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Institution

University of Utah

EducationSalt Lake City, Utah, United States
About: University of Utah is a education organization based out in Salt Lake City, Utah, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 52894 authors who have published 124076 publications receiving 5265834 citations. The organization is also known as: The U & The University of Utah.


Papers
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Journal ArticleDOI
TL;DR: This new form of hybrid h-BNC material enables the development of bandgap-engineered applications in electronics and optics and properties that are distinct from those of graphene and h-BN.
Abstract: (1) Department of Mechanical Engineering and Materials Science, Rice University, Houston, TX 77005, United States

1,995 citations

Journal ArticleDOI
TL;DR: The parmbsc0 force field as mentioned in this paper is a refinement of the AMBER parm99 force field, where emphasis has been made on the correct representation of the a/g concerted rotation in nucleic acids (NAs).

1,982 citations

Journal ArticleDOI
TL;DR: Exome sequencing of a small number of unrelated affected individuals is a powerful, efficient strategy for identifying the genes underlying rare mendelian disorders and will likely transform the genetic analysis of monogenic traits.
Abstract: We demonstrate the first successful application of exome sequencing to discover the gene for a rare mendelian disorder of unknown cause, Miller syndrome (MIM%263750). For four affected individuals in three independent kindreds, we captured and sequenced coding regions to a mean coverage of 40x and sufficient depth to call variants at approximately 97% of each targeted exome. Filtering against public SNP databases and eight HapMap exomes for genes with two previously unknown variants in each of the four individuals identified a single candidate gene, DHODH, which encodes a key enzyme in the pyrimidine de novo biosynthesis pathway. Sanger sequencing confirmed the presence of DHODH mutations in three additional families with Miller syndrome. Exome sequencing of a small number of unrelated affected individuals is a powerful, efficient strategy for identifying the genes underlying rare mendelian disorders and will likely transform the genetic analysis of monogenic traits.

1,980 citations

Journal ArticleDOI
TL;DR: Application of resilience using an educational and practical framework provides a means for connecting with and nurturing a client's resilience, which is the force that drives a person to grow through adversity and disruptions.
Abstract: Resiliency and resilience theory is presented as three waves of resiliency inquiry. The identification of resilient qualities was the first wave characterized through phenomenological identification of developmental assets and protective factors. The second wave described resilience as a disruptive and reintegrative process for accessing resilient qualities. The third wave exemplified the postmodern and multidisciplinary view of resilience, which is the force that drives a person to grow through adversity and disruptions. Application of resilience using an educational and practical framework provides a means for connecting with and nurturing a client's resilience. Practical paradigms of resiliency that empower client control and choice are suggested.

1,979 citations

Journal ArticleDOI
TL;DR: These recommendations address the best approaches for antibiotic stewardship programs to influence the optimal use of antibiotics.
Abstract: Evidence-based guidelines for implementation and measurement of antibiotic stewardship interventions in inpatient populations including long-term care were prepared by a multidisciplinary expert panel of the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. The panel included clinicians and investigators representing internal medicine, emergency medicine, microbiology, critical care, surgery, epidemiology, pharmacy, and adult and pediatric infectious diseases specialties. These recommendations address the best approaches for antibiotic stewardship programs to influence the optimal use of antibiotics.

1,969 citations


Authors

Showing all 53431 results

NameH-indexPapersCitations
Bert Vogelstein247757332094
George M. Whitesides2401739269833
Hongjie Dai197570182579
Robert M. Califf1961561167961
Frank E. Speizer193636135891
Yusuke Nakamura1792076160313
David L. Kaplan1771944146082
Marc G. Caron17367499802
George M. Church172900120514
Steven P. Gygi172704129173
Lily Yeh Jan16246773655
Tobin J. Marks1591621111604
David W. Bates1591239116698
Alfred L. Goldberg15647488296
Charles M. Perou156573202951
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023203
2022769
20217,363
20207,015
20196,309
20185,651