165 | 879 | 132929 |
| Bruce L. Miller | 163 | 1153 | 115975 |
| Ralph A. DeFronzo | 160 | 759 | 132993 |
| Frank J. Gonzalez | 160 | 1144 | 96971 |
| Robert G. Webster | 158 | 843 | 90776 |
| Anne B. Newman | 150 | 902 | 99255 |
| Ching-Hon Pui | 145 | 805 | 72146 |
| Barton F. Haynes | 144 | 911 | 79014 |
| Yoshihiro Kawaoka | 139 | 883 | 75087 |
| Seth M. Steinberg | 137 | 936 | 80148 |
| Richard J. Johnson | 137 | 880 | 72201 |
| Kristine Yaffe | 136 | 794 | 72250 |
| Leslie L. Robison | 131 | 854 | 64373 |
| Gerardo Heiss | 128 | 623 | 69393 |