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Institution

University of Wisconsin-Madison

EducationMadison, Wisconsin, United States
About: University of Wisconsin-Madison is a education organization based out in Madison, Wisconsin, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 108707 authors who have published 237594 publications receiving 11883575 citations.
Topics: Population, Poison control, Gene, Health care, Galaxy


Papers
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Journal ArticleDOI
TL;DR: A simple method based on a linear log-log protein standard curve is presented to permit rapid and totally objective protein analysis using small programmable calculators.

8,197 citations

Journal ArticleDOI
TL;DR: This review focuses on model predictive control of constrained systems, both linear and nonlinear, and distill from an extensive literature essential principles that ensure stability to present a concise characterization of most of the model predictive controllers that have been proposed in the literature.

8,064 citations

Journal ArticleDOI
TL;DR: In this paper, the authors define the disturbance term as the sum of symmetric normal and (negative) half-normal random variables, and consider various aspects of maximum-likelihood estimation for the coefficients of a production function with an additive disturbance term of this sort.

8,058 citations

Journal ArticleDOI
05 Sep 1997-Science
TL;DR: The 4,639,221-base pair sequence of Escherichia coli K-12 is presented and reveals ubiquitous as well as narrowly distributed gene families; many families of similar genes within E. coli are also evident.
Abstract: The 4,639,221-base pair sequence of Escherichia coli K-12 is presented. Of 4288 protein-coding genes annotated, 38 percent have no attributed function. Comparison with five other sequenced microbes reveals ubiquitous as well as narrowly distributed gene families; many families of similar genes within E. coli are also evident. The largest family of paralogous proteins contains 80 ABC transporters. The genome as a whole is strikingly organized with respect to the local direction of replication; guanines, oligonucleotides possibly related to replication and recombination, and most genes are so oriented. The genome also contains insertion sequence (IS) elements, phage remnants, and many other patches of unusual composition indicating genome plasticity through horizontal transfer.

7,723 citations

Journal ArticleDOI
TL;DR: In this paper, a method of estimating the parameters of a set of regression equations is reported which involves application of Aitken's generalized least-squares to the whole system of equations.
Abstract: In this paper a method of estimating the parameters of a set of regression equations is reported which involves application of Aitken's generalized least-squares [1] to the whole system of equations. Under conditions generally encountered in practice, it is found that the regression coefficient estimators so obtained are at least asymptotically more efficient than those obtained by an equation-by-equation application of least squares. This gain in efficiency can be quite large if “independent” variables in different equations are not highly correlated and if disturbance terms in different equations are highly correlated. Further, tests of the hypothesis that all regression equation coefficient vectors are equal, based on “micro” and “macro” data, are described. If this hypothesis is accepted, there will be no aggregation bias. Finally, the estimation procedure and the “micro-test” for aggregation bias are applied in the analysis of annual investment data, 1935–1954, for two firms.

7,637 citations


Authors

Showing all 109671 results

NameH-indexPapersCitations
Eric S. Lander301826525976
Ronald C. Kessler2741332328983
Gordon H. Guyatt2311620228631
Yi Chen2174342293080
David Miller2032573204840
Robert M. Califf1961561167961
Ronald Klein1941305149140
Joan Massagué189408149951
Jens K. Nørskov184706146151
Terrie E. Moffitt182594150609
H. S. Chen1792401178529
Ramachandran S. Vasan1721100138108
Masayuki Yamamoto1711576123028
Avshalom Caspi170524113583
Jiawei Han1681233143427
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023333
20221,390
202110,148
20209,483
20199,278
20188,546