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Institution

University of Western Australia

EducationPerth, Western Australia, Australia
About: University of Western Australia is a education organization based out in Perth, Western Australia, Australia. It is known for research contribution in the topics: Population & Poison control. The organization has 29613 authors who have published 87405 publications receiving 3064466 citations. The organization is also known as: UWA & University of WA.


Papers
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Journal ArticleDOI
TL;DR: In this paper, it is shown that the annealing algorithm converges with probability arbitrarily close to 1, and that it is no better than a deterministic method. But it is also shown that there are cases where convergence takes exponentially long.
Abstract: The annealing algorithm is a stochastic optimization method which has attracted attention because of its success with certain difficult problems, including NP-hard combinatorial problems such as the travelling salesman, Steiner trees and others. There is an appealing physical analogy for its operation, but a more formal model seems desirable. In this paper we present such a model and prove that the algorithm converges with probability arbitrarily close to 1. We also show that there are cases where convergence takes exponentially long—that is, it is no better than a deterministic method. We study how the convergence rate is affected by the form of the problem. Finally we describe a version of the algorithm that terminates in polynomial time and allows a good deal of ‘practical’ confidence in the solution.

609 citations

Journal ArticleDOI
TL;DR: The burden of small-for-gestational-age births is very high in countries of low and middle income and is concentrated in south Asia.

609 citations

Journal ArticleDOI
TL;DR: It is shown that BAP1 knockdown in MPM cell lines affects E2F and Polycomb target genes, which implicate transcriptional deregulation in the pathogenesis of MPM.
Abstract: Malignant pleural mesotheliomas (MPMs) often show CDKN2A and NF2 inactivation, but other highly recurrent mutations have not been described. To identify additional driver genes, we used an integrated genomic analysis of 53 MPM tumor samples to guide a focused sequencing effort that uncovered somatic inactivating mutations in BAP1 in 23% of MPMs. The BAP1 nuclear deubiquitinase is known to target histones (together with ASXL1 as a Polycomb repressor subunit) and the HCF1 transcriptional co-factor, and we show that BAP1 knockdown in MPM cell lines affects E2F and Polycomb target genes. These findings implicate transcriptional deregulation in the pathogenesis of MPM.

608 citations

Journal ArticleDOI
TL;DR: Evidence suggests that saccades trigger two distinct neural processes: a suppression of visual sensitivity, specific to the magnocellular pathway, that dampens the sensation of motion and a gross perceptual distortion of visual space in anticipation of the repositioning of gaze.

607 citations

Journal ArticleDOI
01 Jun 2007-Lithos
TL;DR: In this paper, the ages of the Nankunshan alkaline granite and the Fogang granitic batholith are reported. But the authors do not identify the type of granites.

607 citations


Authors

Showing all 29972 results

NameH-indexPapersCitations
Nicholas G. Martin1921770161952
Cornelia M. van Duijn1831030146009
Kay-Tee Khaw1741389138782
Steven N. Blair165879132929
David W. Bates1591239116698
Mark E. Cooper1581463124887
David Cameron1541586126067
Stephen T. Holgate14287082345
Jeremy K. Nicholson14177380275
Xin Chen1391008113088
Graeme J. Hankey137844143373
David Stuart1361665103759
Joachim Heinrich136130976887
Carlos M. Duarte132117386672
David Smith1292184100917
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023138
2022656
20215,967
20205,589
20195,452
20184,923