scispace - formally typeset
Search or ask a question
Institution

University of Vermont

EducationBurlington, Vermont, United States
About: University of Vermont is a education organization based out in Burlington, Vermont, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 17592 authors who have published 38251 publications receiving 1609874 citations. The organization is also known as: UVM & University of Vermont and State Agricultural College.


Papers
More filters
Journal ArticleDOI
TL;DR: An association of CRP and fibrinogen with urinary albumin excretion in the micro Albuminuric range in type 2 diabetic and nondiabetic individuals is shown and chronic inflammation emerges as a potential mediator between microalbuminuria and macrovascular disease.

366 citations

Journal ArticleDOI
TL;DR: Elevated factor VIII and von Willebrand factor levels were common, independent, and dose-dependent risk factors for venous thromboembolism, and an elevated factor VII level was a possible risk factor.

365 citations

Journal ArticleDOI
24 Jan 2008-Lipids
TL;DR: The present method takes advantage of differences in the relative elution times between different types of FAs to determine most of the geometric and positional isomers of 16:1, 18:2 and 18:3 without a prior silver-ion separation in total milk fat.
Abstract: Milk fat is a complex mixture of geometric and positional isomers of monounsaturated and polyunsaturated, including short-, long- and branch-chain fatty acids (FAs). There has been partial success to resolve this mixture of FAs using different GC temperature programs, or a combination of GC isothermal and temperature programs. To overcome the problem associated with overlapping isomers prior silver-ion separation was recommended. However, this procedure is time consuming and not practical for routine analysis. In addition, previous methods focused mainly on the trans and cis isomers of 18:1. The present method takes advantage of differences in the relative elution times between different types of FAs. The method involved analyzing each milk fat using the same highly polar 100-m capillary column and GC instrument, and conducting two separations using temperature programs that plateau at 175 and 150 °C. The relative shift among the geometric and positional isomers at these two temperature settings was enough to permit identification of most of the trans and cis 16:1, 18:1 and 20:1, the c/t-18:2 and the c/c/t-18:3 isomers found in milk fat. The identity of these FAs was confirmed by prior separation of the total fatty acid methyl esters (FAMEs) of milk fat using Ag+-SPE columns, and comparing the fractions to the total milk fat. The Ag+-SPE technique was modified to obtain pure saturated, trans- and cis-monounsaturated and diunsaturated FAMEs. By combining the results from these two separate GC analyses, knowing the elution order, it was possible to determine most of the geometric and positional isomers of 16:1, 18:1, 20:1, 18:2 and 18:3 without a prior silver-ion separation. Only few minor FAs could not be resolved, notable the conjugated linoleic acid isomers that still required the complimentary Ag+-HPLC separation. The two GC temperature programs have been successfully used to routinely analyze most FA isomers in total milk and beef fats in about 200 min without the use of prior silver-ion separations.

365 citations

Journal ArticleDOI
TL;DR: It is reported that orexigenic AAPDs potently and selectively activate hypothalamic AMP-kinase, an action abolished in mice with deletion of histamine H1 receptors, which may afford a means of developing more effective therapeutic agents and provide insight into the hypothalamic regulation of food intake.
Abstract: The atypical antipsychotic drugs (AAPDs) have markedly enhanced the treatment of schizophrenias but their use has been hindered by the major weight gain elicited by some AAPDs. We report that orexigenic AAPDs potently and selectively activate hypothalamic AMP-kinase, an action abolished in mice with deletion of histamine H1 receptors. These findings may afford a means of developing more effective therapeutic agents and provide insight into the hypothalamic regulation of food intake.

364 citations

Journal ArticleDOI
TL;DR: The authors compared parents' ratings of behavioral and emotional problems on the Child Behavior Checklist (Achenbach, 1991; Achenbach & Rescorla, 2001) for general population samples of children age 5.
Abstract: This study compared parents' ratings of behavioral and emotional problems on the Child Behavior Checklist (Achenbach, 1991;Achenbach & Rescorla, 2001) for general population samples of children age...

364 citations


Authors

Showing all 17727 results

NameH-indexPapersCitations
Albert Hofman2672530321405
Ralph B. D'Agostino2261287229636
George Davey Smith2242540248373
Stephen V. Faraone1881427140298
Valentin Fuster1791462185164
Dennis J. Selkoe177607145825
Anders Björklund16576984268
Alfred L. Goldberg15647488296
Christopher P. Cannon1511118108906
Debbie A Lawlor1471114101123
Roger J. Davis147498103478
Andrew S. Levey144600156845
Jonathan G. Seidman13756389782
Yu Huang136149289209
Christine E. Seidman13451967895
Network Information
Related Institutions (5)
University of Minnesota
257.9K papers, 11.9M citations

97% related

Duke University
200.3K papers, 10.7M citations

96% related

University of Washington
305.5K papers, 17.7M citations

96% related

Yale University
220.6K papers, 12.8M citations

96% related

Cornell University
235.5K papers, 12.2M citations

95% related

Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202359
2022177
20211,840
20201,762
20191,653
20181,569