Institution
University of Wisconsin–Milwaukee
Education•Milwaukee, Wisconsin, United States•
About: University of Wisconsin–Milwaukee is a education organization based out in Milwaukee, Wisconsin, United States. It is known for research contribution in the topics: Population & Gravitational wave. The organization has 11839 authors who have published 28034 publications receiving 936438 citations. The organization is also known as: UWM & University of Wisconsin-Milwaukee.
Topics: Population, Gravitational wave, Poison control, LIGO, Health care
Papers published on a yearly basis
Papers
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University of North Carolina at Chapel Hill1, University of Michigan2, Renaissance Computing Institute3, University of Washington4, Broad Institute5, University of Wisconsin–Milwaukee6, Harvard University7, University of Oxford8, Norwegian University of Science and Technology9, Icahn School of Medicine at Mount Sinai10, University of Vermont11, Fred Hutchinson Cancer Research Center12, Erasmus University Rotterdam13, University of Mississippi14, University of Iceland15, University of Minnesota16, Washington University in St. Louis17, University of Edinburgh18, University of Texas Health Science Center at Houston19, University of Pittsburgh20, George Washington University21, University of Iowa22, Stanford University23, University of Auckland24, Ohio State University25, Boston University26, University of California, Los Angeles27, Jackson State University28, University of Copenhagen29, Technische Universität München30, Baylor College of Medicine31, Johns Hopkins University32, Group Health Cooperative33, University of Virginia34
TL;DR: This large whole-exome-sequencing study for LDL-C identified a gene not known to be implicated in LDL- C and provides unique insight into the design and analysis of similar experiments.
Abstract: Elevated low-density lipoprotein cholesterol (LDL-C) is a treatable, heritable risk factor for cardiovascular disease. Genome-wide association studies (GWASs) have identified 157 variants associated with lipid levels but are not well suited to assess the impact of rare and low-frequency variants. To determine whether rare or low-frequency coding variants are associated with LDL-C, we exome sequenced 2,005 individuals, including 554 individuals selected for extreme LDL-C (>98(th) or <2(nd) percentile). Follow-up analyses included sequencing of 1,302 additional individuals and genotype-based analysis of 52,221 individuals. We observed significant evidence of association between LDL-C and the burden of rare or low-frequency variants in PNPLA5, encoding a phospholipase-domain-containing protein, and both known and previously unidentified variants in PCSK9, LDLR and APOB, three known lipid-related genes. The effect sizes for the burden of rare variants for each associated gene were substantially higher than those observed for individual SNPs identified from GWASs. We replicated the PNPLA5 signal in an independent large-scale sequencing study of 2,084 individuals. In conclusion, this large whole-exome-sequencing study for LDL-C identified a gene not known to be implicated in LDL-C and provides unique insight into the design and analysis of similar experiments.
201 citations
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TL;DR: In this paper, the authors performed high-resolution magnetohydrodynamics simulations of binary neutron star mergers in numerical relativity on the Japanese supercomputer K. It is shown that a hypermassive neutron star (HMNS) formed after the merger is then subject to the nonaxisymmetric magnetorotational instability, which amplifies the magnetic field in the HMNS.
Abstract: We perform high-resolution magnetohydrodynamics simulations of binary neutron star mergers in numerical relativity on the Japanese supercomputer K. The neutron stars and merger remnants are covered by a grid spacing of 70 m, which yields the highest-resolution results among those derived so far. By an in-depth resolution study, we clarify several amplification mechanisms of magnetic fields during the binary neutron star merger for the first time. First, the Kelvin-Helmholtz instability developed in the shear layer at the onset of the merger significantly amplifies the magnetic fields. A hypermassive neutron star (HMNS) formed after the merger is then subject to the nonaxisymmetric magnetorotational instability, which amplifies the magnetic field in the HMNS. These two amplification mechanisms cannot be found with insufficient-resolution runs. We also show that the HMNS eventually collapses to a black hole surrounded by an accretion torus which is strongly magnetized at birth.
201 citations
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TL;DR: Research is reviewed on the impact of several contextual factors on tic expression and implications for future research and treatment development are discussed.
201 citations
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TL;DR: In this paper, the authors examined four explanations of corruption in American states: historical/cultural, political, structural, and bureaucratic, and found that corruption is associated with historical/culture, political forces, and government size and policies that increase bribe opportunities.
Abstract: This study is an empirical examination of political corruption in the American states. Using the number of public officials who are convicted of crimes involving corruption as the dependent variable, four explanations of corruption are examined--historical/cultural, political, structural, and bureaucratic. We find that corruption is associated with historical/cultural forces, political forces (especially turnout and party competition), and bureaucratic forces (government size and policies that increase bribe opportunities). Structural factors (e.g., campaign finance reporting requirements, centralization, direct democracy) are unrelated to the incidence of corruption. Finally, the study shows some evidence that prosecution of corrupt public officials was subject to partisan and racial targeting during the Reagan administration and racial targeting during the Carter administration.
201 citations
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TL;DR: It is found that, to get good agreement between theory and recent experimental measurements of H(c2), this helical structure is required, and a Josephson junction experiment is proposed that can be used to detect thishelical order.
Abstract: We consider the role of magnetic fields on the broken inversion superconductor CePt3Si. We show that the upper critical field for a field along the c axis exhibits a much weaker paramagnetic effect than for a field applied perpendicular to the c axis. The in-plane paramagnetic effect is strongly reduced by the appearance of helical structure in the order parameter. We find that, to get good agreement between theory and recent experimental measurements of H(c2), this helical structure is required. We propose a Josephson junction experiment that can be used to detect this helical order. In particular, we predict that the Josephson current will exhibit a magnetic interference pattern for a magnetic field applied perpendicular to the junction normal. We also discuss unusual magnetic effects associated with the helical order.
201 citations
Authors
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Name | H-index | Papers | Citations |
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Caroline S. Fox | 155 | 599 | 138951 |
Mark D. Griffiths | 124 | 1238 | 61335 |
Benjamin William Allen | 124 | 807 | 87750 |
James A. Dumesic | 118 | 615 | 58935 |
Richard O'Shaughnessy | 114 | 462 | 77439 |
Patrick Brady | 110 | 442 | 73418 |
Laura Cadonati | 109 | 450 | 73356 |
Stephen Fairhurst | 109 | 426 | 71657 |
Benno Willke | 109 | 508 | 74673 |
Benjamin J. Owen | 108 | 351 | 70678 |
Kenneth H. Nealson | 108 | 483 | 51100 |
P. Ajith | 107 | 372 | 70245 |
Duncan A. Brown | 107 | 567 | 68823 |
I. A. Bilenko | 105 | 393 | 68801 |
F. Fidecaro | 105 | 569 | 74781 |