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Institution

University of Wisconsin–Milwaukee

EducationMilwaukee, Wisconsin, United States
About: University of Wisconsin–Milwaukee is a education organization based out in Milwaukee, Wisconsin, United States. It is known for research contribution in the topics: Population & Gravitational wave. The organization has 11839 authors who have published 28034 publications receiving 936438 citations. The organization is also known as: UWM & University of Wisconsin-Milwaukee.


Papers
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Proceedings ArticleDOI
28 Jun 2000
TL;DR: In this paper, the presliding displacement and stiction properties of friction models are investigated, and a class of general one-state models is derived that is stable, dissipative and exhibits both stiction and pres liding displacement.
Abstract: The presliding displacement and stiction properties of friction models are investigated. It is found that existing single-state-variable friction models possess either stiction or presliding displacement. Next, those models with continuous states are interpreted as examples of Prandlt's elasto-plastic material model. A class of general one-state models is derived that is stable, dissipative and exhibits both stiction and presliding displacement.

180 citations

Journal ArticleDOI
TL;DR: In this article, case studies of three urban elementary schools were conducted to document the integration of technology given identical resources from a local university's PT3 grant, identifying three scaffolds that appear to have a significant influence on integration: alignment with the curriculum/mission, teacher leadership, and public/private roles for technology recognition.
Abstract: Case studies of three urban elementary schools were conducted to document the integration of technology given identical resources from a local university’s PT3 grant. Data sources for this qualitative study included participant observers’ field notes and journal entries, school personnel interviews, timeline and chronicle of technology-related priorities and events, and children’s and teachers’ technology artifacts. Cases were summarized with respect to prior technology context, agents of growth and development, and changes and future directions. The analysis identified three scaffolds that appear to have a significant influence on—and redefine the challenge of—technology integration: alignment with the curriculum/mission, teacher leadership, and public/private roles for technology recognition.

180 citations

Journal ArticleDOI
TL;DR: The present study tests the roles of classical estrogen receptors (ERα and ERβ) and mGluR1a in mediating the effects of E2 on hippocampal memory consolidation, and provides the first in vivo evidence demonstrating that ER/mGLUR signaling can mediate the beneficial effects ofE2 on hippocampusalMemory consolidation.
Abstract: Our laboratory has demonstrated that 17β-estradiol (E2) enhances hippocampal memory consolidation via rapid activation of multiple intracellular signaling cascades, including the ERK/MAPK cascade (Fernandez et al., 2008; Fan et al., 2010). However, the receptor mechanisms responsible for these effects of E2 remain unclear. In vitro, estrogen receptor α (ERα) signaling through metabotropic glutamate receptor 1a (mGluR1a) leads to ERK-dependent CREB phosphorylation (Boulware et al., 2005), suggesting that interactions between ERs and mGluR1a may be vital to the memory-enhancing effects of E2. As such, the present study tested the roles of classical estrogen receptors (ERα and ERβ) and mGluR1a in mediating the effects of E2 on hippocampal memory consolidation. Dorsal hippocampal (DH) infusion of ERα (PPT) or ERβ (DPN) agonists enhanced novel object recognition and object placement memory in ovariectomized female mice in an ERK-dependent manner, suggesting that these receptors influence memory by rapidly activating hippocampal cell signaling. Next, DH infusion of the mGluR1a antagonist LY367385 blocked the object and spatial memory facilitation induced by E2, PPT, and DPN, demonstrating that ER/mGluR1a signaling is critical for the memory-enhancing effects of E2. Finally, we show that ERα, ERβ, mGluR1, and ERK all reside within specialized membrane microdomains of the DH, and that ERα and ERβ physically interact with mGluR1, providing a means through which ERs may activate mGluRs and downstream signaling. Together, these findings provide the first in vivo evidence demonstrating that ER/mGluR signaling can mediate the beneficial effects of E2 on hippocampal memory consolidation.

180 citations

Journal ArticleDOI
TL;DR: It appears RAS biofilters harbor complex microbial communities whose composition can be affected directly by typical system operations while supporting multiple ammonia oxidation lifestyles within the nitrifying consortium.
Abstract: Recirculating aquaculture systems (RAS) are unique engineered ecosystems that minimize environmental perturbation by reducing nutrient pollution discharge. RAS typically employ a biofilter to control ammonia levels produced as a byproduct of fish protein catabolism. Nitrosomonas (ammonia-oxidizing), Nitrospira and Nitrobacter (nitrite-oxidizing) species are thought to be the primary nitrifiers present in RAS biofilters. We explored this assertion by characterizing the biofilter bacterial and archaeal community of a commercial scale freshwater RAS that has been in operation for >15 years. We found the biofilter community harbored a diverse array of bacterial taxa (>1000 genus-level taxon assignments) dominated by Chitinophagaceae (~12%) and Acidobacteria (~9%). The bacterial community exhibited significant composition shifts with changes in biofilter depth and in conjunction with operational changes across a fish rearing cycle. Archaea also were abundant, and were comprised solely of a low diversity assemblage of Thaumarchaeota (>95%), thought to be ammonia-oxidizing archaea (AOA) from the presence of AOA ammonia monooxygenase genes. Nitrosomonas were present at all depths and time points. However, their abundance was >3 orders of magnitude less than AOA and exhibited significant depth-time variability not observed for AOA. Phylogenetic analysis of the nitrite oxidoreductase beta subunit (nxrB) gene indicated two distinct Nitrospira populations were present, while Nitrobacter were not detected. Subsequent identification of Nitrospira ammonia monooxygenase alpha subunit genes in conjunction with the phylogenetic placement and quantification of the nxrB genotypes suggests complete ammonia-oxidizing (comammox) and nitrite-oxidizing Nitrospira populations co-exist with relatively equivalent and stable abundances in this system. It appears RAS biofilters harbor complex microbial communities whose composition can be affected directly by typical system operations while supporting multiple ammonia oxidation lifestyles within the nitrifying consortium.

180 citations

Journal ArticleDOI
01 Mar 2005-Ecology
TL;DR: This is the first study to demonstrate that competition for pollination directly in- fluences outcrossing rates, and suggests that in self-compatible populations with genetic load, competition forpollination may not only reduce seed quantity, but may also lower seed quality.
Abstract: Sympatric plant species with similar flowering phenologies and floral mor- phologies may compete for pollination, and as a consequence potentially influence each other's reproductive success and mating system. Two likely competitors are Mimulus ringens and Lobelia siphilitica, which co-occur in wet meadows of central and eastern North Amer- ica, produce blue zygomorphic flowers, and share several species of bumble bee pollinators. To test for effects of competition for pollination, we planted experimental arrays of Mimulus ringens, each consisting of genets with unique combinations of homozygous marker ge- notypes. In two arrays we planted mixtures of Mimulus and Lobelia, and in two additional arrays we planted Mimulus without a competitor for pollination. Bumble bee pollinators frequently moved between Mimulus and Lobelia flowers in the mixed-species arrays, with 42% of plant-to-plant movements being interspecific transitions. Pollinator movements between species were associated with a reduction in the amount of conspecific pollen arriving on Mimulus stigmas. The presence of Lobelia led to a significant 37% reduction in the mean number of Mimulus seeds per fruit. In addition, Mimulus had a significantly lower rate of outcrossing in the mixed-species arrays (0.43) than in the ''pure'' arrays (0.63). This is the first study to demonstrate that competition for pollination directly in- fluences outcrossing rates. Our work suggests that in self-compatible populations with genetic load, competition for pollination may not only reduce seed quantity, but may also lower seed quality.

180 citations


Authors

Showing all 11948 results

NameH-indexPapersCitations
Caroline S. Fox155599138951
Mark D. Griffiths124123861335
Benjamin William Allen12480787750
James A. Dumesic11861558935
Richard O'Shaughnessy11446277439
Patrick Brady11044273418
Laura Cadonati10945073356
Stephen Fairhurst10942671657
Benno Willke10950874673
Benjamin J. Owen10835170678
Kenneth H. Nealson10848351100
P. Ajith10737270245
Duncan A. Brown10756768823
I. A. Bilenko10539368801
F. Fidecaro10556974781
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202330
2022194
20211,150
20201,189
20191,085
20181,141