Institution
University of Turku
Education•Turku, Finland•
About: University of Turku is a education organization based out in Turku, Finland. It is known for research contribution in the topics: Population & Galaxy. The organization has 16296 authors who have published 45124 publications receiving 1505428 citations. The organization is also known as: Turun yliopisto & Åbo universitet.
Topics: Population, Galaxy, Context (language use), Poison control, Cancer
Papers published on a yearly basis
Papers
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TL;DR: It is concluded that influenza vaccination decreases the incidence of acute otitis media in children during an influenza A epidemic, suggesting also that other vaccines against respiratory viruses may be an effective way to reduce the incidence.
Abstract: • We studied a new approach to the prevention of acute otitis media through the administration of influenza vaccine to 187 day-care center children aged 1 to 3 years before the influenza A epidemic of 1988-1989. The control group consisted of 187 unvaccinated children of similar age and background. During the 6-week study period, influenza A infection was diagnosed in five (3%) of 187 vaccines and in 29 (16%) of 187 controls. Acute otitis media developed in three (60%) of five vaccines with an influenza A infection compared with 18 (67%) of 27 controls (excluded were two children with a double viral infection). The incidence of acute otitis media associated with influenza A was reduced by 83% in the vaccines. The total number of children with acute otitis media in the vaccine group was 35, compared with 55 in the control group, disclosing a 36% reduction among the vaccinees. We conclude that influenza vaccination decreases the incidence of acute otitis media in children during an influenza A epidemic, suggesting also that other vaccines against respiratory viruses may be an effective way to reduce the incidence of acute otitis media. ( AJDC . 1991;145:445-448)
306 citations
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TL;DR: A number of human studies have clearly demonstrated that yoghurt containing viable bacteria improves lactose digestion and eliminates symptoms of lactose intolerance, and these cultures clearly fulfil the current concept of probiotics.
Abstract: Probiotics are live micro-organisms that when administered in adequate amounts confer a health benefit on the host. Consumption of yoghurt has been shown to induce measurable health benefits linked to the presence of live bacteria. A number of human studies have clearly demonstrated that yoghurt containing viable bacteria (Streptococcus thermophilus and Lactobacillus delbrueckii sp. bulgaricus) improves lactose digestion and eliminates symptoms of lactose intolerance. Thus, these cultures clearly fulfil the current concept of probiotics.
306 citations
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TL;DR: Results show that thermally hydrocarbonized porous silicon (THCPSi) nanoparticles did not induce any significant toxicity, oxidative stress, or inflammatory response in Caco-2 and RAW 264.7 macrophage cells.
Abstract: Porous silicon (PSi) particles have been studied for the effects they elicit in Caco-2 and RAW 264.7 macrophage cells in terms of toxicity, oxidative stress, and inflammatory response. The most suitable particles were then functionalized with a novel 18F label to assess their biodistribution after enteral and parenteral administration in a rat model. The results show that thermally hydrocarbonized porous silicon (THCPSi) nanoparticles did not induce any significant toxicity, oxidative stress, or inflammatory response in Caco-2 and RAW 264.7 macrophage cells. Fluorescently labeled nanoparticles were associated with the cells surface but were not extensively internalized. Biodistribution studies in rats using novel 18F-labeled THCPSi nanoparticles demonstrated that the particles passed intact through the gastrointestinal tract after oral administration and were also not absorbed from a subcutaneous deposit. After intravenous administration, the particles were found mainly in the liver and spleen, indicating...
305 citations
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TL;DR: In this paper, the authors analyzed patterns of participation and discourse mediated by Virtual Web School (VWS) and found that the density of interaction among participants was high, and all the participants used VWS to some extent.
305 citations
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TL;DR: The increase in diastolic diameter 1-4 wk after infarction correlated with cardiomyocyte apoptosis in the noninfarcted myocardium, which quantitatively contributed most (>50%) to the apoptotic cell loss by 4 wk.
Abstract: We investigated the role of cardiomyocyte apoptosis in the remodeling of the left ventricle from 24 h to 12 wk after myocardial infarction in the rat. Infarct size planimetry, quantification of cardiomyocyte apoptosis, terminal deoxynucleotide transferase-mediated dUTP nick-end labeling (TUNEL) methodology, and echocardiography (left ventricular diastolic diameter and ejection fraction) were performed. Sham-operated animals showed low rates of cardiomyocyte apoptosis (0.03%) and no change in diastolic diameter or ejection fraction during the study. Twenty-four hours after infarction, TUNEL positivity was high in the infarct areas (1.4%) and border zones (4.9%). It declined to 0.34% (P 50%) to the apoptotic cell loss by 4 wk.
305 citations
Authors
Showing all 16461 results
Name | H-index | Papers | Citations |
---|---|---|---|
Kari Alitalo | 174 | 817 | 114231 |
Mika Kivimäki | 166 | 1515 | 141468 |
Jaakko Kaprio | 163 | 1532 | 126320 |
Veikko Salomaa | 162 | 843 | 135046 |
Markus W. Büchler | 148 | 1545 | 93574 |
Eugene C. Butcher | 146 | 446 | 72849 |
Steven Williams | 144 | 1375 | 86712 |
Terho Lehtimäki | 142 | 1304 | 106981 |
Olli T. Raitakari | 142 | 1232 | 103487 |
Pim Cuijpers | 136 | 982 | 69370 |
Jeroen J. Bax | 132 | 1306 | 74992 |
Sten Orrenius | 130 | 447 | 57445 |
Aarno Palotie | 129 | 711 | 89975 |
Stefan W. Hell | 127 | 577 | 65937 |
Carlos López-Otín | 126 | 494 | 83933 |