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Institution

University of Westminster

EducationLondon, United Kingdom
About: University of Westminster is a education organization based out in London, United Kingdom. It is known for research contribution in the topics: Population & Politics. The organization has 2944 authors who have published 8426 publications receiving 200236 citations. The organization is also known as: Westminster University & Royal Polytechnic Institution.


Papers
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Journal ArticleDOI
TL;DR: Six anti-microbial peptides were deemed potential candidates for the Chagas paratransgenic system as they were capable of killing T. cruzi at concentrations that exhibit little or no toxic effects on R. rhodnii.

60 citations

Journal ArticleDOI
TL;DR: In this article, the authors conclude the series on deregulation, updating the statistics presented in the introductory paper to cover the financial year 1994-1995, and output from the National Travel Survey 1992-94 published by the Department of Transport in 1995.

60 citations

Journal ArticleDOI
TL;DR: Differences between these conditions with a single protocol using validated objective experimental (off-vertical axis rotation, OVAR1) and validated patient-centred measures of motion sickness susceptibility are investigated.
Abstract: Motion sickness is a syndrome provoked by sensory conflict that involves the vestibular system with symptoms resembling those of common neuro-otological disorders including vestibular neuritis (VN) and vestibular migraine (VM). By contrast, it is generally believed that bilateral vestibular failure (BVF) causes reduced motion sickness susceptibility. We investigate differences between these conditions with a single protocol using validated objective experimental (off-vertical axis rotation, OVAR1) and validated patient-centred measures of motion sickness susceptibility.2 Five groups were studied: 1. Normal healthy controls ( n=12; mean age 51, SD 17.2; 4/12 women). 2. VN (history of acute vertigo without neurological features or hearing loss; none treated with steroids acutely; positive head thrust test; spontaneous unidirectional horizontal nystagmus; acute caloric canal paresis >30%, mean canal paresis repeated in chronic phase after 6 weeks was 38% (SD 31); n=12; disease duration range 10–33 months; mean age 45, SD 15.3; 5/12 women). 3. BVF (absent caloric or rotational responses; confirmed in chronic phase; n=8; mean age 51, SD 11.5; 3/8 women). 4. VM (recurrent episodic vestibular symptoms in association with migraine according to published criteria with no vestibular test abnormalities3; n=12; mean age 45, SD 15.3; 11/12 women). 5. Migraine without vestibular symptoms ( M ; recurrent headaches meeting International Headache Society (IHS) 2004 criteria; with/without aura but with no significant vestibular symptoms3; n=12; mean age 41, SD 13.6; 8/12 women. Two groups of patient with migraine were studied (one with vestibular symptoms, VM, and one without vestibular symptoms, M) to determine whether the presence of vestibular symptoms in the setting of migraine influences motion sickness susceptibility. The normal controls and the migraine group were screened for vestibular symptoms but did not undergo formal vestibular testing. Participants were …

60 citations

Journal ArticleDOI
TL;DR: It is suggested that while pH control in the cathode chamber is important, it does not guarantee sustained laccase activity; as salinity increases affect the activity and it could be mitigated using a cation selective membrane.

60 citations

Journal ArticleDOI
TL;DR: In this paper, the authors used solvent-casting to extract poly(3-hydroxyalkanoates (PHAs) blends as resorbable biomaterials for the manufacture of nerve guidance conduits.
Abstract: The only types of polyhydroxyalkanoates (PHAs) that have been explored for use in nerve regeneration are poly(3-hydroxybutyrate), P(3HB), and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (P(3HB-co-3HHx)). However, nerve regeneration induced by these PHAs is inferior to that of autologous nerve grafting. The aim of this work was to study novel PHA blends as resorbable biomaterials for the manufacture of nerve guidance conduits. PHA blend films with varying ratios of poly(3-hydroxyoctanoate)/P(3HB) (P(3HO)/P(3HB)) were produced using the solvent-casting method. Neat films of P(3HO) and P(3HB), along with 25:75, 50:50, and 75:25 blend films of P(3HO)/P(3HB), were characterized with respect to chemical, material, and biological properties. On surface analysis, the blends exhibited higher values of roughness compared with the neat films. The differential scanning calorimetry characterization of the blends confirmed that P(3HO) and P(3HB) formed immiscible blends. FTIR and XRD analysis of the blends showed a decrease in crystallinity along with an increase of the proportion of P(3HO) . However, an increase in the stiffness of the blends was observed when the proportion of P(3HB) increased. Although all of the blends were biocompatible with NG108-15 neuronal cells, the 25:75 P(3HO)/P(3HB) blend showed significantly better support for growth and differentiation of these cells. The mechanical properties of PHA blends correspond to the reported properties of peripheral nerves. Therefore, they could serve as base material for the manufacture of nerve guidance conduits.

60 citations


Authors

Showing all 3028 results

NameH-indexPapersCitations
Barbara J. Sahakian14561269190
Peter B. Jones145185794641
Andrew Steptoe137100373431
Robert West112106153904
Aldo R. Boccaccini103123454155
Kevin Morgan9565549644
Shaogang Gong9243031444
Thomas A. Buchanan9134948865
Mauro Perretti9049728463
Jimmy D. Bell8858925983
Andrew D. McCulloch7535819319
Mark S. Goldberg7323518067
Dimitrios Buhalis7231623830
Ali Mobasheri6937014642
Michael E. Boulton6933123747
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202334
2022111
2021439
2020501
2019434
2018461