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Institution

University of Victoria

EducationVictoria, British Columbia, Canada
About: University of Victoria is a education organization based out in Victoria, British Columbia, Canada. It is known for research contribution in the topics: Population & Galaxy. The organization has 14994 authors who have published 41051 publications receiving 1447972 citations. The organization is also known as: Victoria College.


Papers
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Journal ArticleDOI
TL;DR: In this article, a deep photometric survey of the Andromeda galaxy, conducted with the wide-field cameras of the CFHT and INT telescopes, is presented, which covers the inner 50kpc of the galaxy and the Southern quadrant out to a projected distance of ∼ 150kpc.
Abstract: We present a deep photometric survey of the Andromeda galaxy, conducted with the wide-field cameras of the CFHT and INT telescopes. The surveyed area covers the inner 50kpc of the galaxy and the Southern quadrant out to a projected distance of ∼ 150kpc. A survey extension to M33 at > 200kpc probes the interface between the halos of these two galaxies. This survey is the first systematic panoramic study of this very outermost region of galaxies. We detect a multitude of largescale structures of low surface brightness, including several streams. Significant variations in stellar populations due to intervening stream-like structures are detected in the inner halo along the minor axis. This, together with the fact that the light profile between 0 ◦ .5 < R < 1 ◦ .3 follows the exponential “extended disk”, is particularly important in shedding light on the mixed and sometimes conflicting results reported in previous studies. Two new relatively luminous (MV ∼ −9) dwarf galaxies And XV and XVI are found in the study; And XVI is a particularly interesting specimen being located 270kpc in front of M31, towards the Milky Way. Underlying the many substructures that we have uncovered lies a faint, smooth and extremely extended halo component, reaching out to 150 kpc, whose stellar populations are predominantly metal-poor. This is consistent with recent claims based on spectroscopy of a small sample of stars. We find that the smooth halo component in M31 has a radially-decreasing profile that can be fit with a Hernquist model of immense scale radius ∼ 55kpc, almost a factor

414 citations

Journal ArticleDOI
28 Nov 2017-JAMA
TL;DR: Among adults with RCDI, FMT via oral capsules was not inferior to delivery by colonoscopy for preventing recurrent infection over 12 weeks and treatment with oral capsules may be an effective approach to treating RCDi.
Abstract: Importance Fecal microbiota transplantation (FMT) is effective in preventing recurrentClostridium difficileinfection (RCDI). However, it is not known whether clinical efficacy differs by route of delivery. Objective To determine whether FMT by oral capsule is noninferior to colonoscopy delivery in efficacy. Design, Setting, and Participants Noninferiority, unblinded, randomized trial conducted in 3 academic centers in Alberta, Canada. A total of 116 adult patients with RCDI were enrolled between October 2014 and September 2016, with follow-up to December 2016. The noninferiority margin was 15%. Interventions Participants were randomly assigned to FMT by capsule or by colonoscopy at a 1:1 ratio. Main Outcomes and Measures The primary outcome was the proportion of patients without RCDI 12 weeks after FMT. Secondary outcomes included (1) serious and minor adverse events, (2) changes in quality of life by the 36-Item Short Form Survey on a scale of 0 (worst possible quality of life) to 100 (best quality of life), and (3) patient perception on a scale of 1 (not at all unpleasant) to 10 (extremely unpleasant) and satisfaction on a scale of 1 (best) to 10 (worst). Results Among 116 patients randomized (mean [SD] age, 58 [19] years; 79 women [68%]), 105 (91%) completed the trial, with 57 patients randomized to the capsule group and 59 to the colonoscopy group. In per-protocol analysis, prevention of RCDI after a single treatment was achieved in 96.2% in both the capsule group (51/53) and the colonoscopy group (50/52) (difference, 0%; 1-sided 95% CI, −6.1% to infinity;P Conclusions and Relevance Among adults with RCDI, FMT via oral capsules was not inferior to delivery by colonoscopy for preventing recurrent infection over 12 weeks. Treatment with oral capsules may be an effective approach to treating RCDI. Trial Registration clinicaltrials.gov Identifier:NCT02254811

414 citations

Journal ArticleDOI
Georges Aad1, Brad Abbott2, Jalal Abdallah3, S. Abdel Khalek4  +2815 moreInstitutions (169)
TL;DR: In this article, a search for new phenomena in final states with an energetic jet and large missing transverse momentum was performed using 20.3 fb(-1) of root s = 8 TeV data collected in 2012.
Abstract: Results of a search for new phenomena in final states with an energetic jet and large missing transverse momentum are reported. The search uses 20.3 fb(-1) of root s = 8 TeV data collected in 2012 ...

414 citations

Journal ArticleDOI
Adrian John Bevan1, B. Golob2, Th. Mannel3, S. Prell4  +2061 moreInstitutions (171)
TL;DR: The physics of the SLAC and KEK B Factories are described in this paper, with a brief description of the detectors, BaBar and Belle, and data taking related issues.
Abstract: This work is on the Physics of the B Factories. Part A of this book contains a brief description of the SLAC and KEK B Factories as well as their detectors, BaBar and Belle, and data taking related issues. Part B discusses tools and methods used by the experiments in order to obtain results. The results themselves can be found in Part C.

413 citations

Journal ArticleDOI
08 Jan 2015-Nature
TL;DR: Genomic comparison with B. thetaiotaomicron in conjunction with cell culture studies show that a cohort of highly successful members of the microbiota has evolved to consume sterically-restricted yeast glycans, an adaptation that may reflect the incorporation of eukaryotic microorganisms into the human diet.
Abstract: Yeasts, which have been a component of the human diet for at least 7,000 years, possess an elaborate cell wall α-mannan The influence of yeast mannan on the ecology of the human microbiota is unknown Here we show that yeast α-mannan is a viable food source for the Gram-negative bacterium Bacteroides thetaiotaomicron, a dominant member of the microbiota Detailed biochemical analysis and targeted gene disruption studies support a model whereby limited cleavage of α-mannan on the surface generates large oligosaccharides that are subsequently depolymerized to mannose by the action of periplasmic enzymes Co-culturing studies showed that metabolism of yeast mannan by B thetaiotaomicron presents a 'selfish' model for the catabolism of this difficult to breakdown polysaccharide Genomic comparison with B thetaiotaomicron in conjunction with cell culture studies show that a cohort of highly successful members of the microbiota has evolved to consume sterically-restricted yeast glycans, an adaptation that may reflect the incorporation of eukaryotic microorganisms into the human diet

413 citations


Authors

Showing all 15188 results

NameH-indexPapersCitations
Jie Zhang1784857221720
D. M. Strom1763167194314
Sw. Banerjee1461906124364
Robert J. Glynn14674888387
Manel Esteller14671396429
R. Kowalewski1431815135517
Paul Jackson141137293464
Mingshui Chen1411543125369
Ali Khademhosseini14088776430
Roger Jones138998114061
Tord Ekelof137121291105
L. Köpke13695081787
M. Morii1341664102074
Arnaud Ferrari134139287052
Richard Brenner133110887426
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202379
2022348
20212,108
20202,200
20192,212
20181,926