University of Veterinary Science

About: University of Veterinary Science is a education organization based out in Pyinmana, Myanmar. It is known for research contribution in the topics: Population & Receptor. The organization has 597 authors who have published 650 publications receiving 14262 citations.

Effect of various levels of T-2 toxin in the immune system of growing pigs.

Abstract: Four groups of seven-week-old pigs weighing about 9 kg were fed for three weeks a prestarter that contained 0.5, 1.0, 2.0 or 3.0 mg/kg of highly purified T-2 toxin. The average daily intakes of toxin by the pigs were 0.38, 0.81, 1.24 and 1.43 mg, respectively. The experimental and control pigs were immunised with 5 ml aluminum hydroxide gel-absorbed purified horse globulin on the first and fourth days of the treatment period. Blood samples were withdrawn on days 7, 14 and 21 and used for the determination of the titre of anti-horse globulin antibody, for an in vitro lymphocyte proliferation test, using purified horse globulin, phytohaemagglutinin and concanavalin-A and for determinations of the immune complex, the cytotoxic reaction and the phagocytic activity and phagocytic index of circulating granulocytes. The samples taken on day 21 were also used to determine the erythrocyte count, the mean cell volume of the erythrocytes, the haematocrit, the blood haemoglobin concentration, the leucocyte count and the proportion of T lymphocytes. At the end of the experiment samples were taken from the thymus, spleen and mesenteric lymph nodes for histological examination. The diets that contained 2 and 3 mg T-2 toxin/kg caused a significant decrease in the red blood cell count, the mean corpuscular volume and the haemoglobin concentration. A significant decrease in the leucocyte count and the proportion of T lymphocytes was observed in all the treatment groups. There were also dose-dependent, significant decreases in antibody formation and in the blastogenic transformation of lymphocytes, and mild to moderate reactive processes were observed histologically in the lymphoid organs.

Effects of Volatile Fatty Acids on the Epithelial Cell Proliferation of the Digestive Tract and Its Hormonal Mediation

Abstract: Publisher Summary The stratified, horny lining epithelium of the rumen has important physiological functions—such as absorption, transport, metabolic activity, and protection—that presuppose its integrity and ready adaptation to the internal and external environment. One of the main characteristics of rumen adaptation is the changed rate of mucosal cell division, and studies on the factors influencing mitosis may either directly or indirectly throw light on the underlying mechanism. The gastrointestinal mucosal membranes of ruminants adapt themselves mainly to the diet and to the mode and times of feeding. Certain feed components and their fermentation products have an appreciable influence on cell division. An analysis of the interrelationships between diet changes and rumen adaptation presents a feasible approach to the problem. The regressive and progressive changes of the rumen mucosa occur depending on the amount of easily digestible carbohydrate in the diet.