Institution
University of Zagreb
Education•Zagreb, Grad Zagreb, Croatia•
About: University of Zagreb is a education organization based out in Zagreb, Grad Zagreb, Croatia. It is known for research contribution in the topics: Population & European union. The organization has 21769 authors who have published 50267 publications receiving 783239 citations. The organization is also known as: Zagreb University & Sveučilište u Zagrebu.
Papers published on a yearly basis
Papers
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TL;DR: The toxicokinetic profile of ochratoxin A was studied after the oral or intravenous administration of 50 ng/g b.w. to fish, quail, mouse, rat and monkey.
Abstract: The toxicokinetic profile of ochratoxin A was studied after the oral or intravenous administration of 50 ng/g b.w. to fish, quail, mouse, rat and monkey. The elimination half-life varied from 0.68 h after oral administration to fish, up to 840 h after intravenous administration to monkey. The distribution volume ranged from 57 ml/kg in fish to 1500 ml/kg in quail. The plasma clearance was most rapid in quail and fish, 72 and 58 ml/kg.h, respectively, while it was only 0.17 ml/kg.h in monkey. The bioavailability was as low as 1.6% in fish but as high as 97% in mouse. The binding abilities of ochratoxin A to plasma proteins were also studied. From these data we calculated the free fraction of toxin in plasma, which we found to be less than 0.2% in all species investigated (including man) except fish. A similar but smaller investigation on the toxicokinetics and binding properties of ochratoxin B was also performed. Ochratoxin B was more readily eliminated and had a lower affinity for plasma proteins, which partly may explain its lower toxicity.
254 citations
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30 Jun 2011-Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment
TL;DR: Besides their potential toxicity, biogenic amines are used for the evaluation of hygienic quality of different marine and freshwater species and are the most objective indicators of quality of histidine-poor fish, shellfish and fermented seafood products.
Abstract: Fish, cephalopods and shellfish provide a healthy source of high-quality proteins, essential vitamins, minerals and polyunsaturated fatty acids. The beneficial effects of fish consumption on human health such as protection against coronary heart disease and certain cancer may be offset by fish decomposition and the formation of chemical contaminants such as biogenic amines. There are several toxicological effects of biogenic amines on humans, especially histamine. It is the causative agent of histamine or scombroid fish poisoning which is a significant public health problem. In individuals with diminished histamine detoxification, ingestion of even a low or moderate histamine- or tyramine-containing fish may lead to food intolerance. Biogenic amines such as putrescine, tyramine and cadaverine can potentiate histamine toxicity. Furthermore, dietary polyamine intake should be minimised in some cancer patients. Besides their potential toxicity, biogenic amines are used for the evaluation of hygienic quality ...
254 citations
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TL;DR: The results show that by measuring electric conductivity during the pulses the authors can detect limit permeabilization threshold but not directly permeabilized level, whereas impedance measurements in seconds after the pulse application are not suitable.
253 citations
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TL;DR: In this article, the authors investigated the prospects for realization of the 100% renewable energy system in Macedonia by making use of the EnergyPLAN model and analyzed two renewable scenarios designed for the years 2030 and 2050.
253 citations
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TL;DR: In this paper, the authors proposed an ultra-light, high-resolution Inner Tracking System (ITS) based on monolithic CMOS pixel detectors for detection of heavy-flavour hadrons, and of thermal photons and low-mass di- electrons emitted by the Quark-Gluon Plasma (QGP) at the CERN LHC (Large Hadron Collider).
Abstract: ALICE (A Large Ion Collider Experiment) is studying the physics of strongly interacting matter, and in particular the properties of the Quark–Gluon Plasma (QGP), using proton–proton, proton–nucleus and nucleus–nucleus collisions at the CERN LHC (Large Hadron Collider). The ALICE Collaboration is preparing a major upgrade of the experimental apparatus, planned for installation in the second long LHC shutdown in the years 2018–2019. A key element of the ALICE upgrade is the construction of a new, ultra-light, high- resolution Inner Tracking System (ITS) based on monolithic CMOS pixel detectors. The primary focus of the ITS upgrade is on improving the performance for detection of heavy-flavour hadrons, and of thermal photons and low-mass di- electrons emitted by the QGP. With respect to the current detector, the new Inner Tracking System will significantly enhance the determination of the distance of closest approach to the primary vertex, the tracking efficiency at low transverse momenta, and the read-out rate capabilities. This will be obtained by seven concentric detector layers based on a 50 μm thick CMOS pixel sensor with a pixel pitch of about 30×30 μm2. This document, submitted to the LHCC (LHC experiments Committee) in September 2013, presents the design goals, a summary of the R&D activities, with focus on the technical implementation of the main detector components, and the projected detector and physics performance.
252 citations
Authors
Showing all 22096 results
Name | H-index | Papers | Citations |
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Harry Campbell | 150 | 897 | 115457 |
Joseph R. Ecker | 148 | 381 | 94860 |
Igor Rudan | 142 | 658 | 103659 |
Nikola Godinovic | 138 | 1469 | 100018 |
Ivica Puljak | 134 | 1436 | 97548 |
Damir Lelas | 133 | 1354 | 93354 |
Željko Ivezić | 129 | 344 | 84365 |
Piotr Ponikowski | 120 | 762 | 131682 |
Marin Soljacic | 117 | 764 | 51444 |
Ivan Dikic | 107 | 359 | 52088 |
Ozren Polasek | 102 | 436 | 52674 |
Mordechai Segev | 99 | 729 | 40073 |
Srdan Verstovsek | 96 | 1045 | 38936 |
Segev BenZvi | 95 | 482 | 32127 |
Mirko Planinic | 94 | 467 | 31957 |