scispace - formally typeset
Search or ask a question
Institution

University Of Tennessee System

EducationKnoxville, Tennessee, United States
About: University Of Tennessee System is a education organization based out in Knoxville, Tennessee, United States. It is known for research contribution in the topics: Population & Health care. The organization has 741 authors who have published 585 publications receiving 36866 citations. The organization is also known as: UT System.
Topics: Population, Health care, Lepton, Cancer, Muon


Papers
More filters
Journal ArticleDOI
TL;DR: Among patients with acute stroke who had last been known to be well 6 to 24 hours earlier and who had a mismatch between clinical deficit and infarct, outcomes for disability at 90 days were better with thrombectomy plus standard care than with standard care alone.
Abstract: BackgroundThe effect of endovascular thrombectomy that is performed more than 6 hours after the onset of ischemic stroke is uncertain. Patients with a clinical deficit that is disproportionately severe relative to the infarct volume may benefit from late thrombectomy. MethodsWe enrolled patients with occlusion of the intracranial internal carotid artery or proximal middle cerebral artery who had last been known to be well 6 to 24 hours earlier and who had a mismatch between the severity of the clinical deficit and the infarct volume, with mismatch criteria defined according to age (<80 years or ≥80 years). Patients were randomly assigned to thrombectomy plus standard care (the thrombectomy group) or to standard care alone (the control group). The coprimary end points were the mean score for disability on the utility-weighted modified Rankin scale (which ranges from 0 [death] to 10 [no symptoms or disability]) and the rate of functional independence (a score of 0, 1, or 2 on the modified Rankin scale, whic...

3,331 citations

Journal ArticleDOI
TL;DR: This manuscript focuses on the NCCN Guidelines Panel recommendations for the workup, primary treatment, risk reduction strategies, and surveillance specific to DCIS.
Abstract: Ductal carcinoma in situ (DCIS) of the breast represents a heterogeneous group of neoplastic lesions in the breast ducts. The goal for management of DCIS is to prevent the development of invasive breast cancer. This manuscript focuses on the NCCN Guidelines Panel recommendations for the workup, primary treatment, risk reduction strategies, and surveillance specific to DCIS.

1,545 citations

Journal ArticleDOI
TL;DR: This selection from the NCCN Guidelines for Non-Small Cell Lung Cancer (NSCLC) focuses on targeted therapies and immunotherapies for metastatic NSCLC, because therapeutic recommendations are rapidly changing for metastasis disease.
Abstract: This selection from the NCCN Guidelines for Non-Small Cell Lung Cancer (NSCLC) focuses on targeted therapies and immunotherapies for metastatic NSCLC, because therapeutic recommendations are rapidly changing for metastatic disease. For example, new recommendations were added for atezolizumab, ceritinib, osimertinib, and pembrolizumab for the 2017 updates.

1,003 citations

Journal ArticleDOI
TL;DR: This portion of the NCCN Guidelines discusses general principles for the diagnosis, staging, and treatment of STS of the extremities, superficial trunk, or head and neck; outlines treatment recommendations by disease stage; and reviews the evidence to support the guidelines recommendations.
Abstract: Soft tissue sarcomas (STS) are rare solid tumors of mesenchymal cell origin that display a heterogenous mix of clinical and pathologic characteristics. STS can develop from fat, muscle, nerves, blood vessels, and other connective tissues. The evaluation and treatment of patients with STS requires a multidisciplinary team with demonstrated expertise in the management of these tumors. The complete NCCN Guidelines for STS provide recommendations for the diagnosis, evaluation, and treatment of extremity/superficial trunk/head and neck STS, as well as intra-abdominal/retroperitoneal STS, gastrointestinal stromal tumors, desmoid tumors, and rhabdomyosarcoma. This portion of the NCCN Guidelines discusses general principles for the diagnosis, staging, and treatment of STS of the extremities, superficial trunk, or head and neck; outlines treatment recommendations by disease stage; and reviews the evidence to support the guidelines recommendations.

894 citations


Authors

Showing all 748 results

NameH-indexPapersCitations
Robert Stone1601756167901
Christopher P. Cannon1511118108906
Sevil Salur1471470106407
Yuri Gershtein1391558104279
Eva Halkiadakis137160497953
Amitabh Lath135164697861
Elliot Hughes134140497687
Alex J. Barker132127384746
Andrea Castro132150090019
Scott Thomas131121985507
John Paul Chou131119382912
Keith Rose12987675970
Dinko Ferencek128116179410
Christian Contreras-Campana12498770668
Daniel Duggan12477866716
Network Information
Related Institutions (5)
University of Pennsylvania
257.6K papers, 14.1M citations

79% related

University of North Carolina at Chapel Hill
185.3K papers, 9.9M citations

78% related

University of Wisconsin-Madison
237.5K papers, 11.8M citations

78% related

University of California, Davis
180K papers, 8M citations

78% related

University of Minnesota
257.9K papers, 11.9M citations

78% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20235
202217
20215
20203
20194
201811