Institution
University of the Philippines Diliman
Education•Quezon City, Philippines•
About: University of the Philippines Diliman is a education organization based out in Quezon City, Philippines. It is known for research contribution in the topics: Population & Politics. The organization has 4535 authors who have published 5027 publications receiving 66469 citations. The organization is also known as: UP Diliman & Peyups.
Topics: Population, Politics, Adsorption, Coral reef, Ophiolite
Papers published on a yearly basis
Papers
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TL;DR: The number of adults with raised blood pressure increased from 594 million in 1975 to 1·13 billion in 2015, with the increase largely in low-income and middle-income countries, and the contributions of changes in prevalence versus population growth and ageing to the increase.
1,573 citations
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Smithsonian Environmental Research Center1, University of California, San Diego2, Leibniz Institute of Marine Sciences3, University of Liège4, Monterey Bay Aquarium Research Institute5, Lund University6, Centre national de la recherche scientifique7, Fisheries and Oceans Canada8, Cayetano Heredia University9, University of the Philippines Diliman10, State University of New York College of Environmental Science and Forestry11, Kuwait Institute for Scientific Research12, University of Cape Town13, Department of Agriculture, Forestry and Fisheries14, Louisiana State University15, University of Maryland Center for Environmental Science16, University of South Florida St. Petersburg17, Polish Academy of Sciences18, University of Hong Kong19, East China Normal University20
TL;DR: Improved numerical models of oceanographic processes that control oxygen depletion and the large-scale influence of altered biogeochemical cycles are needed to better predict the magnitude and spatial patterns of deoxygenation in the open ocean, as well as feedbacks to climate.
Abstract: BACKGROUND Oxygen concentrations in both the open ocean and coastal waters have been declining since at least the middle of the 20th century. This oxygen loss, or deoxygenation, is one of the most important changes occurring in an ocean increasingly modified by human activities that have raised temperatures, CO 2 levels, and nutrient inputs and have altered the abundances and distributions of marine species. Oxygen is fundamental to biological and biogeochemical processes in the ocean. Its decline can cause major changes in ocean productivity, biodiversity, and biogeochemical cycles. Analyses of direct measurements at sites around the world indicate that oxygen-minimum zones in the open ocean have expanded by several million square kilometers and that hundreds of coastal sites now have oxygen concentrations low enough to limit the distribution and abundance of animal populations and alter the cycling of important nutrients. ADVANCES In the open ocean, global warming, which is primarily caused by increased greenhouse gas emissions, is considered the primary cause of ongoing deoxygenation. Numerical models project further oxygen declines during the 21st century, even with ambitious emission reductions. Rising global temperatures decrease oxygen solubility in water, increase the rate of oxygen consumption via respiration, and are predicted to reduce the introduction of oxygen from the atmosphere and surface waters into the ocean interior by increasing stratification and weakening ocean overturning circulation. In estuaries and other coastal systems strongly influenced by their watershed, oxygen declines have been caused by increased loadings of nutrients (nitrogen and phosphorus) and organic matter, primarily from agriculture; sewage; and the combustion of fossil fuels. In many regions, further increases in nitrogen discharges to coastal waters are projected as human populations and agricultural production rise. Climate change exacerbates oxygen decline in coastal systems through similar mechanisms as those in the open ocean, as well as by increasing nutrient delivery from watersheds that will experience increased precipitation. Expansion of low-oxygen zones can increase production of N 2 O, a potent greenhouse gas; reduce eukaryote biodiversity; alter the structure of food webs; and negatively affect food security and livelihoods. Both acidification and increasing temperature are mechanistically linked with the process of deoxygenation and combine with low-oxygen conditions to affect biogeochemical, physiological, and ecological processes. However, an important paradox to consider in predicting large-scale effects of future deoxygenation is that high levels of productivity in nutrient-enriched coastal systems and upwelling areas associated with oxygen-minimum zones also support some of the world’s most prolific fisheries. OUTLOOK Major advances have been made toward understanding patterns, drivers, and consequences of ocean deoxygenation, but there is a need to improve predictions at large spatial and temporal scales important to ecosystem services provided by the ocean. Improved numerical models of oceanographic processes that control oxygen depletion and the large-scale influence of altered biogeochemical cycles are needed to better predict the magnitude and spatial patterns of deoxygenation in the open ocean, as well as feedbacks to climate. Developing and verifying the next generation of these models will require increased in situ observations and improved mechanistic understanding on a variety of scales. Models useful for managing nutrient loads can simulate oxygen loss in coastal waters with some skill, but their ability to project future oxygen loss is often hampered by insufficient data and climate model projections on drivers at appropriate temporal and spatial scales. Predicting deoxygenation-induced changes in ecosystem services and human welfare requires scaling effects that are measured on individual organisms to populations, food webs, and fisheries stocks; considering combined effects of deoxygenation and other ocean stressors; and placing an increased research emphasis on developing nations. Reducing the impacts of other stressors may provide some protection to species negatively affected by low-oxygen conditions. Ultimately, though, limiting deoxygenation and its negative effects will necessitate a substantial global decrease in greenhouse gas emissions, as well as reductions in nutrient discharges to coastal waters.
1,469 citations
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TL;DR: This article showed that high and rising corruption increases income inequality and poverty by reducing economic growth, the progressivity of the tax system, the level and effectiveness of social spending, and the formation of human capital, and by perpetuating an unequal distribution of asset ownership and unequal access to education.
Abstract: This paper demonstrates that high and rising corruption increases income inequality and poverty by reducing economic growth, the progressivity of the tax system, the level and effectiveness of social spending, and the formation of human capital, and by perpetuating an unequal distribution of asset ownership and unequal access to education. These findings hold for countries with different growth experiences, at different stages of development, and using various indices of corruption. An important implication of these results is that policies that reduce corruption will also lower income inequality and poverty.
1,006 citations
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National University of Cordoba1, Leipzig University2, Helmholtz Centre for Environmental Research - UFZ3, Indiana University4, United Nations5, University of the West Indies6, Karlsruhe Institute of Technology7, National Autonomous University of Mexico8, University of Minnesota9, BirdLife International10, University of Cambridge11, University of British Columbia12, National University of Río Negro13, Chiba University14, National Institute for Environmental Studies15, Michigan State University16, United Nations University17, International Institute of Minnesota18, Stellenbosch University19, Commonwealth Scientific and Industrial Research Organisation20, Simón Bolívar University21, Hungarian Academy of Sciences22, University of Queensland23, Duke University24, Natural History Museum25, Imperial College London26, University of the West of England27, Stockholm University28, Clark University29, IFREMER30, University of Cape Town31, George Mason University32, Radboud University Nijmegen33, University of Oxford34, Royal Botanic Gardens35, University of the Philippines Diliman36
TL;DR: The first integrated global-scale intergovernmental assessment of the status, trends, and future of the links between people and nature provides an unprecedented picture of the extent of the authors' mutual dependence, the breadth and depth of the ongoing and impending crisis, and the interconnectedness among sectors and regions.
Abstract: The human impact on life on Earth has increased sharply since the 1970s, driven by the demands of a growing population with rising average per capita income. Nature is currently supplying more materials than ever before, but this has come at the high cost of unprecedented global declines in the extent and integrity of ecosystems, distinctness of local ecological communities, abundance and number of wild species, and the number of local domesticated varieties. Such changes reduce vital benefits that people receive from nature and threaten the quality of life of future generations. Both the benefits of an expanding economy and the costs of reducing nature's benefits are unequally distributed. The fabric of life on which we all depend-nature and its contributions to people-is unravelling rapidly. Despite the severity of the threats and lack of enough progress in tackling them to date, opportunities exist to change future trajectories through transformative action. Such action must begin immediately, however, and address the root economic, social, and technological causes of nature's deterioration.
913 citations
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TL;DR: It now seems that the Conus species will each use a distinctive assortment of peptides and that the pharmacological diversity in Conus venoms may be ultimately comparable to that of plant alkaloids or secondary metabolites of microorganisms.
Abstract: Conus venoms contain a remarkable diversity of pharmacologically active small peptides. Their targets are ion channels and receptors in the neuromuscular system. The venom of Conus geographus contains high-affinity peptides that act on voltage-sensitive calcium channels, sodium channels, N-methyl-D-aspartate (NMDA) receptors, acetylcholine receptors, and vasopressin receptors; many more peptides with still uncharacterized receptor targets are present in this venom. It now seems that the Conus species (approximately 500 in number) will each use a distinctive assortment of peptides and that the pharmacological diversity in Conus venoms may be ultimately comparable to that of plant alkaloids or secondary metabolites of microorganisms. The cone snails may generate this diverse spectrum of venom peptides by a "fold-lock-cut" synthetic pathway. These peptides are specific enough to discriminate effectively between closely related receptor subtypes and can be used for structure-function correlations.
562 citations
Authors
Showing all 4588 results
Name | H-index | Papers | Citations |
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Jean Rivier | 133 | 769 | 73919 |
Baldomero M. Olivera | 92 | 503 | 32064 |
Satoshi Kawata | 87 | 632 | 31450 |
Simon Henry Connell | 83 | 506 | 25147 |
J. Michael McIntosh | 67 | 280 | 15528 |
Rigoberto C. Advincula | 65 | 409 | 13632 |
David M. Virshup | 64 | 182 | 14429 |
Carl Abelardo T. Antonio | 60 | 106 | 66867 |
Madeleine J. H. van Oppen | 58 | 183 | 11169 |
Hervé Bellon | 50 | 185 | 9093 |
William R. Gray | 50 | 76 | 8440 |
David R. Hillyard | 46 | 130 | 8296 |
Jiangyong Hu | 45 | 184 | 6376 |
Matilde Leonardi | 45 | 358 | 8319 |
Chris M. Ireland | 45 | 158 | 5975 |