University of Tsukuba

About: University of Tsukuba is a education organization based out in Tsukuba, Ibaraki, Japan. It is known for research contribution in the topics: Population & Gene. The organization has 36352 authors who have published 79483 publications receiving 1934752 citations. The organization is also known as: Tsukuba daigaku & Tsukuba University.

HAL: Hybrid Assistive Limb Based on Cybernics

Abstract: We aim to develop the Hybrid Assistive Lims (HAL) in order to enhance and upgrade the human capabilities based on the frontier science Cybernics. Cybernics is a new domain of interdisciplinary research centered on cybernetics, mechatronics, and informatics, and integrates neuroscience, robotics, systems engineering, information technology, “kansei” engineering, ergonomics, physiology, social science, law, ethics, management, economics etc. Robot Suit HAL is a cyborg type robot that can expand, augment and support physical capability. The robot suit HAL has two types of control systems such as “Cybernic Voluntary Control System” and “Cybernic Autonomous Control System”. The application fields of HAL are medical welfare, heavy work support and entertainment etc. In this paper, the outline of HAL and some of the important algorithms and recent challenges are described.

Global variation in the effects of ambient temperature on mortality: a systematic evaluation.

Abstract: BACKGROUND: Studies have examined the effects of temperature on mortality in a single city, country, or region. However, less evidence is available on the variation in the associations between temperature and mortality in multiple countries, analyzed simultaneously. METHODS: We obtained daily data on temperature and mortality in 306 communities from 12 countries/regions (Australia, Brazil, Thailand, China, Taiwan, Korea, Japan, Italy, Spain, United Kingdom, United States, and Canada). Two-stage analyses were used to assess the nonlinear and delayed relation between temperature and mortality. In the first stage, a Poisson regression allowing overdispersion with distributed lag nonlinear model was used to estimate the community-specific temperature-mortality relation. In the second stage, a multivariate meta-analysis was used to pool the nonlinear and delayed effects of ambient temperature at the national level, in each country. RESULTS: The temperatures associated with the lowest mortality were around the 75th percentile of temperature in all the countries/regions, ranging from 66th (Taiwan) to 80th (UK) percentiles. The estimated effects of cold and hot temperatures on mortality varied by community and country. Meta-analysis results show that both cold and hot temperatures increased the risk of mortality in all the countries/regions. Cold effects were delayed and lasted for many days, whereas heat effects appeared quickly and did not last long. CONCLUSIONS: People have some ability to adapt to their local climate type, but both cold and hot temperatures are still associated with increased risk of mortality. Public health strategies to alleviate the impact of ambient temperatures are important, in particular in the context of climate change.

Measurement of photosynthetic production of a marine phytoplankton population using a stable 13C isotope

Abstract: The use of stable isotope of carbon, 13C, for the determination of the photosynthetic rate of a marine phytoplankton population was examined. Particular concern was paid to the effects of non-phytoplanktonic organic carbon and the enrichment of inorganic carbon on the estimation of the photosynthetic rate. Photosynthetic rates determined by the 13C method showed a remarkable agreement with those determined by the 14C method. Insitu determinations of photosynthetic rate were made in three different water types: open ocean, coastal and neritic waters, which included oligo- and mesotrophic waters, by using the 13C method established.

Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC Study

Abstract: Background Chronic rhinosinusitis (CRS) can be classified into CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). CRSwNP displays more intense eosinophilic infiltration and the presence of Th2 cytokines. Mucosal eosinophilia is associated with more severe symptoms and often requires multiple surgeries because of recurrence; however, even in eosinophilic CRS (ECRS), clinical course is variable. In this study, we wanted to set objective clinical criteria for the diagnosis of refractory CRS. Methods This was a retrospective study conducted by 15 institutions participating in the Japanese Epidemiological Survey of Refractory Eosinophilic Chronic Rhinosinusitis (JESREC). We evaluated patients with CRS treated with endoscopic sinus surgery (ESS), and risk of recurrence was estimated using Cox proportional hazard models. Multiple logistic regression models and receiver operating characteristics curves were constructed to create the diagnostic criterion for ECRS. Results We analyzed 1716 patients treated with ESS. To diagnose ECRS, the JESREC scoring system assessed unilateral or bilateral disease, the presence of nasal polyps, blood eosinophilia, and dominant shadow of ethmoid sinuses in computed tomography (CT) scans. The cutoff value of the score was 11 points (sensitivity: 83%, specificity: 66%). Blood eosinophilia (>5%), ethmoid sinus disease detected by CT scan, bronchial asthma, aspirin, and nonsteroidal anti-inflammatory drugs intolerance were associated significantly with recurrence. Conclusion We subdivided CRSwNP in non-ECRS, mild, moderate, and severe ECRS according to our algorithm. This classification was significantly correlated with prognosis. It is notable that this algorithm may give useful information to clinicians in the refractoriness of CRS before ESS or biopsy.

Artificial reality with force-feedback: development of desktop virtual space with compact master manipulator

Abstract: A new configuration of Human Interface for "artificial reality" is discussed. This paper describes a method of implementing force-feedback in a virtual space manipulation system. The system is composed of two subsystems, a real-time graphic display system and a tactile input device with reaction force generator. A specialized graphics computer (Stardent TITAN) provides a realtime image of the virtual space. A 9 degree-of-freedom manipulator has been developed as a tactile input device. The manipulator applies reaction forces to the fingers and palm of the operator. The generated forces are calculated from a solid model of the virtual space. The performance of the system is exemplified in manipulation of virtual solid objects such as a mockup for industrial design and a 3D animated character.