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Institution

University of Western Australia

EducationPerth, Western Australia, Australia
About: University of Western Australia is a education organization based out in Perth, Western Australia, Australia. It is known for research contribution in the topics: Population & Poison control. The organization has 29613 authors who have published 87405 publications receiving 3064466 citations. The organization is also known as: UWA & University of WA.


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Journal ArticleDOI
B. P. Abbott1, Richard J. Abbott2, T. D. Abbott, Fausto Acernese3  +1157 moreInstitutions (70)
TL;DR: In this paper, the authors improved initial estimates of the binary's properties, including component masses, spins, and tidal parameters, using the known source location, improved modeling, and recalibrated Virgo data.
Abstract: On August 17, 2017, the Advanced LIGO and Advanced Virgo gravitational-wave detectors observed a low-mass compact binary inspiral. The initial sky localization of the source of the gravitational-wave signal, GW170817, allowed electromagnetic observatories to identify NGC 4993 as the host galaxy. In this work, we improve initial estimates of the binary's properties, including component masses, spins, and tidal parameters, using the known source location, improved modeling, and recalibrated Virgo data. We extend the range of gravitational-wave frequencies considered down to 23 Hz, compared to 30 Hz in the initial analysis. We also compare results inferred using several signal models, which are more accurate and incorporate additional physical effects as compared to the initial analysis. We improve the localization of the gravitational-wave source to a 90% credible region of 16 deg2. We find tighter constraints on the masses, spins, and tidal parameters, and continue to find no evidence for nonzero component spins. The component masses are inferred to lie between 1.00 and 1.89 M when allowing for large component spins, and to lie between 1.16 and 1.60 M (with a total mass 2.73-0.01+0.04 M) when the spins are restricted to be within the range observed in Galactic binary neutron stars. Using a precessing model and allowing for large component spins, we constrain the dimensionless spins of the components to be less than 0.50 for the primary and 0.61 for the secondary. Under minimal assumptions about the nature of the compact objects, our constraints for the tidal deformability parameter Λ are (0,630) when we allow for large component spins, and 300-230+420 (using a 90% highest posterior density interval) when restricting the magnitude of the component spins, ruling out several equation-of-state models at the 90% credible level. Finally, with LIGO and GEO600 data, we use a Bayesian analysis to place upper limits on the amplitude and spectral energy density of a possible postmerger signal.

715 citations

Journal ArticleDOI
Paul M. Thompson1, Jason L. Stein2, Sarah E. Medland3, Derrek P. Hibar1  +329 moreInstitutions (96)
TL;DR: The ENIGMA Consortium has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected.
Abstract: The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) Consortium is a collaborative network of researchers working together on a range of large-scale studies that integrate data from 70 institutions worldwide. Organized into Working Groups that tackle questions in neuroscience, genetics, and medicine, ENIGMA studies have analyzed neuroimaging data from over 12,826 subjects. In addition, data from 12,171 individuals were provided by the CHARGE consortium for replication of findings, in a total of 24,997 subjects. By meta-analyzing results from many sites, ENIGMA has detected factors that affect the brain that no individual site could detect on its own, and that require larger numbers of subjects than any individual neuroimaging study has currently collected. ENIGMA's first project was a genome-wide association study identifying common variants in the genome associated with hippocampal volume or intracranial volume. Continuing work is exploring genetic associations with subcortical volumes (ENIGMA2) and white matter microstructure (ENIGMA-DTI). Working groups also focus on understanding how schizophrenia, bipolar illness, major depression and attention deficit/hyperactivity disorder (ADHD) affect the brain. We review the current progress of the ENIGMA Consortium, along with challenges and unexpected discoveries made on the way.

713 citations

Journal ArticleDOI
TL;DR: The only way to make progress in the future is to be much more clear about the meaning of the labels used for asthma and to acknowledge the assumptions associated with them, which are believed to be the most important causes of the stagnation in key clinical outcomes observed in the past 10 years.

712 citations

Journal ArticleDOI
Angela M. Wood1, Stephen Kaptoge1, Adam S. Butterworth1, Peter Willeit1, Samantha Warnakula1, Thomas Bolton1, Ellie Paige2, Dirk S. Paul1, Michael J. Sweeting1, Stephen Burgess1, Steven Bell1, William J. Astle1, David Stevens1, Albert Koulman1, Randi Selmer3, W. M. Monique Verschuren4, Shinichi Sato, Inger Njølstad5, Mark Woodward6, Mark Woodward7, Mark Woodward8, Veikko Salomaa9, Børge G. Nordestgaard10, Børge G. Nordestgaard11, Bu B. Yeap12, Bu B. Yeap13, Bu B. Yeap14, Astrid E. Fletcher15, Olle Melander16, Lewis H. Kuller17, B. Balkau18, Michael Marmot19, Wolfgang Koenig20, Wolfgang Koenig21, Edoardo Casiglia22, Cyrus Cooper23, Volker Arndt24, Oscar H. Franco25, Patrik Wennberg26, John Gallacher27, Agustín Gómez de la Cámara, Henry Völzke28, Christina C. Dahm29, Caroline Dale19, Manuela M. Bergmann, Carlos J. Crespo30, Yvonne T. van der Schouw4, Rudolf Kaaks24, Leon A. Simons31, Pagona Lagiou32, Pagona Lagiou33, Josje D. Schoufour25, Jolanda M. A. Boer, Timothy J. Key6, Beatriz L. Rodriguez34, Conchi Moreno-Iribas, Karina W. Davidson35, James O. Taylor, Carlotta Sacerdote, Robert B. Wallace36, J. Ramón Quirós, Rosario Tumino, Dan G. Blazer37, Allan Linneberg11, Makoto Daimon38, Salvatore Panico, Barbara V. Howard39, Guri Skeie5, Timo E. Strandberg40, Timo E. Strandberg41, Elisabete Weiderpass, Paul J. Nietert42, Bruce M. Psaty43, Bruce M. Psaty44, Daan Kromhout45, Elena Salamanca-Fernández46, Stefan Kiechl, Harlan M. Krumholz47, Sara Grioni, Domenico Palli48, José María Huerta, Jackie F. Price49, Johan Sundström50, Larraitz Arriola51, Hisatomi Arima52, Hisatomi Arima53, Ruth C. Travis6, Demosthenes B. Panagiotakos54, Anna Karakatsani33, Antonia Trichopoulou33, Tilman Kühn24, Diederick E. Grobbee4, Elizabeth Barrett-Connor55, Natasja M. van Schoor56, Heiner Boeing, Kim Overvad29, Kim Overvad57, Jussi Kauhanen58, Nicholas J. Wareham1, Claudia Langenberg1, Nita G. Forouhi1, Maria Wennberg26, Jean-Pierre Després59, Mary Cushman60, Jackie A. Cooper19, Carlos J. Rodriguez61, Carlos J. Rodriguez62, Masaru Sakurai63, Jonathan E. Shaw64, Matthew Knuiman13, Trudy Voortman25, Christa Meisinger, Anne Tjønneland, Hermann Brenner24, Hermann Brenner65, Luigi Palmieri66, Jean Dallongeville67, Eric J. Brunner19, Gerd Assmann, Maurizio Trevisan68, Richard F. Gillum69, Ian Ford70, Naveed Sattar70, Mariana Lazo7, Simon G. Thompson1, Pietro Ferrari71, David A. Leon15, George Davey Smith72, Richard Peto6, Rod Jackson73, Emily Banks2, Emanuele Di Angelantonio1, John Danesh1 
University of Cambridge1, Australian National University2, Norwegian Institute of Public Health3, Utrecht University4, University of Tromsø5, University of Oxford6, Johns Hopkins University7, The George Institute for Global Health8, National Institutes of Health9, Copenhagen University Hospital10, University of Copenhagen11, Fiona Stanley Hospital12, University of Western Australia13, Harry Perkins Institute of Medical Research14, University of London15, Lund University16, University of Pittsburgh17, French Institute of Health and Medical Research18, University College London19, Technische Universität München20, University of Ulm21, University of Padua22, University of Southampton23, German Cancer Research Center24, Erasmus University Medical Center25, Umeå University26, Cardiff University27, Greifswald University Hospital28, Aarhus University29, Portland State University30, University of New South Wales31, Harvard University32, National and Kapodistrian University of Athens33, University of Hawaii34, Columbia University35, University of Iowa36, Duke University37, Yamagata University38, Tuskegee University39, University of Oulu40, University of Helsinki41, Medical University of South Carolina42, Kaiser Permanente43, University of Washington44, University of Groningen45, University of Granada46, Yale University47, Prevention Institute48, University of Edinburgh49, Uppsala University50, Basque Government51, Royal Prince Alfred Hospital52, Kyushu University53, Harokopio University54, University of California, San Diego55, VU University Medical Center56, Aalborg University57, University of Eastern Finland58, Laval University59, University of Vermont60, Wake Forest University61, Wake Forest Baptist Medical Center62, Kanazawa Medical University63, Baker IDI Heart and Diabetes Institute64, Heidelberg University65, Istituto Superiore di Sanità66, Pasteur Institute67, City College of New York68, Howard University69, University of Glasgow70, International Agency for Research on Cancer71, University of Bristol72, University of Auckland73
TL;DR: Current drinkers of alcohol in high-income countries, the threshold for lowest risk of all-cause mortality was about 100 g/week, and data support limits for alcohol consumption that are lower than those recommended in most current guidelines.

711 citations

Journal ArticleDOI
TL;DR: The relationship between adsorption and pH varies with the pKa, of the conjugate acid of the anion, for several adsorbents in presence of an excess of specifically adsorbed anions.
Abstract: Summary The relationship between adsorption and pH, termed the adsorption envelope, varies with the pKa, of the conjugate acid of the anion, for several adsorbents in presence of an excess of specifically adsorbed anions. At pH values where the acid is fully dissociated, specific adsorption occurs only to the extent of the positive charge of the surface and little specific adsorption is found at pH values more alkaline than the zero point of charge (zpc). With incompletely dissociated acids, anion adsorption can also take place at pH values more alkaline than the zpc providing the pH is somewhere near a pKa value of the acid, where the energy required to abstract a proton from the acid is at a minimum. The proton is required for the removal of a surface OH which provides a site for the anion. Specific anion adsorption (i) from a fully dissociated acid can reduce the positive charge of the surface to zero and (ii) from a weak acid can make even a negative surface more negative. Thus specific adsorption shifts the zpc to more acid values. The relationship between anion adsorption and OH release is not necessarily simple. The ideas proposed for anion adsorption have implications for cation adsorption and incorporation in an oxide surface.

706 citations


Authors

Showing all 29972 results

NameH-indexPapersCitations
Nicholas G. Martin1921770161952
Cornelia M. van Duijn1831030146009
Kay-Tee Khaw1741389138782
Steven N. Blair165879132929
David W. Bates1591239116698
Mark E. Cooper1581463124887
David Cameron1541586126067
Stephen T. Holgate14287082345
Jeremy K. Nicholson14177380275
Xin Chen1391008113088
Graeme J. Hankey137844143373
David Stuart1361665103759
Joachim Heinrich136130976887
Carlos M. Duarte132117386672
David Smith1292184100917
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023138
2022656
20215,967
20205,589
20195,452
20184,923