Institution
University of Virginia
Education•Charlottesville, Virginia, United States•
About: University of Virginia is a education organization based out in Charlottesville, Virginia, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 52543 authors who have published 113268 publications receiving 5220506 citations. The organization is also known as: U of V & UVa.
Topics: Population, Poison control, Galaxy, Context (language use), Medicine
Papers published on a yearly basis
Papers
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TL;DR: The aim of the American Thoracic Society/European Respiratory Society Task Force on EBC was to identify the important methodological issues surrounding EBC collection and assay, to provide recommendations for the measurements and to highlight areas where further research is required.
Abstract: Collection of exhaled breath condensate (EBC) is a noninvasive method for obtaining samples from the lungs. EBC contains large number of mediators including adenosine, ammonia, hydrogen peroxide, isoprostanes, leukotrienes, nitrogen oxides, peptides and cytokines. Concentrations of these mediators are influenced by lung diseases and modulated by therapeutic interventions. Similarly EBC pH also changes in respiratory diseases. The aim of the American Thoracic Society/European Respiratory Society Task Force on EBC was to identify the important methodological issues surrounding EBC collection and assay, to provide recommendations for the measurements and to highlight areas where further research is required. Based on the currently available evidence and the consensus of the expert panel for EBC collection, the following general recommendations were put together for oral sample collection: collect during tidal breathing using a noseclip and a saliva trap; define cooling temperature and collection time (10 min is generally sufficient to obtain 1-2 mL of sample and well tolerated by patients); use inert material for condenser; do not use resistor and do not use filter between the subject and the condenser. These are only general recommendations and certain circumstances may dictate variation from them. Important areas for future research involve: ascertaining mechanisms and site of exhaled breath condensate particle formation; determination of dilution markers; improving reproducibility; employment of EBC in longitudinal studies; and determining the utility of exhaled breath condensate measures for the management of individual patients. These studies are required before recommending this technique for use in clinical practice.
1,202 citations
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TL;DR: Different layers of cross-talk between several components of this complex regulatory system are emerging, and these epigenetic circuits are the focus of this review.
1,202 citations
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Michael R. Blanton1, Matthew A. Bershady2, Bela Abolfathi3, Franco D. Albareti4 +412 more•Institutions (91)
TL;DR: SDSS-IV as mentioned in this paper is a project encompassing three major spectroscopic programs: the Mapping Nearby Galaxies at Apache Point Observatory (MaNGA), the Extended Baryon Oscillation Spectroscopic Survey (eBOSS), and the Time Domain Spectroscopy Survey (TDSS).
Abstract: We describe the Sloan Digital Sky Survey IV (SDSS-IV), a project encompassing three major spectroscopic programs. The Apache Point Observatory Galactic Evolution Experiment 2 (APOGEE-2) is observing hundreds of thousands of Milky Way stars at high resolution and high signal-to-noise ratios in the near-infrared. The Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey is obtaining spatially resolved spectroscopy for thousands of nearby galaxies (median $z\sim 0.03$). The extended Baryon Oscillation Spectroscopic Survey (eBOSS) is mapping the galaxy, quasar, and neutral gas distributions between $z\sim 0.6$ and 3.5 to constrain cosmology using baryon acoustic oscillations, redshift space distortions, and the shape of the power spectrum. Within eBOSS, we are conducting two major subprograms: the SPectroscopic IDentification of eROSITA Sources (SPIDERS), investigating X-ray AGNs and galaxies in X-ray clusters, and the Time Domain Spectroscopic Survey (TDSS), obtaining spectra of variable sources. All programs use the 2.5 m Sloan Foundation Telescope at the Apache Point Observatory; observations there began in Summer 2014. APOGEE-2 also operates a second near-infrared spectrograph at the 2.5 m du Pont Telescope at Las Campanas Observatory, with observations beginning in early 2017. Observations at both facilities are scheduled to continue through 2020. In keeping with previous SDSS policy, SDSS-IV provides regularly scheduled public data releases; the first one, Data Release 13, was made available in 2016 July.
1,200 citations
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Oregon State University1, University of Bayreuth2, University of California, Berkeley3, Climate Monitoring and Diagnostics Laboratory4, Institut national de la recherche agronomique5, University of Minnesota6, Wageningen University and Research Centre7, University of California, Davis8, University of Virginia9, Swedish University of Agricultural Sciences10, United States Department of Agriculture11, University of Antwerp12, University of Edinburgh13, Technical University of Denmark14, Duke University15, Tuscia University16, Oak Ridge National Laboratory17, University of Colorado Boulder18, Harvard University19, San Diego State University20, University of Nebraska–Lincoln21, University of Helsinki22
TL;DR: The authors compared seasonal and annual estimates of CO2 and water vapor exchange across sites in forests, grasslands, crops, and tundra that are part of an international network called FLUXNET, and investigated the responses of vegetation to environmental variables.
1,199 citations
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TL;DR: In this paper, the authors compare the observed variability to that simulated in a coupled ocean-atmosphere model, making use of both existing instrumental analyses and newly available proxy-based multi-century surface temperature estimates.
Abstract: Analyses of proxy based reconstructions of surface temperatures during the past 330 years show the existence of a distinct oscillatory mode of variability with an approximate time scale of 70 years. This variability is also seen in instrumental records, although the oscillatory nature of the variability is difficult to assess due to the short length of the instrumental record. The spatial pattern of this variability is hemispheric or perhaps even global in scale, but with particular emphasis on the Atlantic region. Independent analyses of multicentury integrations of two versions of the GFDL coupled atmosphere-ocean model also show the existence of distinct multidecadal variability in the North Atlantic region which resembles the observed pattern. The model variability involves fluctuations in the intensity of the thermohaline circulation in the North Atlantic. It is our intent here to provide a direct comparison of the observed variability to that simulated in a coupled ocean-atmosphere model, making use of both existing instrumental analyses and newly available proxy based multi-century surface temperature estimates. The analyses demonstrate a substantial agreement between the simulated and observed patterns of multidecadal variability in sea surface temperature (SST) over the North Atlantic. There is much less agreement between the model and observations for sea level pressure. Seasonal analyses of the variability demonstrate that for both the model and observations SST appears to be the primary carrier of the multidecadal signal.
1,196 citations
Authors
Showing all 53083 results
Name | H-index | Papers | Citations |
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Joan Massagué | 189 | 408 | 149951 |
Michael Rutter | 188 | 676 | 151592 |
Gordon B. Mills | 187 | 1273 | 186451 |
Ralph Weissleder | 184 | 1160 | 142508 |
Gonçalo R. Abecasis | 179 | 595 | 230323 |
Jie Zhang | 178 | 4857 | 221720 |
John R. Yates | 177 | 1036 | 129029 |
John A. Rogers | 177 | 1341 | 127390 |
Bradley Cox | 169 | 2150 | 156200 |
Mika Kivimäki | 166 | 1515 | 141468 |
Hongfang Liu | 166 | 2356 | 156290 |
Carl W. Cotman | 165 | 809 | 105323 |
Ralph A. DeFronzo | 160 | 759 | 132993 |
Elio Riboli | 158 | 1136 | 110499 |
Dan R. Littman | 157 | 426 | 107164 |