Institution
University of Turku
Education•Turku, Finland•
About: University of Turku is a education organization based out in Turku, Finland. It is known for research contribution in the topics: Population & Galaxy. The organization has 16296 authors who have published 45124 publications receiving 1505428 citations. The organization is also known as: Turun yliopisto & Åbo universitet.
Topics: Population, Galaxy, Poison control, Health care, Pregnancy
Papers published on a yearly basis
Papers
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TL;DR: In this article, a review of public participation GIS and participatory GIS (PGIS) approaches for ecosystem services to identify current and best practice has been conducted to evaluate the methods to identify best practice.
Abstract: We review public participation GIS (PPGIS) and participatory GIS (PGIS) approaches for ecosystem services to identify current and best practice. PPGIS/PGIS are spatially explicit methods that have evolved over the past decade to identify a range of ecosystem services. Although PPGIS/PGIS methods demonstrate high potential for the identification of ecosystem services, especially cultural services, there has been no review to evaluate the methods to identify best practice. Through examination of peer-reviewed, empirical PPGIS/PGIS studies, we describe the types of ecosystem services mapped, the spatial mapping methods, the sampling approaches and range of participants, the types of spatial analyses performed, and the methodological trade-offs associated with each PPGIS/PGIS mapping approach. We found that multiple methods were implemented in nearly 30 case studies worldwide with the mapping of cultural and provisioning services being most common. There was little evidence that mapped ecosystem data was used for actual decision support in land use planning. Best practice has yet to coalesce in this field that has been dominated by methodological pluralism and case study research. We suggest greater use of experimental design and long-term case studies where the influence of mapped ecosystem services on land use decisions can be assessed.
381 citations
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TL;DR: The G-to-A change at nt 3460 is the second mutation so far detected in LHON, and abolishes an AhaII restriction site and thus can be detected easily by RFLP analysis.
Abstract: A single base mutation at nucleotide position 3460 (nt 3460) in the ND1 gene in human mtDNA was found to be associated with Leber hereditary optic neuroretinopathy (LHON). The G-to-A mutation converts an alanine to a threonine at the 52d codon of the gene. The mutation also abolishes an AhaII restriction site and thus can be detected easily by RFLP analysis. The mutation was found in three independent Finnish LHON families but in none of the 60 controls. None of the families with the nt 3460 mutation in ND1 had the previously reported nt 11778 mutation in the ND4 gene. The G-to-A change at nt 3460 is the second mutation so far detected in LHON.
380 citations
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TL;DR: Caesarean born infants have a more slowly diversifying microbiota, with differences reported from normally born infants, even after six months of age.
Abstract: Intestinal microbiota development begins immediately following birth.1 The composition of the infant’s evolving microbiota is initially defined by the mother, the source of the newborn’s first microbial inoculum. Colonising bacteria rapidly adapt to breast milk and epithelial mucins as sources of nutrients.
The prevalence of caesarean section delivery in Western countries is increasing. Caesarean born babies are deprived of contact with the maternal/vaginal microbiota and the first exposure is characterised by a lack of strict anaerobes and the presence of facultative anaerobes such as Clostridium species.2 Caesarean born infants have a more slowly diversifying microbiota, with differences reported from normally born infants, even after six months of age. Aberrancies in early microbiota acquisition can affect immunophysiological development with a heightened disease risk.2,3 This …
379 citations
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TL;DR: Net protection of SGLT2 inhibitors against cardiovascular outcomes and death is suggested, driven by findings for empagliflozin (the only S GLT2 inhibitor for which data from a dedicated long-term cardiovascular safety trial have been reported), although results for the other drugs in the class were not clearly different.
378 citations
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TL;DR: Abundant evidence implies that specific strains selected from the healthy gut microflora exhibit powerful antipathogenic and anti-inflammatory capabilities, and are consequently involved with enhanced colonisation resistance in the intestine.
Abstract: Probiotic therapy is based on the concept of normal healthy microflora. The development of novel means of characterising the gut microflora, in particular those based on the different levels of conservation in the ribosomal RNA sequences of different genera, have opened up new angles on the role of the gut microflora in health and disease. Components of the human intestinal microflora or organisms entering the intestine may have harmful or beneficial effects on human health. Abundant evidence implies that specific strains selected from the healthy gut microflora exhibit powerful antipathogenic and anti-inflammatory capabilities, and are consequently involved with enhanced colonisation resistance in the intestine. Realisation of this has led to the introduction of novel modes of therapeutic and prophylactic intervention based on the consumption of mono and mixed cultures of beneficial live microorganisms as probiotics.
376 citations
Authors
Showing all 16461 results
Name | H-index | Papers | Citations |
---|---|---|---|
Kari Alitalo | 174 | 817 | 114231 |
Mika Kivimäki | 166 | 1515 | 141468 |
Jaakko Kaprio | 163 | 1532 | 126320 |
Veikko Salomaa | 162 | 843 | 135046 |
Markus W. Büchler | 148 | 1545 | 93574 |
Eugene C. Butcher | 146 | 446 | 72849 |
Steven Williams | 144 | 1375 | 86712 |
Terho Lehtimäki | 142 | 1304 | 106981 |
Olli T. Raitakari | 142 | 1232 | 103487 |
Pim Cuijpers | 136 | 982 | 69370 |
Jeroen J. Bax | 132 | 1306 | 74992 |
Sten Orrenius | 130 | 447 | 57445 |
Aarno Palotie | 129 | 711 | 89975 |
Stefan W. Hell | 127 | 577 | 65937 |
Carlos López-Otín | 126 | 494 | 83933 |