Institution
University of Würzburg
Education•Wurzburg, Bayern, Germany•
About: University of Würzburg is a education organization based out in Wurzburg, Bayern, Germany. It is known for research contribution in the topics: Population & CAS Registry Number. The organization has 31437 authors who have published 62203 publications receiving 2337033 citations. The organization is also known as: Julius-Maximilians-Universität Würzburg & Würzburg University.
Topics: Population, CAS Registry Number, Immune system, Gene, T cell
Papers published on a yearly basis
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University of Cambridge1, University College London2, McGill University3, University of Leicester4, University of Bristol5, University of Copenhagen6, University of London7, Copenhagen University Hospital8, University of Queensland9, University of Washington10, University of Vermont11, Sir Charles Gairdner Hospital12, University of Western Australia13, Ontario Institute for Cancer Research14, University of Würzburg15, ETH Zurich16, University of Edinburgh17, University of Warwick18, Utrecht University19, National Heart Foundation of Australia20, Boston University21, University of Kiel22, University of Lübeck23, University Hospital Regensburg24, King's College London25, Mario Negri Institute for Pharmacological Research26, Wake Forest University27, Karolinska Institutet28, University of Leeds29, Harvard University30, Group Health Cooperative31, McMaster University32, University of Oxford33, University of Glasgow34, Imperial College London35, Medical University of Graz36, University of Ulm37, Goethe University Frankfurt38, Lund University39, Helmholtz Zentrum München40, Robert Koch Institute41, Ludwig Maximilian University of Munich42, Umeå University43, University of Pennsylvania44, Johns Hopkins University45, Clinical Trial Service Unit46, Aga Khan University Hospital47, Robertson Centre for Biostatistics48, Tufts University49, University of Bonn50, Erasmus University Rotterdam51, Karolinska University Hospital52, University of Groningen53, Northwestern University54, University of California, Los Angeles55, Glasgow Royal Infirmary56, Glasgow Clinical Research Facility57
TL;DR: Human genetic data indicate that C reactive protein concentration itself is unlikely to be even a modest causal factor in coronary heart disease.
Abstract: Objective To use genetic variants as unconfounded proxies of C reactive protein concentration to study its causal role in coronary heart disease. Design Mendelian randomisation meta-analysis of ind ...
583 citations
TL;DR: The data obtained demonstrate the heavy metal-dependent expression of different AMF genes in the intra- and extraradical mycelium in plants and fungi under heavy metal stress.
583 citations
TL;DR: The finding that oxidized glutathione is not decreased in Parkinson's disease suggests that the decrease in reduced glutathion is not exclusively the consequence of neuronal loss in the substantia nigra but may indicate a state of oxidative stress.
583 citations
Wellcome Trust Sanger Institute1, National Autonomous University of Mexico2, University of Buenos Aires3, Iowa State University4, University of Zurich5, University of the Republic6, University of Oxford7, Beijing Institute of Genomics8, University of Toronto9, University of Würzburg10, Natural History Museum11, National University of Ireland, Galway12, University of Calgary13, McGill University14
TL;DR: An analysis of tapeworm genome sequences using the human-infective species Echinococcus multilocularis, E. granulosus, Taenia solium and the laboratory model Hymenolepis microstoma offers insights into the evolution of parasitism and identifies new potential drug targets.
Abstract: Tapeworms (Cestoda) cause neglected diseases that can be fatal and are difficult to treat, owing to inefficient drugs. Here we present an analysis of tapeworm genome sequences using the human-infective species Echinococcus multilocularis, E. granulosus, Taenia solium and the laboratory model Hymenolepis microstoma as examples. The 115- to 141-megabase genomes offer insights into the evolution of parasitism. Synteny is maintained with distantly related blood flukes but we find extreme losses of genes and pathways that are ubiquitous in other animals, including 34 homeobox families and several determinants of stem cell fate. Tapeworms have specialized detoxification pathways, metabolism that is finely tuned to rely on nutrients scavenged from their hosts, and species-specific expansions of non-canonical heat shock proteins and families of known antigens. We identify new potential drug targets, including some on which existing pharmaceuticals may act. The genomes provide a rich resource to underpin the development of urgently needed treatments and control.
581 citations
TL;DR: The clinical and laboratory parameters for diagnosing biofilm infections are outlined based on the patient's history, signs and symptoms, microscopic findings, culture-based or culture-independent diagnostic techniques and specific immune responses to identify microorganisms known to causeBiofilm infections.
581 citations
Authors
Showing all 31653 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Peer Bork | 206 | 697 | 245427 |
| Cyrus Cooper | 204 | 1869 | 206782 |
| D. M. Strom | 176 | 3167 | 194314 |
| George P. Chrousos | 169 | 1612 | 120752 |
| David A. Bennett | 167 | 1142 | 109844 |
| Marc W. Kirschner | 162 | 457 | 102145 |
| Josef M. Penninger | 154 | 700 | 107295 |
| William A. Catterall | 154 | 536 | 83561 |
| Rui Zhang | 151 | 2625 | 107917 |
| Niels Birbaumer | 142 | 835 | 77853 |
| Kim Nasmyth | 142 | 294 | 59231 |
| James J. Gross | 139 | 529 | 100206 |
| Michael Schmitt | 134 | 2007 | 114667 |
| Jean-Luc Brédas | 134 | 1026 | 85803 |
| Alexander Schmidt | 134 | 1185 | 83879 |