Institution
University of Wisconsin–Milwaukee
Education•Milwaukee, Wisconsin, United States•
About: University of Wisconsin–Milwaukee is a education organization based out in Milwaukee, Wisconsin, United States. It is known for research contribution in the topics: Population & Gravitational wave. The organization has 11839 authors who have published 28034 publications receiving 936438 citations. The organization is also known as: UWM & University of Wisconsin-Milwaukee.
Topics: Population, Gravitational wave, Poison control, LIGO, Health care
Papers published on a yearly basis
Papers
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TL;DR: In this paper, a host-guest chemistry strategy was proposed to construct Fe-mIm nanocluster (NC) (guest)@zeolite imidazole framework-8 (ZIF-8) precursors that can be transformed into Fe-N/C electrocatalysts with controllable structures.
Abstract: Even though Fe-N/C electrocatalysts with abundant Fe-Nx active sites have been developed as one of the most promising alternatives to precious metal materials for oxygen reduction reaction (ORR), further improvement of their performance requires precise control over Fe-Nx sites at the molecular level and deep understanding of the catalytic mechanism associated with each particular structure. Herein, we report a host–guest chemistry strategy to construct Fe-mIm nanocluster (NC) (guest)@zeolite imidazole framework-8 (ZIF-8) (host) precursors that can be transformed into Fe-N/C electrocatalysts with controllable structures. The ZIF-8 host network exhibits a significant host–guest relationship dependent confinement effect for the Fe-mIm NCs during the pyrolysis process, resulting in different types of Fe-Nx sites with two- to five-coordinated configurations on the porous carbon matrix confirmed by X-ray absorption near edge structure (XANES) and Fourier transform (FT) extended X-ray absorption fine structure ...
436 citations
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Goddard Space Flight Center1, West Virginia University2, Cornell University3, Pennsylvania State University4, Notre Dame of Maryland University5, Montana State University6, Franklin & Marshall College7, University of Virginia8, University of British Columbia9, Lafayette College10, National Radio Astronomy Observatory11, Hillsdale College12, Norwich University13, California Institute of Technology14, McGill University15, University of Illinois at Urbana–Champaign16, University of Washington17, University of Wisconsin–Milwaukee18, Columbia University19, Haverford College20, The University of Texas Rio Grande Valley21, First Green Bank22, United States Naval Research Laboratory23, Eötvös Loránd University24, Oberlin College25, Chinese Academy of Sciences26
TL;DR: In this paper, an isotropic stochastic GWB in the newly released 11-year data set from the North American Nanohertz Observatory for Gravitational Waves (NANOGrav) was searched for and the first pulsar-timing array (PTA) constraints that are robust against SSE errors were obtained.
Abstract: We search for an isotropic stochastic gravitational-wave background (GWB) in the newly released 11 year data set from the North American Nanohertz Observatory for Gravitational Waves (NANOGrav). While we find no evidence for a GWB, we place constraints on a population of inspiraling supermassive black hole (SMBH) binaries, a network of decaying cosmic strings, and a primordial GWB. For the first time, we find that the GWB constraints are sensitive to the solar system ephemeris (SSE) model used and that SSE errors can mimic a GWB signal. We developed an approach that bridges systematic SSE differences, producing the first pulsar-timing array (PTA) constraints that are robust against SSE errors. We thus place a 95% upper limit on the GW-strain amplitude of A_(GWB) < 1.45 × 10^(−15) at a frequency of f = 1 yr^(−1) for a fiducial f^(−2/3) power-law spectrum and with interpulsar correlations modeled. This is a factor of ~2 improvement over the NANOGrav nine-year limit calculated using the same procedure. Previous PTA upper limits on the GWB (as well as their astrophysical and cosmological interpretations) will need revision in light of SSE systematic errors. We use our constraints to characterize the combined influence on the GWB of the stellar mass density in galactic cores, the eccentricity of SMBH binaries, and SMBH–galactic-bulge scaling relationships. We constrain the cosmic-string tension using recent simulations, yielding an SSE-marginalized 95% upper limit of Gμ < 5.3 × 10^(−11)—a factor of ~2 better than the published NANOGrav nine-year constraints. Our SSE-marginalized 95% upper limit on the energy density of a primordial GWB (for a radiation-dominated post-inflation universe) is Ω_(GWB)(f) h^2 < 3.4 × 10^(−10).
436 citations
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University of Colorado Boulder1, Pacific Northwest National Laboratory2, United States Department of Energy3, University of Saskatchewan4, Helmholtz Centre for Environmental Research - UFZ5, University of Illinois at Urbana–Champaign6, University of California, Merced7, Flinders University8, Institut national de la recherche agronomique9, University of Aberdeen10, Spanish National Research Council11, Bangor University12, University of Vienna13, HAMK University of Applied Sciences14, University of Wisconsin–Milwaukee15, Swiss Federal Institute of Aquatic Science and Technology16, University of Sydney17, University of Münster18, University of Eastern Finland19, Dresden University of Technology20, University of Girona21, Commonwealth Scientific and Industrial Research Organisation22, University of Texas at Tyler23, University of Montana24, College of William & Mary25, North Dakota State University26, University of Porto27, Southern California Coastal Water Research Project28, Swedish University of Agricultural Sciences29, Virginia Tech30, Yonsei University31, University of Tokyo32, University of Cádiz33, Uppsala University34, Laurentian University35, Duke University36
TL;DR: In this article, a statistical analysis investigating the value of environmental data and microbial community structure independently and in combination for explaining rates of carbon and nitrogen cycling processes within 82 global datasets is presented.
Abstract: Microorganisms are vital in mediating the earth's biogeochemical cycles; yet, despite our rapidly increasing ability to explore complex environmental microbial communities, the relationship between microbial community structure and ecosystem processes remains poorly understood. Here, we address a fundamental and unanswered question in microbial ecology: 'When do we need to understand microbial community structure to accurately predict function?' We present a statistical analysis investigating the value of environmental data and microbial community structure independently and in combination for explaining rates of carbon and nitrogen cycling processes within 82 global datasets. Environmental variables were the strongest predictors of process rates but left 44% of variation unexplained on average, suggesting the potential for microbial data to increase model accuracy. Although only 29% of our datasets were significantly improved by adding information on microbial community structure, we observed improvement in models of processes mediated by narrow phylogenetic guilds via functional gene data, and conversely, improvement in models of facultative microbial processes via community diversity metrics. Our results also suggest that microbial diversity can strengthen predictions of respiration rates beyond microbial biomass parameters, as 53% of models were improved by incorporating both sets of predictors compared to 35% by microbial biomass alone. Our analysis represents the first comprehensive analysis of research examining links between microbial community structure and ecosystem function. Taken together, our results indicate that a greater understanding of microbial communities informed by ecological principles may enhance our ability to predict ecosystem process rates relative to assessments based on environmental variables and microbial physiology.
436 citations
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TL;DR: A new device for measuring in vivo fluorescence over time, allowing minimally invasive assessment of construct expression in the intact brain and a set of optogenetic tools designed for optogenetics experiments in the non-human primate brain are presented.
Abstract: Optogenetics is a technique for controlling subpopulations of neurons in the intact brain using light. This technique has the potential to enhance basic systems neuroscience research and to inform the mechanisms and treatment of brain injury and disease. Before launching large-scale primate studies, the method needs to be further characterized and adapted for use in the primate brain. We assessed the safety and efficiency of two viral vector systems (lentivirus and adeno-associated virus), two human promoters (human synapsin (hSyn) and human thymocyte-1 (hThy-1)) and three excitatory and inhibitory mammalian codon-optimized opsins (channelrhodopsin-2, enhanced Natronomonas pharaonis halorhodopsin and the step-function opsin), which we characterized electrophysiologically, histologically and behaviorally in rhesus monkeys (Macaca mulatta). We also introduced a new device for measuring in vivo fluorescence over time, allowing minimally invasive assessment of construct expression in the intact brain. We present a set of optogenetic tools designed for optogenetic experiments in the non-human primate brain.
436 citations
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TL;DR: The genome project revealed the unique biochemistry of G. oxydans with respect to the process of incomplete oxidation and revealed many membrane-bound dehydrogenases that are critical for the incomplete oxidation of biotechnologically important substrates.
Abstract: Gluconobacter oxydans is unsurpassed by other organisms in its ability to incompletely oxidize a great variety of carbohydrates, alcohols and related compounds. Furthermore, the organism is used for several biotechnological processes, such as vitamin C production. To further our understanding of its overall metabolism, we sequenced the complete genome of G. oxydans 621H. The chromosome consists of 2,702,173 base pairs and contains 2,432 open reading frames. In addition, five plasmids were identified that comprised 232 open reading frames. The sequence data can be used for metabolic reconstruction of the pathways leading to industrially important products derived from sugars and alcohols. Although the respiratory chain of G. oxydans was found to be rather simple, the organism contains many membrane-bound dehydrogenases that are critical for the incomplete oxidation of biotechnologically important substrates. Moreover, the genome project revealed the unique biochemistry of G. oxydans with respect to the process of incomplete oxidation.
435 citations
Authors
Showing all 11948 results
Name | H-index | Papers | Citations |
---|---|---|---|
Caroline S. Fox | 155 | 599 | 138951 |
Mark D. Griffiths | 124 | 1238 | 61335 |
Benjamin William Allen | 124 | 807 | 87750 |
James A. Dumesic | 118 | 615 | 58935 |
Richard O'Shaughnessy | 114 | 462 | 77439 |
Patrick Brady | 110 | 442 | 73418 |
Laura Cadonati | 109 | 450 | 73356 |
Stephen Fairhurst | 109 | 426 | 71657 |
Benno Willke | 109 | 508 | 74673 |
Benjamin J. Owen | 108 | 351 | 70678 |
Kenneth H. Nealson | 108 | 483 | 51100 |
P. Ajith | 107 | 372 | 70245 |
Duncan A. Brown | 107 | 567 | 68823 |
I. A. Bilenko | 105 | 393 | 68801 |
F. Fidecaro | 105 | 569 | 74781 |