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Institution

University of Valencia

EducationValencia, Spain
About: University of Valencia is a education organization based out in Valencia, Spain. It is known for research contribution in the topics: Population & Neutrino. The organization has 27096 authors who have published 65669 publications receiving 1765689 citations. The organization is also known as: Universitat de València & UV.


Papers
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Journal ArticleDOI
TL;DR: In this article, a finite-range density functional was used to investigate the energy and structural properties of mixed helium clusters and the possibility of doping the cluster with a molecule of sulfur hexafluoride is also considered.
Abstract: Using a finite-range density functional, we have investigated the energetics and structural features of mixed helium clusters. The possibility of doping the cluster with a molecule of sulfur hexafluoride is also considered. It is seen that the repulsion introduced by the impurity strongly modifies the properties of the smallest drops. Although only a qualitative comparison is possible, the gross features displayed by our calculations are in agreement with recent experimental findings. {copyright} {ital 1997} {ital The American Physical Society}

293 citations

Journal ArticleDOI
TL;DR: Because there are no advantages to resuscitation with 100% oxygen, room air may be preferred under certain circumstances for the resuscitation of asphyxiated neonates.

293 citations

Journal ArticleDOI
TL;DR: It is demonstrated that TPM 100 mg/d is effective in migraine prophylaxis and was better tolerated than TPM 200mg/d, and was generally comparable to PROP.
Abstract: Topiramate (TPM) has shown efficacy in migraine prophylaxis in two large placebo-controlled, dose-ranging trials. We conducted a randomised, double-blind, multicentre trial to evaluate the efficacy and safety of two doses of topiramate vs placebo for migraine prophylaxis, with propranolol (PROP) as an active control. Subjects with episodic migraine with and without aura were randomised to TPM 100 mg/d, TPM 200 mg/d, PROP 160 mg/d (active control), or placebo. The primary efficacy measure was the change in mean monthly migraine frequency from the baseline phase relative to the double-blind treatment phase. Five hundred and seventy-five subjects were enrolled from 61 centres in 13 countries. TPM 100 mg/d was superior to placebo as measured by reduction in monthly migraine frequency, overall 50% responder rate, reduction in monthly migraine days, and reduction in the rate of daily rescue medication use. The TPM 100 mg/d and PROP groups were similar with respect to reductions in migraine frequency, responder rate, migraine days, and daily rescue medication usage. TPM 100 mg/d was better tolerated than TPM 200 mg/d, and was generally comparable to PROP. No unusual or unexpected safety risks emerged. These findings demonstrate that TPM 100 mg/d is effective in migraine prophylaxis. TPM 100 mg/d and PROP 160 mg/d exhibited similar efficacy profiles.

293 citations

Journal ArticleDOI
TL;DR: It is shown that allNT-3 null mutants have a similar phenotype and lose all neurons in the basal turn of the cochlea, suggesting that the pattern of expression of neurotrophins rather than their receptors is essential for the spatial loss of spiral sensory neurons in NT-3null mutants.
Abstract: Previous work suggested qualitatively different effects of neurotrophin 3 (NT-3) in cochlear innervation patterning in different null mutants We now show that all NT-3 null mutants have a similar phenotype and lose all neurons in the basal turn of the cochlea To understand these longitudinal deficits in neurotrophin mutants, we have compared the development of the deficit in the NT-3 mutant to the spatial-temporal expression patterns of brain-derived neurotrophic factor (BDNF) and NT-3, using lacZ reporters in each gene and with expression of the specific neurotrophin receptors, trkB and trkC In the NT-3 mutant, almost normal numbers of spiral ganglion neurons form, but fiber outgrowth to the basal turn is eliminated by embryonic day (E) 135 Most neurons are lost between E135 and E155 During the period preceding apoptosis, NT-3 is expressed in supporting cells, whereas BDNF is expressed mainly in hair cells, which become postmitotic in an apical to basal temporal gradient During the period of neuronal loss, BDNF is absent from the basal cochlea, accounting for the complete loss of basal turn neurons in the NT-3 mutant The spatial gradients of neuronal loss in these two mutants appear attributable to spatial-temporal gradients of neurotrophin expression Our immunocytochemical data show equal expression of their receptors, TrkB and TrkC, in spiral sensory neurons and thus do not relate to the basal turn loss Mice in which NT-3 was replaced by BDNF show a qualitative normal pattern of innervation at E135 This suggests that the pattern of expression of neurotrophins rather than their receptors is essential for the spatial loss of spiral sensory neurons in NT-3 null mutants

291 citations

Journal ArticleDOI
TL;DR: In this article, the authors investigated long-term changes in soil hydrological properties and erodibility during the regrowth of different types and densities of vegetation following a severe wildfire in the Serra Grossa Range, eastern Spain.
Abstract: The present study investigates long-term changes in soil hydrological properties and erodibility during the regrowth of different types and densities of vegetation following a severe wildfire in the Serra Grossa Range, eastern Spain. Twelve plots of similar slope and soil characteristics, naturally recolonized by four different plant species (trees, herbs, shrubs and dwarf shrubs) were examined using rainfall simulations during an 11-year period. The mean erosion rate was 80 g m−2 h−1, 6 months after the fire under wet-winter conditions, declining to 30 g m−2 h−1 in the following summer and reaching <10 g m−2 h−1 after 2 years. Considerable variation under the different vegetation types was observed. Herbs and shrubs reduced erosion and overland flow coefficients to negligible values 2 years after fire, whereas under trees and dwarf shrubs, appreciable overland flow and soil loss still occurred after 5 years. On tree-covered plots (Pinus halepensis), overland flow actually increased over time in association with the development of topsoil hydrophobicity, reaching a coefficient of 27% 10 years after burning. Rates of post-fire overland flow and erosion reduction were strongly influenced not only by vegetation coverage but also by the type of cover and its effects on soil hydrophobicity.

291 citations


Authors

Showing all 27402 results

NameH-indexPapersCitations
H. S. Chen1792401178529
Alvaro Pascual-Leone16596998251
Sabino Matarrese155775123278
Subir Sarkar1491542144614
Carlos Escobar148118495346
Marco Costa1461458105096
Carmen García139150396925
Javier Cuevas1381689103604
M. I. Martínez134125179885
Marco Aurelio Diaz134101593580
Avelino Corma134104989095
Kevin Lannon133165295436
Marina Cobal132107885437
Mogens Dam131110983717
Marcel Vos13199385194
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
20251
2023140
2022487
20214,747
20204,696
20193,996