Institution
University of Western Australia
Education•Perth, Western Australia, Australia•
About: University of Western Australia is a education organization based out in Perth, Western Australia, Australia. It is known for research contribution in the topics: Population & Poison control. The organization has 29613 authors who have published 87405 publications receiving 3064466 citations. The organization is also known as: UWA & University of WA.
Papers published on a yearly basis
Papers
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TL;DR: In this paper, it is shown that the annealing algorithm converges with probability arbitrarily close to 1, and that it is no better than a deterministic method. But it is also shown that there are cases where convergence takes exponentially long.
Abstract: The annealing algorithm is a stochastic optimization method which has attracted attention because of its success with certain difficult problems, including NP-hard combinatorial problems such as the travelling salesman, Steiner trees and others. There is an appealing physical analogy for its operation, but a more formal model seems desirable. In this paper we present such a model and prove that the algorithm converges with probability arbitrarily close to 1. We also show that there are cases where convergence takes exponentially long—that is, it is no better than a deterministic method. We study how the convergence rate is affected by the form of the problem. Finally we describe a version of the algorithm that terminates in polynomial time and allows a good deal of ‘practical’ confidence in the solution.
609 citations
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Johns Hopkins University1, Brigham and Women's Hospital2, University of London3, World Health Organization4, University of Western Australia5, University of North Carolina at Chapel Hill6, Aga Khan University7, Imperial College London8, Harvard University9, Pontifical Catholic University of Chile10, Institute of Tropical Medicine Antwerp11, Ghent University12, Centers for Disease Control and Prevention13, Mahidol University14, University of KwaZulu-Natal15, University College London16, University of Los Andes17, Universidade Federal de Pelotas18, George Washington University19, Save the Children20
TL;DR: The burden of small-for-gestational-age births is very high in countries of low and middle income and is concentrated in south Asia.
609 citations
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TL;DR: It is shown that BAP1 knockdown in MPM cell lines affects E2F and Polycomb target genes, which implicate transcriptional deregulation in the pathogenesis of MPM.
Abstract: Malignant pleural mesotheliomas (MPMs) often show CDKN2A and NF2 inactivation, but other highly recurrent mutations have not been described. To identify additional driver genes, we used an integrated genomic analysis of 53 MPM tumor samples to guide a focused sequencing effort that uncovered somatic inactivating mutations in BAP1 in 23% of MPMs. The BAP1 nuclear deubiquitinase is known to target histones (together with ASXL1 as a Polycomb repressor subunit) and the HCF1 transcriptional co-factor, and we show that BAP1 knockdown in MPM cell lines affects E2F and Polycomb target genes. These findings implicate transcriptional deregulation in the pathogenesis of MPM.
608 citations
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TL;DR: Evidence suggests that saccades trigger two distinct neural processes: a suppression of visual sensitivity, specific to the magnocellular pathway, that dampens the sensation of motion and a gross perceptual distortion of visual space in anticipation of the repositioning of gaze.
607 citations
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TL;DR: In this paper, the ages of the Nankunshan alkaline granite and the Fogang granitic batholith are reported. But the authors do not identify the type of granites.
607 citations
Authors
Showing all 29972 results
Name | H-index | Papers | Citations |
---|---|---|---|
Nicholas G. Martin | 192 | 1770 | 161952 |
Cornelia M. van Duijn | 183 | 1030 | 146009 |
Kay-Tee Khaw | 174 | 1389 | 138782 |
Steven N. Blair | 165 | 879 | 132929 |
David W. Bates | 159 | 1239 | 116698 |
Mark E. Cooper | 158 | 1463 | 124887 |
David Cameron | 154 | 1586 | 126067 |
Stephen T. Holgate | 142 | 870 | 82345 |
Jeremy K. Nicholson | 141 | 773 | 80275 |
Xin Chen | 139 | 1008 | 113088 |
Graeme J. Hankey | 137 | 844 | 143373 |
David Stuart | 136 | 1665 | 103759 |
Joachim Heinrich | 136 | 1309 | 76887 |
Carlos M. Duarte | 132 | 1173 | 86672 |
David Smith | 129 | 2184 | 100917 |