University of Wisconsin–Milwaukee

About: University of Wisconsin–Milwaukee is a education organization based out in Milwaukee, Wisconsin, United States. It is known for research contribution in the topics: Population & Gravitational wave. The organization has 11839 authors who have published 28034 publications receiving 936438 citations. The organization is also known as: UWM & University of Wisconsin-Milwaukee.

Dynamics of Consumption and Food Conversion by Lake Michigan Alewives: An Energetics-Modeling Synthesis

Abstract: We developed an energetics model for the alewife Alosa pseudoharengus to evaluate consumption and conversion efficiency processes. We estimated alewife standard metabolism (R) as a function of wet body weight (W, g) and water temperature (T, °C): R (g˙g−1˙d−1) = 0.0073 W−0.215e0.0548T. We estimated maximum daily ration for 15-g, yearling alewives at 20°C to be as much as 37% of their body weight in experiments of 24 h. Modeling simulations based on observed growth in Lake Michigan indicated that yearling alewives may attain close to 70% of their estimated maximum consumption rate during September and October. Simulation results indicated wide seasonal variations in consumption rates; almost 50% of the yearly consumption by an individual adult alewife (age ≥ II) occurs in September and October, suggesting abundant food and possibly relaxed competition during that season. In contrast, adult alewives lose weight during the summer when stratification of Lake Michigan would permit orientation to water...

Stability of the money demand function in Asian developing countries

Abstract: Previous studies that estimated the money demand function in Asian developing countries either employed traditional estimation techniques or recently popularized cointegration technique. While the first group suffers from ‘spurious regression’ problems, the second group interpreted their finding of cointegration as a sign of stability of estimated parameters. This study, after incorporating the CUSUM and CUSUMSQ tests into cointegration analysis, shows that in some Asian countries even though real M1 or M2 monetary aggregates are cointegrated with their determinants, the estimated parameters are unstable.

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

Abstract: Most genome-wide association and fine-mapping studies to date have been conducted in individuals of European descent, and genetic studies of populations of Hispanic/Latino and African ancestry are limited. In addition, these populations have more complex linkage disequilibrium structure. In order to better define the genetic architecture of these understudied populations, we leveraged >100,000 phased sequences available from deep-coverage whole genome sequencing through the multi-ethnic NHLBI Trans-Omics for Precision Medicine (TOPMed) program to impute genotypes into admixed African and Hispanic/Latino samples with genome-wide genotyping array data. We demonstrated that using TOPMed sequencing data as the imputation reference panel improves genotype imputation quality in these populations, which subsequently enhanced gene-mapping power for complex traits. For rare variants with minor allele frequency (MAF) 86%. Subsequent association analyses of TOPMed reference panel-imputed genotype data with hematological traits (hemoglobin (HGB), hematocrit (HCT), and white blood cell count (WBC)) in ~21,600 African-ancestry and ~21,700 Hispanic/Latino individuals identified associations with two rare variants in the HBB gene (rs33930165 with higher WBC [p = 8.8x10-15] in African populations, rs11549407 with lower HGB [p = 1.5x10-12] and HCT [p = 8.8x10-10] in Hispanics/Latinos). By comparison, neither variant would have been genome-wide significant if either 1000 Genomes Project Phase 3 or Haplotype Reference Consortium reference panels had been used for imputation. Our findings highlight the utility of the TOPMed imputation reference panel for identification of novel rare variant associations not previously detected in similarly sized genome-wide studies of under-represented African and Hispanic/Latino populations.

Big Sky or Big Sprawl? Rural Gentrification and the Changing Cultural Landscape of Missoula, Montana

Abstract: The Rocky Mountain region has experienced significant growth in the last decade, caused mainly by in-migration of population. This paper explores the case of Missoula to examine the nature of this growth and its impacts upon the cultural landscape of the Big Sky country of Montana. Impacts from growth include increasing urbanization and sprawl, changing housing tastes, conspicuous consumption of open space, and spiraling real estate prices. The paper contends that such changes are caused by the in-migration of the new middle class in search of a Rocky Mountain lifestyle, creating a process of rural gentrification in which long-term residents are increasingly displaced. Vociferous public responses to these changes have created demands for affordable housing, control of sprawl, and protection of open space, leading to the implementation of new policies and regulatory measures in a state that is famous for its history of fierce, rugged individualism and an anti-regulatory culture.