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Institution

University of Westminster

EducationLondon, United Kingdom
About: University of Westminster is a education organization based out in London, United Kingdom. It is known for research contribution in the topics: Population & Politics. The organization has 2944 authors who have published 8426 publications receiving 200236 citations. The organization is also known as: Westminster University & Royal Polytechnic Institution.


Papers
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Journal ArticleDOI
TL;DR: Despite some useful progress being made in relation to strengthening the evidence base for IPE, the paper concludes by stressing that further rigorous mixed method studies are needed to provide a greater clarity of IPE and its effects on professional practice and patient/client care.
Abstract: Over the past decade systematic reviews of interprofessional education (IPE) have provided a more informed understanding of the effects of this type of education. This paper contributes to this literature by reporting an update of a Cochrane systematic review published in this journal ten years ago (Zwarenstein et al., 1999 ). In updating this initial review, our current work involved searches of a number of electronic databases from 1999-2006, as well as reference lists, books, conference proceedings and websites. Like the previous review, only studies which employed randomized controlled trials, controlled-before and-after-studies and interrupted time series studies of IPE, and that reported validated professional practice and health care outcomes, were included. While the first review found no studies which met its inclusion criteria, the updated review located six IPE studies. This paper aims to add to the ongoing development of evidence for IPE. Despite some useful progress being made in relation to strengthening the evidence base for IPE, the paper concludes by stressing that further rigorous mixed method studies of IPE are needed to provide a greater clarity of IPE and its effects on professional practice and patient/client care.

350 citations

Journal ArticleDOI
Urmo Võsa1, Annique Claringbould2, Annique Claringbould3, Harm-Jan Westra1, Marc Jan Bonder1, Patrick Deelen, Biao Zeng4, Holger Kirsten5, Ashis Saha6, Roman Kreuzhuber2, Roman Kreuzhuber7, Roman Kreuzhuber8, Seyhan Yazar9, Harm Brugge1, Roy Oelen1, Dylan H. de Vries1, Monique G. P. van der Wijst1, Silva Kasela10, Natalia Pervjakova10, Isabel Alves11, Marie-Julie Favé11, Mawusse Agbessi11, Mark W. Christiansen12, Rick Jansen13, Ilkka Seppälä, Lin Tong14, Alexander Teumer15, Katharina Schramm16, Gibran Hemani17, Joost Verlouw18, Hanieh Yaghootkar19, Hanieh Yaghootkar20, Hanieh Yaghootkar21, Reyhan Sönmez Flitman22, Reyhan Sönmez Flitman23, Andrew A. Brown24, Andrew A. Brown25, Viktorija Kukushkina10, Anette Kalnapenkis10, Sina Rüeger23, Eleonora Porcu23, Jaanika Kronberg10, Johannes Kettunen, Bernett Lee26, Futao Zhang27, Ting Qi27, Jose Alquicira Hernandez9, Wibowo Arindrarto28, Frank Beutner5, Peter A C 't Hoen29, Joyce B. J. van Meurs18, Jenny van Dongen13, Maarten van Iterson28, Morris A. Swertz, Julia Dmitrieva30, Mahmoud Elansary30, Benjamin P. Fairfax31, Michel Georges30, Bastiaan T. Heijmans28, Alex W. Hewitt32, Mika Kähönen, Yungil Kim6, Yungil Kim33, Julian C. Knight31, Peter Kovacs5, Knut Krohn5, Shuang Li1, Markus Loeffler5, Urko M. Marigorta34, Urko M. Marigorta4, Hailang Mei28, Yukihide Momozawa30, Martina Müller-Nurasyid16, Matthias Nauck15, Michel G. Nivard35, Brenda W.J.H. Penninx13, Jonathan K. Pritchard36, Olli T. Raitakari37, Olli T. Raitakari38, Olaf Rötzschke26, Eline Slagboom28, Coen D.A. Stehouwer39, Michael Stumvoll5, Patrick F. Sullivan40, Joachim Thiery5, Anke Tönjes5, Jan H. Veldink41, Uwe Völker15, Robert Warmerdam1, Cisca Wijmenga1, Morris Swertz, Anand Kumar Andiappan26, Grant W. Montgomery27, Samuli Ripatti42, Markus Perola43, Zoltán Kutalik23, Emmanouil T. Dermitzakis25, Emmanouil T. Dermitzakis22, Sven Bergmann23, Sven Bergmann22, Timothy M. Frayling19, Holger Prokisch44, Habibul Ahsan14, Brandon L. Pierce14, Terho Lehtimäki, Dorret I. Boomsma13, Bruce M. Psaty12, Sina A. Gharib12, Philip Awadalla11, Lili Milani10, Willem H. Ouwehand8, Willem H. Ouwehand45, Willem H. Ouwehand7, Kate Downes8, Kate Downes7, Oliver Stegle46, Oliver Stegle2, Alexis Battle6, Peter M. Visscher27, Jian Yang47, Jian Yang27, Markus Scholz5, Joseph E. Powell48, Joseph E. Powell9, Greg Gibson4, Tõnu Esko10, Lude Franke1 
TL;DR: In this article, the authors performed cis-and trans-expression quantitative trait locus (eQTL) analyses using blood-derived expression from 31,684 individuals through the eQTLGen Consortium.
Abstract: Trait-associated genetic variants affect complex phenotypes primarily via regulatory mechanisms on the transcriptome. To investigate the genetics of gene expression, we performed cis- and trans-expression quantitative trait locus (eQTL) analyses using blood-derived expression from 31,684 individuals through the eQTLGen Consortium. We detected cis-eQTL for 88% of genes, and these were replicable in numerous tissues. Distal trans-eQTL (detected for 37% of 10,317 trait-associated variants tested) showed lower replication rates, partially due to low replication power and confounding by cell type composition. However, replication analyses in single-cell RNA-seq data prioritized intracellular trans-eQTL. Trans-eQTL exerted their effects via several mechanisms, primarily through regulation by transcription factors. Expression of 13% of the genes correlated with polygenic scores for 1,263 phenotypes, pinpointing potential drivers for those traits. In summary, this work represents a large eQTL resource, and its results serve as a starting point for in-depth interpretation of complex phenotypes.

344 citations

Journal ArticleDOI
TL;DR: The properties of PHAs, their uses, the various attempts towards the production, focusing on the utilization of cheap substrates and the development of different fermentation strategies for the production of these polymers are described, an essential step forward towards their widespread use.
Abstract: Polyhydroxyalkanoates (PHAs) have recently been the focus of attention as a biodegradable and biocompatible substitute for conventional non degradable plastics. The cost of large-scale production of these polymers has inhibited its widespread use. Thus, economical, large-scale production of PHAs is currently being studied intensively. Various bacterial strains, either wild-type or recombinant have been utilized with a wide spectrum of utilizable carbon sources. New fermentation strategies have been developed for the efficient production of PHAs at high concentration and productivity. With the current advances, PHAs can now be produced to a concentration of 80 g L?1 with productivities greater than 4 g PHA L?1 h?1. These advances will further lower the production cost of PHAs and allow this family of polymers to become a leading biodegradable polymer in the near future. This review describes the properties of PHAs, their uses, the various attempts towards the production of PHAs, focusing on the utilization of cheap substrates and the development of different fermentation strategies for the production of these polymers, an essential step forward towards their widespread use. Copyright © 2010 Society of Chemical Industry.

341 citations

Journal ArticleDOI
TL;DR: A comprehensive study of the diurnal free cortisol cycle designed to analyse its components and to investigate their reliability and inter-relatedness is reported.

335 citations

Journal ArticleDOI
TL;DR: The main species of intestinal worms with particular attention to intestinal nematodes are introduced, and some important characteristics of an ideal study of the effects of deworming are described.
Abstract: More than a half of the world's population are infected with one or more species of intestinal worms of which the nematodes Ascaris lumbricoides, Trichuris trichiura and the hookworms are the most common and important in terms of child health. This paper: (1) introduces the main species of intestinal worms with particular attention to intestinal nematodes; (2) examines how such worms may affect child growth and nutrition; (3) reviews the biological and epidemiological factors that influence the effects that worms can have on the growth and nutrition of children; (4) considers the many factors that can affect the impact of treatment with anthelmintic drugs; (5) presents the results of a meta-analysis of studies of the effect of treating worm infections on child growth and nutrition; (6) discusses the results in terms of what is reasonable to expect that deworming alone can achieve; (7) describes some important characteristics of an ideal study of the effects of deworming; and (8) comments on the implications for programmes of recommendations concerning mass deworming.

333 citations


Authors

Showing all 3028 results

NameH-indexPapersCitations
Barbara J. Sahakian14561269190
Peter B. Jones145185794641
Andrew Steptoe137100373431
Robert West112106153904
Aldo R. Boccaccini103123454155
Kevin Morgan9565549644
Shaogang Gong9243031444
Thomas A. Buchanan9134948865
Mauro Perretti9049728463
Jimmy D. Bell8858925983
Andrew D. McCulloch7535819319
Mark S. Goldberg7323518067
Dimitrios Buhalis7231623830
Ali Mobasheri6937014642
Michael E. Boulton6933123747
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202334
2022111
2021439
2020501
2019434
2018461