University of Udine

About: University of Udine is a education organization based out in Udine, Italy. It is known for research contribution in the topics: Population & Large Hadron Collider. The organization has 6745 authors who have published 20530 publications receiving 669088 citations. The organization is also known as: Università degli Studi di Udine & Universita degli Studi di Udine.

Hyperglycemia-Induced Thrombin Formation in Diabetes: The Possible Role of Oxidative Stress

Abstract: Diabetes is characterized by the existence of a thrombosis-prone condition, possibly related to hyperglycemia However, the mechanism linking hyperglycemia to the activation of the coagulation cascade is still unclear It has been recently suggested that diabetes is accompanied by increased oxidative stress In this work, the possibility that oxidative stress may be involved in the hyperglycemia-induced coagulation activation has been evaluated Prothrombin fragment 1 + 2 (F1 + 2), which represents a reliable marker of the amount of thrombin released in the circulation, has been chosen for studying thrombin formation in vivo In nine type II diabetic patients and in seven healthy control subjects, matched for age and body mass index, three different experiments were performed: oral glucose tolerance test (OGTT), intravenous antioxidant glutathione (GSH) administration for 2 h, and OGTT plus intravenous GSH administration Samples were drawn at -15 min and every 30 min from 0 to 180 min During the OGTT, F1 + 2 significantly increased in both diabetic and healthy subjects GSH administration during OGTT normalized this phenomenon GSH administration alone significantly decreased F1 + 2 in diabetic patients, while no effect was observed in the normal subjects These data suggest that hyperglycemia may induce thrombin activation, possibly inducing an oxidative stress, and that antioxidant GSH may counterbalance this effect

Measurement of the inelastic proton-proton cross section at √s=13 TeV with the ATLAS detector at the LHC

Abstract: This Letter presents a measurement of the inelastic proton-proton cross section using 60 μb^{-1} of pp collisions at a center-of-mass energy sqrt[s] of 13 TeV with the ATLAS detector at the LHC. Inelastic interactions are selected using rings of plastic scintillators in the forward region (2.07 10^{-6}, where M_{X} is the larger invariant mass of the two hadronic systems separated by the largest rapidity gap in the event. In this ξ range the scintillators are highly efficient. For diffractive events this corresponds to cases where at least one proton dissociates to a system with M_{X}>13 GeV. The measured cross section is compared with a range of theoretical predictions. When extrapolated to the full phase space, a cross section of 78.1±2.9 mb is measured, consistent with the inelastic cross section increasing with center-of-mass energy.

Identification and characterization of microsatellites in Norway spruce (Picea abies K.).

Abstract: Norway spruce (Picea abies) genomic libraries were screened for presence of dinucleotide AC/GT and AG/CT microsatellites (or simple sequence repeats). On average, one (AG)n microsatellite every 194...