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Institution

University of Virginia

EducationCharlottesville, Virginia, United States
About: University of Virginia is a education organization based out in Charlottesville, Virginia, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 52543 authors who have published 113268 publications receiving 5220506 citations. The organization is also known as: U of V & UVa.


Papers
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Journal ArticleDOI
TL;DR: Corporate brand management is a dynamic process that involves keeping up with continuous adjustments of vision, culture and image as discussed by the authors, and it is important to bring the whole corporation into corporate branding.
Abstract: This paper describes corporate branding as an organisational tool whose successful application depends on attending to the strategic, organisational and communicational context in which it is used A model to help managers analyse context in terms of the alignment between strategic vision, organisational culture and corporate image is presented The model is based on a gap analysis, which enables managers to assess the coherence of their corporate brand Use of the model is illustrated by examining the stages of development that British Airways passed through in the creation of its corporate brand The paper concludes that corporate brand management is a dynamic process that involves keeping up with continuous adjustments of vision, culture and image The model suggests an approach to corporate branding that is organisationally integrated and cross‐functional, hence the thesis that it is important to bring the (whole) corporation into corporate branding

808 citations

Journal ArticleDOI
24 Feb 2005-Nature
TL;DR: The genome of E. histolytica is presented, which reveals a variety of metabolic adaptations shared with two other amitochondrial protist pathogens: Giardia lamblia and Trichomonas vaginalis, and provides new insights into the workings and genome evolution of a major human pathogen.
Abstract: Entamoeba histolytica is an intestinal parasite and the causative agent of amoebiasis, which is a significant source of morbidity and mortality in developing countries. Here we present the genome of E. histolytica, which reveals a variety of metabolic adaptations shared with two other amitochondrial protist pathogens: Giardia lamblia and Trichomonas vaginalis. These adaptations include reduction or elimination of most mitochondrial metabolic pathways and the use of oxidative stress enzymes generally associated with anaerobic prokaryotes. Phylogenomic analysis identifies evidence for lateral gene transfer of bacterial genes into the E. histolytica genome, the effects of which centre on expanding aspects of E. histolytica's metabolic repertoire. The presence of these genes and the potential for novel metabolic pathways in E. histolytica may allow for the development of new chemotherapeutic agents. The genome encodes a large number of novel receptor kinases and contains expansions of a variety of gene families, including those associated with virulence. Additional genome features include an abundance of tandemly repeated transfer-RNA-containing arrays, which may have a structural function in the genome. Analysis of the genome provides new insights into the workings and genome evolution of a major human pathogen.

808 citations

Journal ArticleDOI
TL;DR: In this paper, the erosion rate was proportional to the 4/9ths power of drainage area and the 2/3rds power of gradient in sand-bed alluvial channels.
Abstract: Stripping of the vegetation and soil from a 13-hectare site in Virginia underlain by coastal plain sediments created a rapidly evolving badland topography. Two types of channels developed: (1) sand-bed alluvial channels were graded to transport the bed material load supplied from slope erosion with available runoff, but they also generally eroded their beds slowly, and (2) steeper, bedrock-floored channels incised rapidly. In bedrock channels the erosion rate was proportional to the 4/9ths power of drainage area and the 2/3rds power of gradient. These exponents are consistent with a model in which the erosion rate is proportional to the bed shear during high flows. Due to rapid mass wasting and reduced runoff, the alluvial channels became as much as 50% steeper during the winter than the summer, with an attendant yearly cycle of winter aggradation and summer entrenchment. The gradients, their seasonal variability, and their downstream hydraulic geometry were consistent with the predictions of total load transport formulas for sand beds and high loads. The hydraulic geometry of alluvial channels in the Virginia badlands were similar to that on the Morrison Formation in the western United States.

808 citations

Posted Content
TL;DR: In this paper, the authors investigate how the investment horizon of a firm's institutional shareholders impacts the market for corporate control and find that target firms with short-term shareholders are more likely to receive an acquisition bid but get lower premiums.
Abstract: This paper investigates how the investment horizon of a firm's institutional shareholders impacts the market for corporate control. We find that target firms with short-term shareholders are more likely to receive an acquisition bid but get lower premiums. This effect is robust and economically significant: Targets whose shareholders hold their stocks for less four months, one standard deviation away from the average holding period of 15 months, exhibit a lower premium by 3%. In addition, we find that bidder firms with short-term shareholders experience significantly worse abnormal returns around the merger announcement, as well as higher long-run underperformance. These findings suggest that firms held by short-term investors have a weaker bargaining position in acquisitions. Weaker monitoring from short-term shareholders could allow managers to proceed with value-reducing acquisitions or to bargain for personal benefits (e.g., job security, empire building) at the expense of shareholder returns.

806 citations

Journal ArticleDOI
TL;DR: If intra-abdominal pressure rises above 25 mmHg in the early postoperative period and is associated with oliguria and normal blood pressure and cardiac index, the patient should undergo re-exploration and decompression of the abdomen.
Abstract: Acute elevation of intra-abdominal pressure above 30 mmHg caused oliguria in 11 postoperative patients. Operative re-exploration and decompression in seven patients resulted in immediate diuresis. Four patients who were not re-explored developed renal failure and died. If intra-abdominal pressure rises above 25 mmHg in the early postoperative period and is associated with oliguria and normal blood pressure and cardiac index, the patient should undergo re-exploration and decompression of the abdomen.

806 citations


Authors

Showing all 53083 results

NameH-indexPapersCitations
Joan Massagué189408149951
Michael Rutter188676151592
Gordon B. Mills1871273186451
Ralph Weissleder1841160142508
Gonçalo R. Abecasis179595230323
Jie Zhang1784857221720
John R. Yates1771036129029
John A. Rogers1771341127390
Bradley Cox1692150156200
Mika Kivimäki1661515141468
Hongfang Liu1662356156290
Carl W. Cotman165809105323
Ralph A. DeFronzo160759132993
Elio Riboli1581136110499
Dan R. Littman157426107164
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023189
2022783
20215,566
20205,600
20195,001
20184,586