Institution
University of Virginia
Education•Charlottesville, Virginia, United States•
About: University of Virginia is a education organization based out in Charlottesville, Virginia, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 52543 authors who have published 113268 publications receiving 5220506 citations. The organization is also known as: U of V & UVa.
Topics: Population, Poison control, Galaxy, Context (language use), Medicine
Papers published on a yearly basis
Papers
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TL;DR: It is demonstrated that mTORC1 regulates SREBP by controlling the nuclear entry of lipin 1, a phosphatidic acid phosphatase, which is a key component of the m TORC1-SREBP pathway.
999 citations
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TL;DR: The first all-sky view of the Sagittarius (Sgr) dwarf galaxy mapped by M giant star tracers detected in the complete Two Micron All-Sky Survey (2MASS) was presented in this paper.
Abstract: We present the first all-sky view of the Sagittarius (Sgr) dwarf galaxy mapped by M giant star tracers detected in the complete Two Micron All-Sky Survey (2MASS) The main body is fit with a King profile of 30 deg limiting radius, but with a break in the density profile from stars in tidal tails We argue that much of the observed structure beyond the 224' core radius may be unbound as the satellite undergoes catastrophic disruption A striking, >150 deg trailing tidal tail extends from the Sgr center and arcs across the South Galactic Hemisphere A prominent leading debris arm extends from the Sgr center northward of the Galactic plane to an ~40 kpc apoGalacticon, loops towards the North Galactic Cap (NGC) and descends back towards the Galactic plane, foreshortened and covering the NGC The Sgr tails lie along a well-defined orbital plane that shows little precession, which supports the notion of a nearly spherical Galactic potential The Sun lies near the path of leading Sgr debris; thus, former Sgr stars may be near or in the solar neighborhood The number of M giants in the Sgr tails is >15% that within the King limiting radius of the Sgr center That several gigayear old M giants are so widespread along the Sgr tidal arms not only places limits on the dynamical age of these arms but poses a timing problem that bears on the recent binding energy of the Sgr core and that is naturally explained by recent and catastrophic mass loss Sgr appears to contribute >75% of the high latitude, halo M giants; no evidence for M giant tidal debris from the Magellanic Clouds is found Generally good correspondence is found between the M giant, all-sky map of the Sgr system and all previously published detections of potential Sgr debris with the exception of Sgr carbon stars -- which must be subluminous to resolve the discrepancy
998 citations
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TL;DR: The abundance and size distribution of lakes is critical to quantifying limnetic contributions to the global carbon cycle as discussed by the authors, however, estimates of global lake abundance are not accurate and are unreliable.
Abstract: An accurate description of the abundance and size distribution of lakes is critical to quantifying limnetic contributions to the global carbon cycle. However, estimates of global lake abundance are ...
996 citations
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TL;DR: Findings highlight gender-specific maturational changes of the developing brain and the need for large gender-matched samples in pediatric neuropsychiatric studies.
Abstract: Brain magnetic resonance images (MRI) of 104 healthy children and adolescents, aged 4-18, showed significant effects of age and gender on brain morphometry! Males had larger cerebral (9%) and cerebellar (8%) volumes (P = 0.01 and 0.0001, respectively). In contrast, the cerebral hemispheres and caudate showed a highly consistent rightgreater-than-left asymmetry [P < 00001 for both). All volumes demonstrated a high degree of variability. These findings highlight gender-specific maturational changes of the developing brain and the need for large gender-matched samples in pediatric neuropsychiatric studies.
996 citations
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TL;DR: In this article, a grid of radiation transfer models of axisymmetric young stellar objects (YSOs) is presented, covering a wide range of stellar masses (from 0.1 to 50 M) and evolutionary stages (from the early envelope infall stage to the late disk-only stage).
Abstract: We present a grid of radiation transfer models of axisymmetric young stellar objects (YSOs), covering a wide range of stellar masses (from 0.1 to 50 M☉) and evolutionary stages (from the early envelope infall stage to the late disk-only stage). The grid consists of 20,000 YSO models, with spectral energy distributions (SEDs) and polarization spectra computed at 10 viewing angles for each model, resulting in a total of 200,000 SEDs. We have made a careful assessment of the theoretical and observational constraints on the physical conditions of disks and envelopes in YSOs and have attempted to fully span the corresponding regions in parameter space. These models are publicly available on a dedicated Web server. In this paper we summarize the main features of our models, as well as the range of parameters explored. Having a large grid covering reasonable regions of parameter space allows us to shed light on many trends in near- and mid-IR observations of YSOs (such as changes in the spectral indices and colors of their SEDs), linking them with physical parameters (such as disk and infalling envelope parameters). In particular, we examine the dependence of the spectral indices of the model SEDs on envelope accretion rate and disk mass. In addition, we show variations of spectral indices with stellar temperature, disk inner radius, and disk flaring power for a subset of disk-only models. We also examine how changing the wavelength range of data used to calculate spectral indices affects their values. We show sample color-color plots of the entire grid as well as simulated clusters at various distances with typical Spitzer sensitivities. We find that young embedded sources generally occupy a large region of color-color space due to inclination and stellar temperature effects. Disk sources occupy a smaller region of color-color space but overlap substantially with the region occupied by embedded sources, especially in the near- and mid-IR. We identify regions in color-color space where our models indicate that only sources at a given evolutionary stage should lie. We find that, while near-IR (such as JHK) and mid-IR (such as IRAC) fluxes are useful in discriminating between stars and YSOs, and are useful for identifying very young sources, the addition of longer wavelength data such as MIPS 24 μm is extremely valuable for determining the evolutionary stage of YSOs.
992 citations
Authors
Showing all 53083 results
Name | H-index | Papers | Citations |
---|---|---|---|
Joan Massagué | 189 | 408 | 149951 |
Michael Rutter | 188 | 676 | 151592 |
Gordon B. Mills | 187 | 1273 | 186451 |
Ralph Weissleder | 184 | 1160 | 142508 |
Gonçalo R. Abecasis | 179 | 595 | 230323 |
Jie Zhang | 178 | 4857 | 221720 |
John R. Yates | 177 | 1036 | 129029 |
John A. Rogers | 177 | 1341 | 127390 |
Bradley Cox | 169 | 2150 | 156200 |
Mika Kivimäki | 166 | 1515 | 141468 |
Hongfang Liu | 166 | 2356 | 156290 |
Carl W. Cotman | 165 | 809 | 105323 |
Ralph A. DeFronzo | 160 | 759 | 132993 |
Elio Riboli | 158 | 1136 | 110499 |
Dan R. Littman | 157 | 426 | 107164 |