Institution
University of Utah
Education•Salt Lake City, Utah, United States•
About: University of Utah is a education organization based out in Salt Lake City, Utah, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 52894 authors who have published 124076 publications receiving 5265834 citations. The organization is also known as: The U & The University of Utah.
Topics: Population, Poison control, Health care, Cancer, Transplantation
Papers published on a yearly basis
Papers
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01 Jul 2008TL;DR: A wireless wearable system that was developed to provide quantitative gait analysis outside the confines of the traditional motion laboratory, the GaitShoe proved highly capable of detecting heel-strike and toe-off, as well as estimating foot orientation and position, inter alia.
Abstract: We describe a wireless wearable system that was developed to provide quantitative gait analysis outside the confines of the traditional motion laboratory. The sensor suite includes three orthogonal accelerometers, three orthogonal gyroscopes, four force sensors, two bidirectional bend sensors, two dynamic pressure sensors, as well as electric field height sensors. The "GaitShoe" was built to be worn in any shoe, without interfering with gait and was designed to collect data unobtrusively, in any environment, and over long periods. The calibrated sensor outputs were analyzed and validated with results obtained simultaneously from the Massachusetts General Hospital, Biomotion Laboratory. The GaitShoe proved highly capable of detecting heel-strike and toe-off, as well as estimating foot orientation and position, inter alia.
736 citations
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TL;DR: The molecular cloning of human PHS type II from an endothelial cell cDNA library is reported and it is concluded that expression of PHS II may have important pathophysiological effects in the vasculature.
736 citations
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TL;DR: In this paper, a least-squares migration algorithm is presented that reduces the migration artifacts arising from incomplete data by using a preconditioned linear conjugate gradient scheme that employs regularization.
Abstract: A least-squares migration algorithm is presented that reduces the migration artifacts (i.e., recording footprint noise) arising from incomplete data. Instead of migrating data with the adjoint of the forward modeling operator, the normal equations are inverted by using a preconditioned linear conjugate gradient scheme that employs regularization. The modeling operator is constructed from an asymptotic acoustic integral equation, and its adjoint is the Kirchhoff migration operator. We tested the performance of the least-squares migration on synthetic and field data in the cases of limited recording aperture, coarse sampling, and acquisition gaps in the data. Numerical results show that the least-squares migrated sections are typically more focused than are the corresponding Kirchhoff migrated sections and their reflectivity frequency distributions are closer to those of the true model frequency distribution. Regularization helps attenuate migration artifacts and provides a sharper, better frequency distribution of estimated reflectivity. The least-squares migrated sections can be used to predict the missing data traces and interpolate and extrapolate them according to the governing modeling equations. Several field data examples are presented. A ground-penetrating radar data example demonstrates the suppression of the recording footprint noise due to a limited aperture, a large gap, and an undersampled receiver line. In addition, better fault resolution was achieved after applying least-squares migration to a poststack marine data set. And a reverse vertical seismic profiling example shows that the recording footprint noise due to a coarse receiver interval can be suppressed by least-squares migration.
736 citations
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TL;DR: Fiber consumption predicted insulin levels, weight gain, and other CVD risk factors more strongly than did total or saturated fat consumption, and high-fiber diets may protect against obesity and CVD by lowering insulin levels.
Abstract: ContextDietary composition may affect insulin secretion, and high insulin levels,
in turn, may increase the risk for cardiovascular disease (CVD).ObjectiveTo examine the role of fiber consumption and its association with insulin
levels, weight gain, and other CVD risk factors compared with other major
dietary components.Design and SettingThe Coronary Artery Risk Development in Young Adults (CARDIA) Study,
a multicenter population-based cohort study of the change in CVD risk factors
over 10 years (1985-1986 to 1995-1996) in Birmingham, Ala; Chicago, Ill; Minneapolis,
Minn; and Oakland, Calif.ParticipantsA total of 2909 healthy black and white adults, 18 to 30 years of age
at enrollment.Main Outcome MeasuresBody weight, insulin levels, and other CVD risk factors at year 10,
adjusted for baseline values.ResultsAfter adjustment for potential confounding factors, dietary fiber showed
linear associations from lowest to highest quintiles of intake with the following:
body weight (whites: 174.8-166.7 lb [78.3-75.0 kg], P<.001;
blacks: 185.6-177.6 lb [83.5-79.9 kg], P = .001),
waist-to-hip ratio (whites: 0.813-0.801, P = .004;
blacks: 0.809-0.799, P = .05), fasting insulin adjusted
for body mass index (whites: 77.8-72.2 pmol/L [11.2-10.4 µU/mL], P = .007;blacks: 92.4-82.6 pmol/L [13.3-11.9 µU/mL], P = .01) and 2-hour postglucose insulin adjusted for body
mass index (whites: 261.1-234.7 pmol/L [37.6-33.8 µU/mL], P = .03; blacks: 370.2-259.7 pmol/L [53.3-37.4 µU/mL], P<.001). Fiber was also associated with blood pressure
and levels of triglyceride, high-density lipoprotein cholesterol, low-density
lipoprotein cholesterol, and fibrinogen; these associations were substantially
attenuated by adjustment for fasting insulin level. In comparison with fiber,
intake of fat, carbohydrate, and protein had inconsistent or weak associations
with all CVD risk factors.ConclusionsFiber consumption predicted insulin levels, weight gain, and other CVD
risk factors more strongly than did total or saturated fat consumption. High-fiber
diets may protect against obesity and CVD by lowering insulin levels.
735 citations
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TL;DR: Exercise training resulted in improved fitness and had a positive impact on factors related to quality of life and no changes were observed for EX or NEX groups on the FSS.
Abstract: Fifty-four multiple sclerosis (MS) patients were randomly assigned to exercise (EX) or nonexercise (NEX) groups. Before and after 15 weeks of aerobic training, aspects of fitness including maximal aerobic capacity (VO2max), isometric strength, body composition, and blood lipids were measured. Daily activities, mood, fatigue, and disease status were measured by the Profile of Mood States (POMS), Sickness Impact Profile (SIP), Fatigue Severity Scale (FSS), and neurological examination. Training consisted of 3 x 40-minute sessions per week of combined arm and leg ergometry. Expanded Disability Status Scale (EDSS) scores were unchanged, except for improved bowel and bladder function in the EX group. Compared with baseline, the EX group demonstrated significant increases in VO2max, upper and lower extremity strength, and significant decreases in skinfolds, triglyceride, and very-low-density lipoprotein (VLDL). For the EX group, POMS depression and anger scores were significantly reduced at weeks 5 and 10, and fatigue was reduced at week 10. The EX group improved significantly on all components of the physical dimension of the SIP and showed significant improvements for social interaction, emotional behavior, home management, total SIP score, and recreation and past times. No changes were observed for EX or NEX groups on the FSS. Exercise training resulted in improved fitness and had a positive impact on factors related to quality of life.
734 citations
Authors
Showing all 53431 results
Name | H-index | Papers | Citations |
---|---|---|---|
Bert Vogelstein | 247 | 757 | 332094 |
George M. Whitesides | 240 | 1739 | 269833 |
Hongjie Dai | 197 | 570 | 182579 |
Robert M. Califf | 196 | 1561 | 167961 |
Frank E. Speizer | 193 | 636 | 135891 |
Yusuke Nakamura | 179 | 2076 | 160313 |
David L. Kaplan | 177 | 1944 | 146082 |
Marc G. Caron | 173 | 674 | 99802 |
George M. Church | 172 | 900 | 120514 |
Steven P. Gygi | 172 | 704 | 129173 |
Lily Yeh Jan | 162 | 467 | 73655 |
Tobin J. Marks | 159 | 1621 | 111604 |
David W. Bates | 159 | 1239 | 116698 |
Alfred L. Goldberg | 156 | 474 | 88296 |
Charles M. Perou | 156 | 573 | 202951 |