Institution
University of Western Australia
Education•Perth, Western Australia, Australia•
About: University of Western Australia is a education organization based out in Perth, Western Australia, Australia. It is known for research contribution in the topics: Population & Poison control. The organization has 29613 authors who have published 87405 publications receiving 3064466 citations. The organization is also known as: UWA & University of WA.
Papers published on a yearly basis
Papers
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TL;DR: A concordância entre os escores de itens individuais da escala foi avaliada pelo coeficiente estatistico Kappa, sugere that essas versoes tem utilidade clinica limitada.
Abstract: Depressao e problema de saude frequente entre idosos, embora a identificacao desses pacientes seja muitas vezes dificil na pratica clinica. Nesse sentido, a avaliacao sistematica dos individuos nessa faixa etaria pode contribuir para melhorar a deteccao dos casos de depressao. Este estudo foi desenhado com o objetivo de avaliar a confiabilidade de teste-reteste das versoes com 15, 10, 4, e 1 itens da Escala de Depressao em Geriatria (GDS). Foram selecionados 64 individuos com 60 ou mais anos de idade atendidos de forma consecutiva nos ambulatorios da Unidade de Idosos do Departamento de Saude Mental da Santa Casa de Sao Paulo entre fevereiro e maio de 1998. Todos preenchiam criterios para o diagnostico de transtorno depressivo (em remissao ou atual) de acordo com a CID-10 e apresentavam escores maiores do que 10 no Mini-Exame do Estado Mental. Eles foram avaliados duas vezes com a GDS-15, sendo as entrevistas conduzidas com intervalo de 48 a 72 horas. Cinquenta e um pacientes aceitaram participar do estudo. A concordância entre os escores de itens individuais da escala foi avaliada pelo coeficiente estatistico Kappa. Estes oscilaram entre 0,04 e 0,49, indicando baixa estabilidade na resposta dos pacientes. Os escores totais da GDS-15 mantiveram-se relativamente estaveis durante o reteste, conforme indicado pelo teste pareado de Wilcoxon (z=1,60; p=0,109), correlacao de Spearman (rho=0,86; p<0,001), e Kappa ponderado (Kappa=0,64). O mesmo padrao foi observado para a GDS-10 no teste de Wilcoxon (z=0,85; p=0,402), Spearman (rho=0,81; p<0,001), e Kappa ponderado (Kappa=0,60). O escore total da GDS-4 mostrou variacoes significativas do teste para o reteste (z=3,75; p<0,001; rho=0,56; p<0,001; Kappa=0,37). Esses resultados indicam que as versoes com 1 e 4 itens apresentam baixos coeficientes de confiabilidade. Isso sugere que essas versoes tem utilidade clinica limitada. Por outro lado, a GDS com 15 e 10 iitens pode ser utilizada com relativa confiabilidade na pratica clinica, particularmente quando se consideram os escores totais das escalas.
729 citations
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Evangelos Evangelou1, Evangelos Evangelou2, Helen R. Warren3, Helen R. Warren4 +338 more•Institutions (93)
TL;DR: In this article, the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of European ancestry was conducted.
Abstract: High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of European ancestry We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also highlight shared genetic architecture between blood pressure and lifestyle exposures Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future
728 citations
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TL;DR: This paper presents the development of a framework of the potential environmental influences on walking and cycling based on published evidence and policy literature, interviews with experts and a Delphi study, and the perceived relative importance of these factors.
725 citations
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TL;DR: In this article, the authors analyze the statistical properties of Bitcoin and find that it is uncorrelated with traditional asset classes such as stocks, bonds and commodities both in normal times and in periods of financial turmoil.
725 citations
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TL;DR: In this article, the authors report SHRIMP (sensitive high-resolution ion microprobe) evidence that suggests a Grenvillian continental collision in south China, including (1) evidence for 1.3-1.0 Ga metamorphism on both sides of the Sibao orogen between the Yangtze and Cathaysia blocks and (2) sedimentary provenance of possible foreland basins that were derived from the cathaysia block and the sibao block during the continental collision.
Abstract: The timing of continental collision between the Yangtze and Cathaysia blocks of south China is an issue that bears on the accretion of Asia, as well as on the assembly and configuration of the Neoproterozoic supercontinent Rodinia. We report in this paper SHRIMP (sensitive high-resolution ion microprobe) evidence that suggests a Grenvillian continental collision in south China, including (1) evidence for 1.3–1.0 Ga metamorphism on both sides of the Sibao orogen between the Yangtze and Cathaysia blocks and (2) sedimentary provenance of possible foreland-basin deposits on the Yangtze side of the orogen that were derived from the Cathaysia block and the Sibao orogen during the continental collision. The occurrence of ca. 1430 Ma granodiorites in southern Cathaysia, along with ca. 1800 Ma basement and Archean protoliths in northern Cathaysia, makes Cathaysia a possible western extension of the Mojave province in southwestern Laurentia. Together with regional data, we suggest that the Sibao orogen could be one of the Grenvillian sutures at the center of Rodinia assembly that brought Australia, Yangtze, and Cathaysia-Laurentia together by ca. 1000 Ma.
723 citations
Authors
Showing all 29972 results
Name | H-index | Papers | Citations |
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Nicholas G. Martin | 192 | 1770 | 161952 |
Cornelia M. van Duijn | 183 | 1030 | 146009 |
Kay-Tee Khaw | 174 | 1389 | 138782 |
Steven N. Blair | 165 | 879 | 132929 |
David W. Bates | 159 | 1239 | 116698 |
Mark E. Cooper | 158 | 1463 | 124887 |
David Cameron | 154 | 1586 | 126067 |
Stephen T. Holgate | 142 | 870 | 82345 |
Jeremy K. Nicholson | 141 | 773 | 80275 |
Xin Chen | 139 | 1008 | 113088 |
Graeme J. Hankey | 137 | 844 | 143373 |
David Stuart | 136 | 1665 | 103759 |
Joachim Heinrich | 136 | 1309 | 76887 |
Carlos M. Duarte | 132 | 1173 | 86672 |
David Smith | 129 | 2184 | 100917 |