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Institution

University of Wisconsin-Madison

EducationMadison, Wisconsin, United States
About: University of Wisconsin-Madison is a education organization based out in Madison, Wisconsin, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 108707 authors who have published 237594 publications receiving 11883575 citations.
Topics: Population, Poison control, Gene, Health care, Galaxy


Papers
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Journal ArticleDOI
TL;DR: This article introduces actuaries to the concept of “copulas,” a tool for understanding relationships among multivariate outcomes, a function that links univariate marginals to their full multivariate distribution, and several families of copulas that have appeared in the literature.
Abstract: This article introduces actuaries to the concept of “copulas,” a tool for understanding relationships among multivariate outcomes. A copula is a function that links univariate marginals to their full multivariate distribution. Copulas were introduced in 1959 in the context of probabilistic metric spaces. The literature on the statistical properties and applications of copulas has been developing rapidly in recent years. This article explores some of these practical applications, including estimation of joint life mortality and multidecrement models. In addition, we describe basic properties of copulas, their relationships to measures of dependence, and several families of copulas that have appeared in the literature. An annotated bibliography provides a resource for researchers and practitioners who wish to continue their study of copulas. For those who wish to use copulas for statistical inference, we illustrate statistical inference procedures by using insurance company data on losses and expen...

1,240 citations

Journal ArticleDOI
TL;DR: In this paper, the authors proposed a hypothetical valuation (HV) approach to elicit willingness to pay for or willingness to accept compensation for a recreational or other extramarket good (or bad).
Abstract: The well known travel cost method (TC)has been widely applied to outdoor recreation. A second approach has been referred to in the past as the Davis method, the questionnaire approach, and contingent valuation. It will here be termed hypothetical valuation (HV), since it involves creating a hypothetical situation designed to elicit willingness to pay for or willingness to accept compensation for a recreational or other extramarket good (or bad). TC and HV are termed "indirect methods", since they do not depend on the direct information about prices and quantities that economists would prefer to use where available to value goods and services.

1,240 citations

Journal ArticleDOI
TL;DR: Five processes that are essential for adaptive anticipatory responses to future threat uncertainty are identified and it is proposed that alterations in the neural instantiation of these processes result in maladaptive responses to uncertainty in pathological anxiety.
Abstract: Uncertainty about a possible future threat disrupts our ability to avoid it or to mitigate its negative impact and thus results in anxiety. Here, we focus the broad literature on the neurobiology of anxiety through the lens of uncertainty. We identify five processes that are essential for adaptive anticipatory responses to future threat uncertainty and propose that alterations in the neural instantiation of these processes result in maladaptive responses to uncertainty in pathological anxiety. This framework has the potential to advance the classification, diagnosis and treatment of clinical anxiety.

1,238 citations

Journal ArticleDOI
TL;DR: Since the guidelines were first issued back in 1980, Americans have gotten slightly healthier, except for children, got significantly bigger, gotten significantly bigger (especially children), and gotten very, very confused about what they should be eating.

1,238 citations

Journal ArticleDOI
TL;DR: All maize arose from a single domestication in southern Mexico about 9,000 years ago, consistent with a model based on the archaeological record suggesting that maize diversified in the highlands of Mexico before spreading to the lowlands.
Abstract: There exists extraordinary morphological and genetic diversity among the maize landraces that have been developed by pre-Columbian cultivators. To explain this high level of diversity in maize, several authors have proposed that maize landraces were the products of multiple independent domestications from their wild relative (teosinte). We present phylogenetic analyses based on 264 individual plants, each genotyped at 99 microsatellites, that challenge the multiple-origins hypothesis. Instead, our results indicate that all maize arose from a single domestication in southern Mexico about 9,000 years ago. Our analyses also indicate that the oldest surviving maize types are those of the Mexican highlands with maize spreading from this region over the Americas along two major paths. Our phylogenetic work is consistent with a model based on the archaeological record suggesting that maize diversified in the highlands of Mexico before spreading to the lowlands. We also found only modest evidence for postdomestication gene flow from teosinte into maize.

1,237 citations


Authors

Showing all 109671 results

NameH-indexPapersCitations
Eric S. Lander301826525976
Ronald C. Kessler2741332328983
Gordon H. Guyatt2311620228631
Yi Chen2174342293080
David Miller2032573204840
Robert M. Califf1961561167961
Ronald Klein1941305149140
Joan Massagué189408149951
Jens K. Nørskov184706146151
Terrie E. Moffitt182594150609
H. S. Chen1792401178529
Ramachandran S. Vasan1721100138108
Masayuki Yamamoto1711576123028
Avshalom Caspi170524113583
Jiawei Han1681233143427
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023333
20221,390
202110,148
20209,483
20199,278
20188,546