Showing papers by "University of Wollongong published in 2006"

Health benefits of herbs and spices: the past, the present, the future

Abstract: UNLABELLED Herbs and spices have a traditional history of use, with strong roles in cultural heritage, and in the appreciation of food and its links to health. Demonstrating the benefits of foods by scientific means remains a challenge, particularly when compared with standards applied for assessing pharmaceutical agents. Pharmaceuticals are small-molecular-weight compounds consumed in a purified and concentrated form. Food is eaten in combinations, in relatively large, unmeasured quantities under highly socialised conditions. The real challenge lies not in proving whether foods, such as herbs and spices, have health benefits, but in defining what these benefits are and developing the methods to expose them by scientific means. CULTURAL ASPECTS The place of herbs and spices in the diet needs to be considered in reviewing health benefits. This includes definitions of the food category and the way in which benefits might be viewed, and therefore researched. Research may focus on identifying bioactive substances in herbs and spices, or on their properties as a whole food, and/or be set in the context of a dietary cuisine. THE ROLE OF HERBS AND SPICES IN HEALTH The antioxidant properties of herbs and spices are of particular interest in view of the impact of oxidative modification of low-density lipoprotein cholesterol in the development of atherosclerosis. There is level III-3 evidence (National Health and Medical Research Council [NHMRC] levels of evidence) that consuming a half to one clove of garlic (or equivalent) daily may have a cholesterol-lowering effect of up to 9%. There is level III-1 evidence that 7.2 g of aged garlic extract has been associated with anticlotting (in-vivo studies), as well as modest reductions in blood pressure (an approximate 5.5% decrease in systolic blood pressure). A range of bioactive compounds in herbs and spices have been studied for anticarcinogenic properties in animals, but the challenge lies in integrating this knowledge to ascertain whether any effects can be observed in humans, and within defined cuisines. Research on the effects of herbs and spices on mental health should distinguish between cognitive decline associated with ageing and the acute effects of psychological and cognitive function. There is level I and II evidence for the effect of some herbal supplements on psychological and cognitive function. There is very limited scientific evidence for the effects of herbs and spices on type 2 diabetes mellitus, with the best evidence being available for the effect of ginseng on glycaemia, albeit based on four studies. More research is required, particularly examining the effects of chronic consumption patterns. With increasing interest in alternatives to non-steroidal anti-inflammatory agents in the management of chronic inflammation, research is emerging on the use of food extracts. There is level II evidence for the use of ginger in ameliorating arthritic knee pain; however, the improvement is modest and the efficacy of ginger treatment is ranked below that of ibuprofen. More definitive research is required. PUBLIC HEALTH AND DIETARY IMPLICATIONS Recommendations for intakes of food in the Australian guide to healthy eating do not yet include suggested intakes of herbs and spices. Future consideration should be given to including more explicit recommendations about their place in a healthy diet. In addition to delivering antioxidant and other properties, herbs and spices can be used in recipes to partially or wholly replace less desirable ingredients such as salt, sugar and added saturated fat in, for example, marinades and dressings, stir-fry dishes, casseroles, soups, curries and Mediterranean-style cooking. Vegetable dishes and vegetarian options may be more appetising when prepared with herbs and spices. FUTURE DIRECTIONS As several metabolic diseases and age-related degenerative disorders are closely associated with oxidative processes in the body, the use of herbs and spices as a source of antioxidants to combat oxidation warrants further attention. Immediate studies should focus on validating the antioxidant capacity of herbs and spices after harvest, as well as testing their effects on markers of oxidation. This will work in parallel with clinical trials that are aiming to establish antioxidants as mediators of disease prevention. From a dietary perspective, the functionality of herbs and spices will be exposed through consideration of their properties as foods. As with most foods, the real benefits of including them in the diet are likely to emerge with a better understanding of the attributes of health that are best supported by food, and in methodological developments addressing the evidence base for their effects. These developments are well underway through evidence-based frameworks for substantiating health claims related to foods. At present, recommendations are warranted to support the consumption of foods rich in bioactive components, such as herbs and spices. With time, we can expect to see a greater body of scientific evidence supporting the benefits of herbs and spices in the overall maintenance of health and protection from disease.

Health benefits of herbs and spices: the past, the present, the future - Public Health

Abstract: Recommendations for intakes fo food in the Australian Guide to Healthy Eating do not yet include suggested intakes of herbs and spices, although several dietary guidelines refer to their benefits. Future consideration should be given to including more explicit recommendations about the place of herbs and spices in a healthy diet

Highly reversible lithium storage in spheroidal carbon-coated silicon nanocomposites as anodes for lithium-ion batteries.

Abstract: [*] S.-H. Ng, Dr. J. Wang, Dr. K. Konstantinov, Dr. Z.-P. Guo, Prof. H.-K. Liu Institute for Superconducting & Electronic Materials and ARC Centre of Excellence for Electromaterials Science University of Wollongong Wollongong, NSW 2522 (Australia) Fax: (+61)2-4221-5731 E-mail: hua_liu@uow.edu.au Homepage: http://www.uow.edu.au/eng/research/isem/staff/ hkliu.html Dr. D. Wexler Faculty of Engineering University of Wollongong Wollongong, NSW 2522 (Australia) [**] Financial support provided by the Australian Research Council (ARC) through the ARC Centre of Excellence funding (CE0561616) is gratefully acknowledged. Moreover, the authors are grateful to SauYen Chew at the University of Wollongong for experimental assistance. Finally, we also thank Dr. Tania Silver at the University of Wollongong for critical reading of the manuscript. Supporting information for this article is available on the WWW under http://www.angewandte.org or from the author. Communications

Targeting C-reactive protein for the treatment of cardiovascular disease

Abstract: Complement-mediated inflammation exacerbates the tissue injury of ischaemic necrosis in heart attacks and strokes, the most common causes of death in developed countries. Large infarct size increases immediate morbidity and mortality and, in survivors of the acute event, larger non-functional scars adversely affect long-term prognosis. There is thus an important unmet medical need for new cardioprotective and neuroprotective treatments. We have previously shown that human C-reactive protein (CRP), the classical acute-phase protein that binds to ligands exposed in damaged tissue and then activates complement1, increases myocardial and cerebral infarct size in rats subjected to coronary or cerebral artery ligation, respectively2, 3. Rat CRP does not activate rat complement, whereas human CRP activates both rat and human complement4. Administration of human CRP to rats is thus an excellent model for the actions of endogenous human CRP2, 3. Here we report the design, synthesis and efficacy of 1,6-bis(phosphocholine)-hexane as a specific small-molecule inhibitor of CRP. Five molecules of this palindromic compound are bound by two pentameric CRP molecules, crosslinking and occluding the ligand-binding B-face of CRP and blocking its functions. Administration of 1,6-bis(phosphocholine)-hexane to rats undergoing acute myocardial infarction abrogated the increase in infarct size and cardiac dysfunction produced by injection of human CRP. Therapeutic inhibition of CRP is thus a promising new approach to cardioprotection in acute myocardial infarction, and may also provide neuroprotection in stroke. Potential wider applications include other inflammatory, infective and tissue-damaging conditions characterized by increased CRP production, in which binding of CRP to exposed ligands in damaged cells may lead to complement-mediated exacerbation of tissue injury.

The feedback-regulated growth of black holes and bulges through gas accretion and starbursts in cluster central dominant galaxies

Abstract: We present an analysis of the growth of black holes through accretion and bulges through star formation in 33 galaxies at the centers of cooling flows. Most of these systems show evidence of cavities in the intracluster medium (ICM) inflated by radio jets emanating from their active galactic nuclei (AGNs). We present a new and extensive analysis of X-ray cavities in these systems. We find that AGNs are energetically able to balance radiative losses (cooling) from the ICM in more than half of our sample. We examine the relationship between cooling and star formation and find that the star formation rates are approaching or are comparable to X-ray and far-UV limits on the rates of gas condensation onto the central galaxy. The vast gulf between radiative losses and the sink of cooling material, which has been the primary objection to cooling flows, has narrowed significantly. Using the cavity (jet) powers, we place strong lower limits on the rate of growth of the central black holes, and we find that they are growing at an average rate of ~0.1 M? yr-1, with some systems growing as quickly as ~1 M? yr-1. We find a trend between bulge growth (star formation) and black hole growth that is approximately in accordance with the slope of the local (Magorrian) relation between black hole and bulge mass, but the scatter suggests that bulges and black holes do not necessarily grow in lockstep. Bondi accretion can power the low-luminosity sources, provided the nuclear gas density rises as ~r-1 to the Bondi radius, but is probably too feeble to fuel the most powerful outbursts.

Musculoskeletal disorders associated with obesity: a biomechanical perspective.

Abstract: Despite the multifactorial nature of musculoskeletal disease, obesity consistently emerges as a key and potentially modifiable risk factor in the onset and progression of musculoskeletal conditions of the hip, knee, ankle, foot and shoulder. To date, the majority of research has focused on the impact of obesity on bone and joint disorders, such as the risk of fracture and osteoarthritis. However, emerging evidence indicates that obesity may also have a profound effect on soft-tissue structures, such as tendon, fascia and cartilage. Although the mechanism remains unclear, the functional and structural limitations imposed by the additional loading of the locomotor system in obesity have been almost universally accepted to produce aberrant mechanics during locomotor tasks, thereby unduly raising stress within connective-tissue structures and the potential for musculoskeletal injury. While such mechanical theories abound, there is surprisingly little scientific evidence directly linking musculoskeletal injury to altered biomechanics in the obese. For the most part, even the biomechanical effects of obesity on the locomotor system remain unknown. Given the global increase in obesity and the rapid rise in musculoskeletal disorders, there is a need to determine the physical consequences of continued repetitive loading of major structures of the locomotor system in the obese and to establish how obesity may interact with other factors to potentially increase the risk of musculoskeletal disease.

Are You Selling the Right Colour? A Cross‐cultural Review of Colour as a Marketing Cue

Abstract: Should a marketer adopt a pan‐cultural or a culture‐specific approach when using colour in marketing? Colours exercise powerful effects and induce reactions based on both instincts and associations. Colours alter the meanings of the objects or situations with which they are associated and colour preferences can predict consumers' behaviour. This article reviews the psychological and socio‐cultural associations and meanings of colour(s) in a cross‐cultural marketing perspective and outlines their role as a marketing cue. Because cultural values, marketing objectives and desired customer relationship levels influence the choice of colour in corporate and marketing communications, it is argued that a cross‐cultural perspective of colour research and application is imperative for developing global marketing strategies.

An evaluation of SME development in Malaysia

Abstract: Small and medium enterprises (SMEs) in play a vital role in the Malaysian economy and are considered to be the backbone of industrial development in the country. However, few studies examined their development, challenges and future prospects. Therefore, the aim of this paper is to examine and analyse the role of SMEs in different sectors as well as their major contribution to the economy. The paper goes further to review the existing literature as well as the empirical studies in order to identify the major challenges (domestically and globally) that face this sector. The key messages from the studies examined in this paper are that Malaysian SMEs still face many domestic and global challenges in achieving economies of scale and competing internationally. Among the challenges are the low level of technological capabilities and limited skilled human capital resources, a low level of technology and ICT penetration, low levels of research and development (R&D), a substantial orientation towards domestic markets, a high level of international competition (for example, from China and India), a high level of bureaucracy in government agencies, and internal sourcing of funds. These characteristics suggest that government programs and incentives are either insufficient or not delivered effectively enough to overcome these problems. This paper attempts to identify the challenges as a positive first step towards formulating a workable framework for the SMEs to overcome them.

Using Acceptance and Commitment Training in the Support of Parents of Children Diagnosed with Autism

Abstract: Parents of autistic children face enormous challenges, but very little attention has been paid to their psychological needs. Acceptance and Commitment Therapy (ACT) has previously been tested with parents as part of a comprehensive package, but not yet alone. The present study used a within-subject, repeated measures design to test the effects of a 2-day (14 hour) group ACT workshop on 20 normal parents/guardians of children diagnosed with autism. Parents were assessed three weeks before the workshop, one week before, one week after, and three months after. No significant change occurred while waiting for treatment, but pre to post improvements were found on the Beck Depression Inventory-II (BDI-II), and the Global Severity Index (GSI) of the Brief Symptom Inventory (BSI). Significant pre to follow-up improvements were observed on the BDI-II, BSI, and the General Health Questionnaire-12. Processes measures of experiential avoidance and cognitive fusion also changed and there was some evidence tha...

Musculoskeletal disorders associated with obesity: a biomechanical perspective

Abstract: Despite the multifactorial nature of musculoskeletal disease, obesity consistently emerges as a key and potentially modifiable risk factor in the onset and progression of musculoskeletal conditions of the hip, knee, ankle, foot and shoulder. To date, the majority of research has focused on the impact of obesity on bone and joint disorders, such as the risk of fracture and osteoarthritis. However, emerging evidence indicates that obesity may also have a profound effect on soft-tissue structures, such as tendon, fascia and cartilage. Although the mechanism remains unclear, the functional and structural limitations imposed by the additional loading of the locomotor system in obesity have been almost universally accepted to produce aberrant mechanics during locomotor tasks, thereby unduly raising stress within connective-tissue structures and the potential for musculoskeletal injury. While such mechanical theories abound, there is surprisingly little scientific evidence directly linking musculoskeletal injury to altered biomechanics in the obese. For the most part, even the biomechanical effects of obesity on the locomotor system remain unknown. Given the global increase in obesity and the rapid rise in musculoskeletal disorders, there is a need to determine the physical consequences of continued repetitive loading of major structures of the locomotor system in the obese and to establish how obesity may interact with other factors to potentially increase the risk of musculoskeletal disease.

Cognitive-behavioral, solution-focused life coaching: Enhancing goal striving, well-being, and hope

Abstract: Research is in its infancy in the newly emerging field of coaching psychology. This study examined the effects of a 10-week cognitive-behavioral, solution-focused life coaching group programme. Participants were randomly allocated to a life coaching group programme (n = 28) or a waitlist control group (n = 28). Participation in the life coaching group programme was associated with significant increases in goal striving, well-being and hope, with gains maintained up to 30 weeks later on some variables. Hope theory may explain such positive outcomes. Life coaching programmes that utilize evidence-based techniques may provide a framework for further research on psychological processes that occur in non-clinical populations who wish to make purposeful change and enhance their positive psychological functioning.

Stages of recovery instrument: development of a measure of recovery from serious mental illness.

Abstract: Objective: In order to realize the vision of recovery-orientated mental health services, there is a need for a model and a method of measuring recovery as the concept is described by mental health consumers. A preliminary five-stage model based on consumer accounts was developed in an earlier study by the authors. This next stage of the research program describes the development and initial testing of a stage measure which, when validated, can be used in testing that model.Method: Existing measures of recovery were reviewed to assess their concordance with the model, and a new measure, the Stages of Recovery Instrument (STORI) was subsequently developed. A postal survey was conducted of 94 volunteers from the NISAD Schizophrenia Research Register. Participants completed the STORI and measures of mental health, psychological wellbeing, hope, resilience and recovery.Results: The STORI correlated with all of the psychological health variables, and the five stage subscales were found to be internally consiste...

Behavior of High Strength Structural Steel at Elevated Temperatures

Abstract: This paper presents the mechanical properties of high strength structural steel and mild structural steel at elevated temperatures Mechanical properties of structural steel at elevated temperatures are important for fire resistant design of steel structures However, current design standards for fire resistance of steel structures are mainly based on the investigation of hot-rolled carbon steel with normal strength, such as mild steel The performance of high strength steel at elevated temperatures is unknown Hence, an experimental program has been carried out to investigate the mechanical properties of both high strength steel and mild steel at elevated temperatures The high strength steel BISPLATE 80 (approximately equivalent to ASTM A 514, EN 10137-2 Grade S690Q, and JIS G 3128) and the mild steel XLERPLATE Grade 350 (approximately equivalent to ASTM 573-450) were tested using steady and transient-state test methods The elastic moduli and yield strengths were obtained at different strain levels, and the ultimate strength and thermal elongation were evaluated at different temperatures It is shown that the reduction factors of yield strength and elastic modulus of high strength steel and mild steel are quite similar for the temperature ranging from 22 to 540°C The test results were compared with the predictions obtained from the American, Australian, British, and European standards

Carbon‐Nanotube‐Reinforced Polyaniline Fibers for High‐Strength Artificial Muscles

Abstract: Actuating materials capable of producing useful movement and forces are recognized as the “missing link” in the development of a wide range of frontier technologies including haptic devices, microelectromechanical systems (MEMS), and even molecular machines. Immediate uses for these materials include an electronic Braille screen, a rehabilitation glove, tremor suppression, and a variable-camber propeller. Most of these applications could be realized with actuators that have equivalent performance to natural skeletal muscle. Although many actuator materials are available, none have the same mix of speed, movement, and force as skeletal muscle. Indeed, the actuator community was challenged to produce a material capable of beating a human in an arm wrestling match. This challenge remains to be met. One class of materials that has received considerable attention as actuators is low-voltage electrochemical systems utilizing conducting polymers and carbon nanotubes. Low-voltage sources are convenient and safe, and power inputs are potentially low. One deficiency of conducting polymers and nanotubes compared with skeletal muscle is their low actuation strains: less than 15 % for conducting polymers and less than 1 % for nanotubes. It has been argued that the low strains can be mechanically amplified (levers, bellows, hinges, etc.) to produce useful movements, but higher forces are needed to operate these amplifiers. In recent studies of the forces and displacements generated from conducting-polymer actuators, it has become obvious that force generation is limited by the breaking strength of the actuator material. Baughman has predicted that the maximum stress generated by an actuator can be estimated as 50 % of the breaking stress, so that for highly drawn polyaniline (PAni) fibers, stresses on the order of 190 MPa should be achievable. However, in practice the breaking stresses of conducting-polymer fibers when immersed in electrolyte and operated electromechanically are significantly lower than their dry-state strengths. The reasons for the loss of strength are not well known, but the limitations on actuator performance are severe. The highest reported stress that can be sustained by conducting polymers during actuator work cycles is in the range 20–34 MPa for polypyrrole (PPy) films. However, the maximum stress that can be sustained by PPy during actuation appears to be very sensitive to the dopant ion and polymerization conditions used, with many studies showing maximum stress values of less than 10 MPa. The low stress generation from conducting polymers, limited by the low breaking strengths, mean that the application of mechanical amplifiers is also very limited. To improve the mechanical performance, we have investigated the use of carbon nanotubes as reinforcing fibers in a polyaniline (PAni) matrix. Previous work has shown that the addition of singlewalled nanotubes (SWNTs) and multi-walled nanotubes (MWNTs) to various polymer matrices have produced significant improvements in strength and stiffness. It has been shown that the modulus of PAni can be increased by up to four times with the addition of small (< 2 %) amounts of nanotubes. Similar improvements in the modulus of actuating polymers may lead to significant increases in the stress generated and work per cycle. Other previous studies have shown that PAni can be wet-spun into continuous fibers and that these may be used as actuators. Isotonic strains of 0.3 % and isometric stresses of 2 MPa were obtained from these fibers when operated in ionic-liquid electrolytes. The aim of the present study was to develop methods for incorporating carbon nanotubes into PAni fibers and to determine the effects on actuator performance at different isotonic loads. A wet-spinning technique was used to prepare the composite fibers. First, the nanotubes (NTs, HiPCO SWNTs from Carbon Nanotechnology, Inc.) were dispersed by sonication for 30 min in a mixture of 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPSA, Aldrich, 99 %) and dichloroacetic acid (DCAA, Merck, 98 %). PAni (Santa Fe Science and Technology, Inc.) and additional AMPSA were then dissolved in the dispersion by high-speed mixing. After degassing, the spinning solution was injected through a narrow outlet using N2 pressure into an acetone coagulation bath. The spun fibers were hand-drawn to approximately five times their original length across a soldering iron wrapped in Teflon tape heated to 100 °C. C O M M U N IC A IO N S

An exact and explicit solution for the valuation of American put options

Abstract: In this paper, an exact and explicit solution of the well-known Black–Scholes equation for the valuation of American put options is presented for the first time. To the best of the author's knowledge, a closed-form analytical formula has never been found for the valuation of American options of finite maturity, although there have been quite a few approximate solutions and numerical approaches proposed. The closed-form exact solution presented here is written in the form of a Taylor's series expansion, which contains infinitely many terms. However, only about 30 terms are actually needed to generate a convergent numerical solution if the solution of the corresponding European option is taken as the initial guess of the solution series. The optimal exercise boundary, which is the main difficulty of the problem, is found as an explicit function of the risk-free interest rate, the volatility and the time to expiration. A key feature of our solution procedure, which is based on the homotopy-analysis method, i...

Comparison of virulence gene profiles of Escherichia coli strains isolated from healthy and diarrheic swine.

Abstract: A combination of uni- and multiplex PCR assays targeting 58 virulence genes (VGs) associated with Escherichia coli strains causing intestinal and extraintestinal disease in humans and other mammals was used to analyze the VG repertoire of 23 commensal E. coli isolates from healthy pigs and 52 clinical isolates associated with porcine neonatal diarrhea (ND) and postweaning diarrhea (PWD). The relationship between the presence and absence of VGs was interrogated using three statistical methods. According to the generalized linear model, 17 of 58 VGs were found to be significant (P < 0.05) in distinguishing between commensal and clinical isolates. Nine of the 17 genes represented by iha, hlyA, aidA, east1, aah, fimH, iroNE. coli, traT, and saa have not been previously identified as important VGs in clinical porcine isolates in Australia. The remaining eight VGs code for fimbriae (F4, F5, F18, and F41) and toxins (STa, STb, LT, and Stx2), normally associated with porcine enterotoxigenic E. coli. Agglomerative hierarchical algorithm analysis grouped E. coli strains into subclusters based primarily on their serogroup. Multivariate analyses of clonal relationships based on the 17 VGs were collapsed into two-dimensional space by principal coordinate analysis. PWD clones were distributed in two quadrants, separated from ND and commensal clones, which tended to cluster within one quadrant. Clonal subclusters within quadrants were highly correlated with serogroups. These methods of analysis provide different perspectives in our attempts to understand how commensal and clinical porcine enterotoxigenic E. coli strains have evolved and are engaged in the dynamic process of losing or acquiring VGs within the pig population.

Repression, Backfire, and The Theory of Transformative Events

Abstract: Repression sometimes can lead to greater movement mobilization: repressive events that are perceived as unjust have the potential to generate enormous public outrage against those seen as responsible. One result of repression-backfire-can contribute to the understanding of the conditions under which some repressive events may become transformative for social movements. Three case studies that highlight the processes involved in backfire are examined: the 1930 Salt March in India, in particular the beatings at Dharasana, that mobilized popular support for independence; the 1991 massacre in Dili, East Timor, which stimulated a massive expansion in international support for East Timorese independence; and the arrest of alternative cancer therapist John Richardson in 1972, which led to a huge growth in the U.S. movement for alternative therapies. The cases generate a preliminary understanding of the potential scope of backfire, the processes involved in backfire, and new hypotheses.

Nanomaterials for lithium-ion rechargeable batteries.

Abstract: In lithium-ion batteries, nanocrystalline intermetallic alloys, nanosized composite materials, carbon nanotubes, and nanosized transition-metal oxides are all promising new anode materials, while nanosized LiCoO2, LiFePO4, LiMn2O4, and LiMn2O4 show higher capacity and better cycle life as cathode materials than their usual larger-particle equivalents. The addition of nanosized metal-oxide powders to polymer electrolyte improves the performance of the polymer electrolyte for all solid-state lithium rechargeable batteries. To meet the challenge of global warming, a new generation of lithium rechargeable batteries with excellent safety, reliability, and cycling life is needed, i.e., not only for applications in consumer electronics, but especially for clean energy storage and for use in hybrid electric vehicles and aerospace. Nanomaterials and nanotechnologies can lead to a new generation of lithium secondary batteries. The aim of this paper is to review the recent developments on nanomaterials and nanotechniques used for anode, cathode, and electrolyte materials, the impact of nanomaterials on the performance of lithium batteries, and the modes of action of the nanomaterials in lithium rechargeable batteries.

The Role of Hybridization in the Evolution of Reef Corals

Abstract: The importance of hybridization in the evolution of plant species is widely accepted, but its contributions to animal species evolution remain less recognized. Here we review evidence that hybridization has contributed to the evolution of reef corals, a group underpinning the coral reef ecosystem. Increasingly threatened by human and climate-related impacts, there is need to understand the evolutionary processes that have given rise to their diversity and contribute to their resilience. Reticulate evolutionary pathways among the ecologically prominent, mass-spawning genus Acropora suggest that hybridization, although rare on ecological timescales, has been instrumental in their diversification on evolutionary timescales. Evidence that coral hybrids colonize marginal habitats distinct from those of parental species’ and that hybridization may be more frequent at peripheral boundaries of species’ ranges supports a role for hybridization in range expansion and adaptation to changing environments. We conclude that outcomes of hybridization are significant for the future resilience of reef corals and warrant inclusion in conservation strategies.

The influence of religion-based workplace spirituality on business leaders' decision-making: An inter-faith study

Abstract: The paper reports the findings of thirteen interviews with prominent Sri Lankan business leaders drawn from Buddhist, Christian, Hindu, and Muslim religious traditions. The in-depth interviews with the leaders were supplemented by documentary sources. When the leaders were asked why they engaged in religion-based workplace spirituality, their responses were often associated with decision-making. Although they had an array of management tools with which to deal with day-to-day management situations, they all indicated that, in ‘difficult’ moments, these tools needed to be complemented by processes by which they connected with the ultimate – variously identified as the transcendent reality, god, or truth that is more powerful, better, and good. The outcomes of decisions, both good and bad, were usually attributed to that connecting experience. The findings suggest that religion plays a significant role in influencing the judgment, emotional and motivational qualities of Sri Lankan leaders' decision-making – in that a frame of reference based on a connection with a transcendent and ultimate reality is likely to be a source of solace, guidance, and inspiration to leaders' critical decision-making.

Incidence and risk factors for hepatitis C seroconversion in injecting drug users in Australia

Abstract: Aims To determine the incidence of hepatitis C virus (HCV) infection and identify risk factors for seroconversion. Design Prospective cohort study. Participants were recruited through direct approaches, street-based outreach, methadone and sexual health clinics and needle and syringe programmes. Setting Urban, regional and rural settings in New South Wales, Australia. Participants Injecting drug users (IDUs) ( n = 584) were screened and tested for exposure to HCV. Between 1999 and 2002 antibody HCV negative IDUs ( n = 368) were enrolled and followed-up every 3–6 months until seroconversion or study completion. Measurements Interviewer-administered baseline and follow- up questionnaires consisted of 131 items and included demographics, drug use and risk behaviour. Approximately 10 cc of whole blood was drawn at each visit. Specimens were stored at − 70C and serology performed using one or two third-generation enzyme-linked immunosorbent assays and polymerase chain reaction testing. Findings Sixtyeight seroconversions were observed and incidence was 30.8 per 100 person-years, with incidence in IDUs injecting < 1 year, 133 per 100 person-years. Independent predictors of seroconversion were female gender, duration of injecting, injecting cocaine, shared use of filters and recruitment strategy. Conclusions Women, new initiates and IDUs recruited via outreach appear to be at increased risk of infection. Results confirm the significance of cocaine injection as a risk factor and provide the first evidence outside North America of the link between shared use of drug preparation equipment and incident HCV infection. Prevention efforts should attempt to raise awareness of the risks associated with drug sharing and, in particular, the role of potentially contaminated syringes in HCV infection.

From destination brand to location brand

Abstract: Destination marketing organisations, often with government support, have traditionally been responsible for promoting their respective locations. A number of authors are now suggesting a review of this responsibility. The claim is that destination marketing and the destination brand have the limitation of being tourism focused only and often preclude major stakeholders in a location. The more holistic approach of location or place brand management is gaining interest. The aim of this paper is to identify the literature calling for reform of destination marketing practices as well as the growing body of literature addressing location brand management. A distinction between destination brand and location brand is made, followed by the identification of potential areas of research relevant to the brand management of locations.