Showing papers by "University of Turin published in 1970"
TL;DR: Evidence of an active linkage between the human genes that control lactate dehydrogenase B and peptidase B is presented, but it is concluded that there is no link between the genes for lactate dehydration A and lactatehydrogenase A.
Abstract: Evidence of an active linkage between the human genes that control lactate dehydrogenase B and peptidase B is presented. It is also concluded that there is no link between the genes for lactate dehydrogenase A and lactate dehydrogenase B.
1,145 citations
TL;DR: An indirect immunofluorescence technique was applied to formalin-fixed, paraffin-embedded material from antral tissues of porcine stomach, and the argyrophil G cells, situated predominantly in the middle zone of the gastric glands, all showed positive gastrin immun ofluorescence.
Abstract: An indirect immunofluorescence technique, using anti-human gastrin serum, was applied to formalin-fixed, paraffin-embedded material from antral tissues of porcine stomach. After photographing the result, post-fixation in formalin was followed by the Grimelius silver technique. The argyrophil G cells, situated predominantly in the middle zone of the gastric glands, all showed positive gastrin immunofluorescence. Some weakly fluorescent cells failed to stain by the silver technique, suggesting that the latter is less sensitive than immunofluorescence in that it depends on the presence of the granular storage product.
78 citations
TL;DR: Activity and protein content were determined throughout the embryonic life of the chick in spinal and sympathetic ganglia and the greatest part of total cholinesterase activity was due to AChE.
Abstract: — Total cholinesterase, acetylcholinesterase, (AChE) and monoamine oxidase (MAO) activity and protein content were determined throughout the embryonic life of the chick in spinal and sympathetic ganglia. The greatest part of total cholinesterase activity was due to AChE.
AChE and MAO activity increased in both spinal and sympathetic ganglia very similarly from the 6th to the 12th day of incubation; from this day on a significant divergence occurred, mainly owing to a steady fall in spinal ganglion AChE, which decreased to approximately one tenth of the maximum value. The ratio of MAO activity in sympathetic and spinal ganglia increased from the 8th day onwards and approached 5·0 at hatching. The ratio between sympathetic and spinal ganglia, for AChE, choline acetylase (ChAc) and MAO activity, suggests a relationship between the maturation of the synapse in the sympathetic ganglia and the maximal activity of these enzymes.
48 citations
TL;DR: The incidence and histological characteristics of tumours induced in offspring by the administration of ethylnitrosourea to pregnant rats and the relation of the tumour type to the time of its appearance are discussed.
48 citations
TL;DR: It is suggested that pro-oxidant substances appearing as a consequence of CC14 poisoning may act at the level of initiation of translation, and cycloheximide prevents the changes provoked by CCI 4 in vivo.
46 citations
TL;DR: It is concluded that the seasonal ambisexual character here investigated, the height of the tail, is prolactin dependent, and the parallelism between water drive and tail height variations is stressed.
43 citations
TL;DR: It is suggested that the fall in blood phosphate values induced by adrenaline and, in part, that caused by insulin, is mediated by β-adrenergic receptors.
Abstract: 1 The effect of propranolol on adrenaline- and insulin-induced hypophosphataemia was studied in man 2 β-Adrenergic blockade with propranolol almost completely abolished and significantly inhibited adrenaline- and insulin-induced hypophosphataemia respectively; in addition, the drug clearly prevented the normally observed rise in plasma lactate, while causing only a slight change in blood glucose levels 3 It is suggested that the fall in blood phosphate values induced by adrenaline and, in part, that caused by insulin, is mediated by β-adrenergic receptors
30 citations
TL;DR: In this paper, the effect of substitutional solute elements of the 4th period on recrystallization of high-purity iron (99.998 %) has been carried out.
29 citations
TL;DR: Propranolol abolished the epinephrine-induced decrease in plasma potassium, in man and inhibited the rise in plasma lactic acid but only slightly affected the increase in blood glucose levels.
27 citations
TL;DR: The authors studied the induction of tumours of the central nervous system in rats by the chronic administration of methylnitrosourea, finding oligodendrogliomas, isomorphous and polymorphous gliomas were the most frequent tumours.
25 citations
TL;DR: In the liver of prolactin-treated Bufo bufo larvae, thyroid-dependent arginase activity is seen to arise at earlier stages than in controls, lending further support to the assumption that Prolactin induces activation rather than thyroid inhibition.
TL;DR: Maize rough dwarf virus was studied by electron microscopy in its principal insect vector, the planthopper Laodelphax striatellus (Fallen), and is therefore a virus that invades the animal host systematically.
TL;DR: A high frequency of Au is found either in populations in which the sanitary conditions are poor or in subjects inWhich the probability of infection is higher than average (subjects living in crowded communities; polytransfused patients ; laboratory staff etc.).
Abstract: The frequency of the Australia antigen in healthy individuals has been determined in different populations. It was found to be around 0.1-0.5~0 among Caucasians in USA and in other European countries [l, 31. Some tropical populations show a much higher frequency of Au positive subjects (up to 20.2% as in Cashinahua, Peru) [3]. Recent data concerning the Italian population show that the frequency of Au positive subjects [Au(l)] is around 0.5-1% [4, 6, 71. By contrast, as discussed below, the frequency of Au(1) among individuals of Sardinian ancestry is much higher [4]. I n these subjects the Au antigen persists for many years without clinical evidence of acute hepatitis. They are usually referred t o as ‘carriers’ of the Australia antigen. They represent a heterogeneous group in which a complex interaction between host and infectious agent is taking place. As in every infectious condition the environmental factors have great importance. Actually a high frequency of Au( 1) is found either in populations in which the sanitary conditions are poor or in subjects in which the probability of infection is higher than average (subjects living in crowded communities; polytransfused patients ; laboratory staff etc.). I n addition to environmental factors also genetic factors may be involved in determining the ‘carrier’ condition. The evidences which emphasize the influence of host factors are mainly the following: (1) The Australia antigen is very common in Down’s syndrome patients, but relatively rare in other mentally retarded children who live in the same institutions [9].
TL;DR: Two interpretations of the finding can be given: Either more than one precursor may participate in the formation of a focus or a differentiation switch may occur during the clonal expansion.
Abstract: 106 splenocytes from primed donors were injected, together with sheep erythrocytes (SRBC), into X-irradiated syngeneic mice. 8 days later the spleens were excised and cut into small fragments, keeping track of their location in the organ. Each fragment was cultured individually for 24 hr in the presence of 14C amino acids and the culture fluids were assayed for antibody activity. The antibody-producing fragments were found to be clustered in few restricted areas (foci) surrounded by negative tissue. The anti-SRBC antibody from single foci was purified by absorption on stroma followed by acid elution. Thereafter, it was subjected to electrophoresis and immunoelectrophoresis. The radioautography of the runs showed a considerable degree of homogeneity. Distinct and sharp spikes were localized in the beta and gamma region. The pattern of each focus is unique from the point of view of the number of spikes and their mobility. Eluates obtained from many pooled fragments gave a broad radioactive smear in beta-gamma region. Many foci synthesized antibody migrating as a single band. This homogeneous protein is probably the product of a clone of cells homogeneously differentiated. However, some foci producing two and probably more antibody bands were also encountered. Two interpretations of the finding can be given. Either more than one precursor may participate in the formation of a focus or a differentiation switch may occur during the clonal expansion.
TL;DR: DPPD, given by the intraperitoneal route, prevents rat liver from the fat infiltration induced by 1.5% orotic acid in the diet and in vitro production of MDA by liver homogenate appears to be stimulated during the earliest stages of orotics acid feeding.
TL;DR: The monodromy rings of Feynman integrals for one loop graphs with an arbitrary number of lines were determined in this paper, where they were shown to be monomorphic.
Abstract: The monodromy rings of Feynman integrals for one loop graphs with an arbitrary number of lines are determined.
TL;DR: A histochemical analysis of tumors induced in the rat both through nitrosoethylurea transplacental administration, and methylnitrosourea i.v. chronic administration has been performed.
Abstract: A histochemical analysis of tumors induced in the rat both through nitrosoethylurea transplacental administration, and methylnitrosourea i.v. chronic administration has been performed. The hydrolytic enzyme activities, acid phosphatase, non specific esterase, beta-glucuronidase, alkaline phosphatase have been studied in neurinomas and gliomas. The findings are compared with those in human tumors.
TL;DR: This paper presented a contrastive analysis of two discourse markers, i.e., the Italian "allora" and the Spanish "entonces", in an audiovisual corpus of L2 Italian.
Abstract: The aim of this paper is to present a first approach to the contrastive analysis of two discourse markers – the Italian "allora" and the Spanish "entonces". The two discourse markers have similar pragmatic functions and similar semantic values acquired in discourse, especially in conversational inter- action. However some differences in these interactional uses explain why Spanish learners of L2 Italian have difficulties in the use of the Italian "allora". Our point of departure is a descriptive analysis of both elements in interactional linguistic contexts. Next we examine "allora"’s functions in an audiovisual corpus of L2 Italian.
TL;DR: In this article, the effects of extrinsic and intraninsic denervation and of combined experimental hyperpertrophy on rabbit Ileum wall were investigated. But they did not consider the effect of choline acetyltransferase activity.
Abstract: (1970). Choline Acetyltransferase Activity of Rabbit Ileum Wall. the Effects of Extrinsic and Intrinsic Denervation and of Combined Experimental Hypertrophy. Archives Internationales de Physiologie et de Biochimie: Vol. 78, No. 1, pp. 141-152.
TL;DR: In this paper, the 9-phenyl thiaxanthyl radical has been obtained from the corresponding cation and a complete analysis of its E.S.R. spectrum has been achieved by using some deuterated derivatives as well as computer simulated spectra.
Abstract: The 9-phenyl thiaxanthyl radical has been obtained from the corresponding cation. A complete analysis of its E.S.R. spectrum has been achieved by using some deuterated derivatives as well as computer simulated spectra. The unusual ratio of the ortho/para hyperfine splittings (✠) has been interpreted as due to the occurrence of restricted rotation of the phenyl ring. Molecular orbital calculations indicate that the experimental results may be interpreted by assuming the phenyl ring to be twisted from the heterocyclic plane by an angle of about 72°. No significant differences were observed between the values of the spin density distribution calculated with standard p and d models.
TL;DR: In this article, the spectra of fast photoprotons from the reaction 7 Li(γ, p) 6 He have been measured at 14 bremsstrahlung end-point energies from 50 to 84 MeV.
01 Jan 1970
TL;DR: The research reported here was undertaken to study the different types of cattle red cell carbonic anhydrase, including gene-controlled multiple forms of enzymes.
Abstract: Studies of gene-controlled multiple forms of enzymes are particularly important with regard to the problems of the physiological activity of the enzymes present With this in mind, the research reported here was undertaken to study the different types of cattle red cell carbonic anhydrase
TL;DR: In this paper, the rate of formation of the monosalicylato complex of iron(III) has been investigated in acidic aqueous solution at 20.0, 25.0 and 30.0°C and ionic strength 1.010.
TL;DR: In this article, negative pion radiative capture differential cross-sections at forward c.m. gamma angles (around 30°) have been measured at nine different incident energies between 110 MeV and 270 MeV.
TL;DR: The data suggest that beta adrenergic receptors mediate a tonic vasodilator influence on the mesenteric and skeletal muscle circulations, in which these receptors abound, which seem more consistent with a different local metabolic response than with an uneven density of beta receptors.
Abstract: The effects of blockade and stimulation of beta adrenergic receptors on mesenteric, renal and hindlimb circulations have been investigated in unanesthetized resting dogs. Propranolol and isoproterenol have been used for beta blockade and stimulation, respectively. The changes in oxygen consumption in the hindlimb following beta receptor stimulation have also been studied in some experiments performed under anesthesia.
TL;DR: In this paper, yields and reduced specific viscosities of the products of the sodium tert-butoxide catalyzed hydrogen transfer polymerization at 100°C of acrylamide in 1-methyl-2-pyrrolidone have been determined as a function of time of polymerization.
Abstract: Yields and reduced specific viscosities of the products of the sodium tert-butoxide catalyzed hydrogen transfer polymerization at 100°C of acrylamide in 1-methyl-2-pyrrolidone have been determined as a function of time of polymerization. The results conclusively prove a stepwise chain growth mechanism since the early stages of the reaction.
Ausbeuten und reduzierte spezifische Viskositaten der bei 100°C in 1-Methyl-2-pyrrolidon als Losungsmittel verlaufenden, durch Natrium-tert-butylalkoholat katalysierten Polymerisation von Acrylamid, die unter Wasserstoffverschiebung vor sich geht, wurden in Abhangigkeit von der Polymerisationszeit bestimmt. Die Versuchsergebnisse lassen schon vom Beginn der Reaktion an eindeutig auf einen schrittweisen Kettenwachstumsmechanismus schliesen.
TL;DR: The haematological picture is similar to that observed in other haemolytic anaemias due to unstable haemoglobins and the disease is inherited as a Mendelian co‐dominant, non‐sex‐linked character.
Abstract: Summary Haematological and clinical features of the haemolytic anaemia due to haemoglobin Torino are reported. The haematological picture is similar to that observed in other haemolytic anaemias due to unstable haemoglobins. The disease, present in three members of the same family, is inherited as a Mendelian co-dominant, non-sex-linked character.
The disease is caused by the presence of haemoglobin Torino in erythrocytes and sulphonamide can provoke haemolytic crises. Besides the globin abnormality a decrease in porphobilinogen synthesis was demonstrated. Splenectomy improves the haematological state and clinical course.
TL;DR: A fall in the number of stem cells available for erythroblastic differentiation and ineffective erythropoiesis are held to be the principal mechanisms responsible for anaemia in AML.