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Institution

University of Texas Medical Branch

EducationGalveston, Texas, United States
About: University of Texas Medical Branch is a education organization based out in Galveston, Texas, United States. It is known for research contribution in the topics: Population & Virus. The organization has 22033 authors who have published 38268 publications receiving 1517502 citations. The organization is also known as: The University of Texas Medical Branch at Galveston & UTMB.


Papers
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Journal ArticleDOI
TL;DR: The mammalian urinary bladder epithelium (urothelium) performs the important function of storing urine for extended periods, while maintaining the urine composition similar to that delivered by the kidneys, which is illustrated by infectious cystitis.
Abstract: The mammalian urinary bladder epithelium (urothelium) performs the important function of storing urine for extended periods, while maintaining the urine composition similar to that delivered by the kidneys. The urothelium possesses four properties to perform this function. First, it offers a minimum epithelial surface area-to-urine volume; this reduces the surface area for passive movement of substances between lumen and blood. Second, the passive permeability of the apical membrane and tight junctions is very low to electrolytes and nonelectrolytes. Third, the urothelium has a hormonally regulated sodium absorptive system; thus passive movement of sodium from blood to urine is countered by active sodium reabsorption. Last, the permeability properties of the apical membrane and tight junctions of the urothelium are not altered by most substances found in the urine or blood. The importance of the barrier function of the urothelium is illustrated by infectious cystitis. The loss of the barrier function results in the movement of urinary constituents into the lamina propria and underlying muscle layers, resulting in suprapubic and lower back pain and frequent, urgent, and painful voiding.

323 citations

Journal ArticleDOI
TL;DR: A series of mutations in the recently emerged Indian Ocean Lineage that has adapted the virus for transmission for the first time by the Aedes albopictus urban mosquito vector are discussed, and CHIKV is compared to other arboviruses with and without similar histories of urbanization.

322 citations

Journal ArticleDOI
TL;DR: Specific combat experiences, including greater exposure to violent combat, killing another person, and contact with high levels of human trauma, were predictive of greater risk-taking propensity after homecoming, highlighting the importance of education and counseling for returning service members to mitigate the public health consequences of elevated risk-propensity associated with combat exposure.

322 citations

Journal ArticleDOI
TL;DR: The biology and significance of the epidermal growth factor (EGF) family is reviewed, with particular emphasis on understanding the integrated function of the family and the relationships between family members in the context of gastrointestinal physiology and pathophysiology.

321 citations

Journal ArticleDOI
TL;DR: The WLM behavioral intervention successfully achieved clinically significant short-term weight loss in a diverse population of high-risk patients, although the association between behavioral measures and weight loss differed by race and gender groups.

321 citations


Authors

Showing all 22143 results

NameH-indexPapersCitations
Stuart H. Orkin186715112182
Eric R. Kandel184603113560
John C. Morris1831441168413
Joseph Biederman1791012117440
Richard A. Gibbs172889249708
Timothy A. Springer167669122421
Gabriel N. Hortobagyi1661374104845
Roberto Romero1511516108321
Charles B. Nemeroff14997990426
Peter J. Schwartz147647107695
Clifford J. Woolf14150986164
Thomas J. Smith1401775113919
Edward C. Holmes13882485748
Jun Lu135152699767
Henry T. Lynch13392586270
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202330
2022196
20211,616
20201,487
20191,298
20181,152