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Institution

University of Virginia

EducationCharlottesville, Virginia, United States
About: University of Virginia is a education organization based out in Charlottesville, Virginia, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 52543 authors who have published 113268 publications receiving 5220506 citations. The organization is also known as: U of V & UVa.


Papers
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Journal ArticleDOI
TL;DR: Two studies show that moral judgments can be made more severe by the presence of a flash of disgust, and suggest thatmoral judgments may be grounded in affectively laden moral intuitions.
Abstract: Highly hypnotizable participants were given a posthypnotic suggestion to feel a flash of disgust whenever they read an arbitrary word. They were then asked to rate moral transgressions described in vignettes that either did or did not include the disgust-inducing word. Two studies show that moral judgments can be made more severe by the presence of a flash of disgust. These findings suggest that moral judgments may be grounded in affectively laden moral intuitions.

737 citations

Journal ArticleDOI
15 Nov 2007-Nature
TL;DR: It is shown that BAI1 functions as an engulfment receptor in both the recognition and subsequent internalization of apoptotic cells, and is a phosphatidylserine recognition receptor that can directly recruit a Rac–GEF complex to mediate the uptake of apoptosis cells.
Abstract: Apoptotic cells must be removed by phagocytes to avoid local inflammation. They expose phosphatidylserine, which is normally restricted to the inner leaflet of the plasma membrane, on their surface, acting as an 'eat-me' signal. This paper shows that the BAI1 protein is an upstream receptor for phosphatidylserine in mammalian macrophages

736 citations

Journal ArticleDOI
TL;DR: Atherosclerosis occurs in the subendothelial space (intima) of medium-sized arteries at regions of disturbed blood flow and is triggered by an interplay between endothelial dysfunction and sub-endothel lipoprotein retention as mentioned in this paper.
Abstract: Atherosclerosis occurs in the subendothelial space (intima) of medium-sized arteries at regions of disturbed blood flow and is triggered by an interplay between endothelial dysfunction and subendothelial lipoprotein retention. Over time, this process stimulates a nonresolving inflammatory response that can cause intimal destruction, arterial thrombosis, and end-organ ischemia. Recent advances highlight important cell biological atherogenic processes, including mechanotransduction and inflammatory processes in endothelial cells, origins and contributions of lesional macrophages, and origins and phenotypic switching of lesional smooth muscle cells. These advances illustrate how in-depth mechanistic knowledge of the cellular pathobiology of atherosclerosis can lead to new ideas for therapy.

736 citations

Journal ArticleDOI
TL;DR: It is shown how ecosystem service assessments can be expanded to include mental health, and a heuristic, conceptual model for doing so is provided.
Abstract: A growing body of empirical evidence is revealing the value of nature experience for mental health. With rapid urbanization and declines in human contact with nature globally, crucial decisions must be made about how to preserve and enhance opportunities for nature experience. Here, we first provide points of consensus across the natural, social, and health sciences on the impacts of nature experience on cognitive functioning, emotional well-being, and other dimensions of mental health. We then show how ecosystem service assessments can be expanded to include mental health, and provide a heuristic, conceptual model for doing so.

736 citations

Journal ArticleDOI
TL;DR: Compared with the JNC7 guideline, the 2017 ACC/AHA guideline results in a substantial increase in the prevalence of hypertension, a small increase inThe percentage of US adults recommended for antihypertensive medication, and more intensive BP lowering for many adults taking antihyertensive medication.

736 citations


Authors

Showing all 53083 results

NameH-indexPapersCitations
Joan Massagué189408149951
Michael Rutter188676151592
Gordon B. Mills1871273186451
Ralph Weissleder1841160142508
Gonçalo R. Abecasis179595230323
Jie Zhang1784857221720
John R. Yates1771036129029
John A. Rogers1771341127390
Bradley Cox1692150156200
Mika Kivimäki1661515141468
Hongfang Liu1662356156290
Carl W. Cotman165809105323
Ralph A. DeFronzo160759132993
Elio Riboli1581136110499
Dan R. Littman157426107164
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023189
2022783
20215,565
20205,600
20195,001
20184,586