Institution
University of Westminster
Education•London, United Kingdom•
About: University of Westminster is a education organization based out in London, United Kingdom. It is known for research contribution in the topics: Population & Politics. The organization has 2944 authors who have published 8426 publications receiving 200236 citations. The organization is also known as: Westminster University & Royal Polytechnic Institution.
Topics: Population, Politics, European union, Band-pass filter, Tourism
Papers published on a yearly basis
Papers
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TL;DR: Despite some useful progress being made in relation to strengthening the evidence base for IPE, the paper concludes by stressing that further rigorous mixed method studies are needed to provide a greater clarity of IPE and its effects on professional practice and patient/client care.
Abstract: Over the past decade systematic reviews of interprofessional education (IPE) have provided a more informed understanding of the effects of this type of education. This paper contributes to this literature by reporting an update of a Cochrane systematic review published in this journal ten years ago (Zwarenstein et al., 1999 ). In updating this initial review, our current work involved searches of a number of electronic databases from 1999-2006, as well as reference lists, books, conference proceedings and websites. Like the previous review, only studies which employed randomized controlled trials, controlled-before and-after-studies and interrupted time series studies of IPE, and that reported validated professional practice and health care outcomes, were included. While the first review found no studies which met its inclusion criteria, the updated review located six IPE studies. This paper aims to add to the ongoing development of evidence for IPE. Despite some useful progress being made in relation to strengthening the evidence base for IPE, the paper concludes by stressing that further rigorous mixed method studies of IPE are needed to provide a greater clarity of IPE and its effects on professional practice and patient/client care.
350 citations
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University Medical Center Groningen1, European Bioinformatics Institute2, Netherlands Cancer Institute3, Georgia Institute of Technology4, Leipzig University5, Johns Hopkins University6, University of Cambridge7, NHS Blood and Transplant8, Garvan Institute of Medical Research9, University of Tartu10, Ontario Institute for Cancer Research11, University of Washington12, Public Health Research Institute13, University of Chicago14, Greifswald University Hospital15, Ludwig Maximilian University of Munich16, University of Bristol17, Erasmus University Rotterdam18, Royal Devon and Exeter Hospital19, Luleå University of Technology20, University of Westminster21, Swiss Institute of Bioinformatics22, University of Lausanne23, University of Dundee24, University of Geneva25, Agency for Science, Technology and Research26, University of Queensland27, Leiden University Medical Center28, Radboud University Nijmegen29, University of Liège30, University of Oxford31, Menzies Research Institute32, Icahn School of Medicine at Mount Sinai33, Ikerbasque34, VU University Amsterdam35, Stanford University36, University of Turku37, Turku University Hospital38, Maastricht University39, Karolinska Institutet40, Utrecht University41, University of Helsinki42, National Institutes of Health43, Technische Universität München44, Wellcome Trust Sanger Institute45, German Cancer Research Center46, Westlake University47, University of New South Wales48
TL;DR: In this article, the authors performed cis-and trans-expression quantitative trait locus (eQTL) analyses using blood-derived expression from 31,684 individuals through the eQTLGen Consortium.
Abstract: Trait-associated genetic variants affect complex phenotypes primarily via regulatory mechanisms on the transcriptome. To investigate the genetics of gene expression, we performed cis- and trans-expression quantitative trait locus (eQTL) analyses using blood-derived expression from 31,684 individuals through the eQTLGen Consortium. We detected cis-eQTL for 88% of genes, and these were replicable in numerous tissues. Distal trans-eQTL (detected for 37% of 10,317 trait-associated variants tested) showed lower replication rates, partially due to low replication power and confounding by cell type composition. However, replication analyses in single-cell RNA-seq data prioritized intracellular trans-eQTL. Trans-eQTL exerted their effects via several mechanisms, primarily through regulation by transcription factors. Expression of 13% of the genes correlated with polygenic scores for 1,263 phenotypes, pinpointing potential drivers for those traits. In summary, this work represents a large eQTL resource, and its results serve as a starting point for in-depth interpretation of complex phenotypes.
344 citations
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TL;DR: The properties of PHAs, their uses, the various attempts towards the production, focusing on the utilization of cheap substrates and the development of different fermentation strategies for the production of these polymers are described, an essential step forward towards their widespread use.
Abstract: Polyhydroxyalkanoates (PHAs) have recently been the focus of attention as a biodegradable and biocompatible substitute for conventional non degradable plastics. The cost of large-scale production of these polymers has inhibited its widespread use. Thus, economical, large-scale production of PHAs is currently being studied intensively. Various bacterial strains, either wild-type or recombinant have been utilized with a wide spectrum of utilizable carbon sources. New fermentation strategies have been developed for the efficient production of PHAs at high concentration and productivity. With the current advances, PHAs can now be produced to a concentration of 80 g L?1 with productivities greater than 4 g PHA L?1 h?1. These advances will further lower the production cost of PHAs and allow this family of polymers to become a leading biodegradable polymer in the near future. This review describes the properties of PHAs, their uses, the various attempts towards the production of PHAs, focusing on the utilization of cheap substrates and the development of different fermentation strategies for the production of these polymers, an essential step forward towards their widespread use. Copyright © 2010 Society of Chemical Industry.
341 citations
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TL;DR: A comprehensive study of the diurnal free cortisol cycle designed to analyse its components and to investigate their reliability and inter-relatedness is reported.
335 citations
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TL;DR: The main species of intestinal worms with particular attention to intestinal nematodes are introduced, and some important characteristics of an ideal study of the effects of deworming are described.
Abstract: More than a half of the world's population are infected with one or more species of intestinal worms of which the nematodes Ascaris lumbricoides, Trichuris trichiura and the hookworms are the most common and important in terms of child health. This paper: (1) introduces the main species of intestinal worms with particular attention to intestinal nematodes; (2) examines how such worms may affect child growth and nutrition; (3) reviews the biological and epidemiological factors that influence the effects that worms can have on the growth and nutrition of children; (4) considers the many factors that can affect the impact of treatment with anthelmintic drugs; (5) presents the results of a meta-analysis of studies of the effect of treating worm infections on child growth and nutrition; (6) discusses the results in terms of what is reasonable to expect that deworming alone can achieve; (7) describes some important characteristics of an ideal study of the effects of deworming; and (8) comments on the implications for programmes of recommendations concerning mass deworming.
333 citations
Authors
Showing all 3028 results
Name | H-index | Papers | Citations |
---|---|---|---|
Barbara J. Sahakian | 145 | 612 | 69190 |
Peter B. Jones | 145 | 1857 | 94641 |
Andrew Steptoe | 137 | 1003 | 73431 |
Robert West | 112 | 1061 | 53904 |
Aldo R. Boccaccini | 103 | 1234 | 54155 |
Kevin Morgan | 95 | 655 | 49644 |
Shaogang Gong | 92 | 430 | 31444 |
Thomas A. Buchanan | 91 | 349 | 48865 |
Mauro Perretti | 90 | 497 | 28463 |
Jimmy D. Bell | 88 | 589 | 25983 |
Andrew D. McCulloch | 75 | 358 | 19319 |
Mark S. Goldberg | 73 | 235 | 18067 |
Dimitrios Buhalis | 72 | 316 | 23830 |
Ali Mobasheri | 69 | 370 | 14642 |
Michael E. Boulton | 69 | 331 | 23747 |