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Institution

University of Zagreb

EducationZagreb, Grad Zagreb, Croatia
About: University of Zagreb is a education organization based out in Zagreb, Grad Zagreb, Croatia. It is known for research contribution in the topics: Population & European union. The organization has 21769 authors who have published 50267 publications receiving 783239 citations. The organization is also known as: Zagreb University & Sveučilište u Zagrebu.


Papers
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Journal ArticleDOI
07 Nov 2013-Cell
TL;DR: The alternative Dicer isoform, whose phylogenetic origin demonstrates evolutionary plasticity of RNA-silencing pathways, is the main determinant of endogenous RNAi activity in the mouse female germline.

237 citations

Journal Article
TL;DR: The potential of using bacteriocins of lactic acid bacteria, primarily used as biopreservatives, represents a perspective, alternative antimicrobial strategy for continuously increasing problem with antibiotic resistance.
Abstract: Summary The antimicrobial activity of industrially important lactic acid bacteria as starter cultures and probiotic bacteria is the main subject of this review. This activity has been attributed to the production of metabolites such as organic acids (lactic and acetic acid), hydrogen peroxide, ethanol, diacetyl, acetaldehyde, acetoine, carbon dioxide, reuterin, reutericyclin and bacteriocins. The potential of using bacteriocins of lactic acid bacteria, primarily used as biopreservatives, represents a perspective, alternative antimicrobial strategy for continuously increasing problem with antibiotic resistance. Another strategy in resolving this problem is an application of probiotics for different gastrointestinal and urogenital infection therapies.

237 citations

Journal ArticleDOI
TL;DR: In this article, the authors provide a comprehensive overview of the current research on ESS allocation (ESS sizing and siting), giving a unique insight into issues and challenges of integrating ESS into distribution networks and thus giving framework guidelines for future ESS research.
Abstract: Changes in the electricity business environment, dictated mostly by the increasing integration of renewable energy sources characterised by variable and uncertain generation, create new challenges especially in the liberalised market environment. The role of energy storage systems (ESS) is recognised as a mean to provide additional system security, reliability and flexibility to respond to changes that are still difficult to accurately forecast. However, there are still open questions about benefits these units bring to the generation side, system operators and the consumers. This study provides a comprehensive overview of the current research on ESS allocation (ESS sizing and siting), giving a unique insight into issues and challenges of integrating ESS into distribution networks and thus giving framework guidelines for future ESS research.

237 citations

Journal ArticleDOI
TL;DR: SITBRQ may be used for assessment of the frequency of sitting breaks within desk-based work settings with validity and reliability similar to other self-reports in the field of sedentary behaviour research, but until adequately improved and re-evaluated it should not be used to collect data about the duration of breaks in sitting time.
Abstract: Background Breaks in prolonged sitting may have beneficial cardiometabolic and musculoskeletal health outcomes. Desk-based work settings are an important environment to promote and support breaks in sitting time. However, few studies have reported the psychometric properties of self-report measures to assess the frequency and duration of breaks from sitting. This study examined the concurrent validity and test-retest reliability of the Workplace Sitting Breaks Questionnaire (SITBRQ) designed to assess frequency and duration of breaks in sitting within desk-based work settings.

237 citations

Journal ArticleDOI
TL;DR: Findings indicate that deficiency of UBR1 perturbs the pancreas' acinar cells and other organs, presumably owing to metabolic stabilization of specific substrates of the N-end rule pathway.
Abstract: Johanson-Blizzard syndrome (OMIM 243800) is an autosomal recessive disorder that includes congenital exocrine pancreatic insufficiency, multiple malformations such as nasal wing aplasia, and frequent mental retardation. We mapped the disease-associated locus to chromosome 15q14-21.1 and identified mutations, mostly truncating ones, in the gene UBR1 in 12 unrelated families with Johanson-Blizzard syndrome. UBR1 encodes one of at least four functionally overlapping E3 ubiquitin ligases of the N-end rule pathway, a conserved proteolytic system whose substrates include proteins with destabilizing N-terminal residues. Pancreas of individuals with Johanson-Blizzard syndrome did not express UBR1 and had intrauterine-onset destructive pancreatitis. In addition, we found that Ubr1(-/-) mice, whose previously reported phenotypes include reduced weight and behavioral abnormalities, had an exocrine pancreatic insufficiency, with impaired stimulus-secretion coupling and increased susceptibility to pancreatic injury. Our findings indicate that deficiency of UBR1 perturbs the pancreas' acinar cells and other organs, presumably owing to metabolic stabilization of specific substrates of the N-end rule pathway.

236 citations


Authors

Showing all 22096 results

NameH-indexPapersCitations
Harry Campbell150897115457
Joseph R. Ecker14838194860
Igor Rudan142658103659
Nikola Godinovic1381469100018
Ivica Puljak134143697548
Damir Lelas133135493354
Željko Ivezić12934484365
Piotr Ponikowski120762131682
Marin Soljacic11776451444
Ivan Dikic10735952088
Ozren Polasek10243652674
Mordechai Segev9972940073
Srdan Verstovsek96104538936
Segev BenZvi9548232127
Mirko Planinic9446731957
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023119
2022525
20213,277
20203,360
20193,176
20183,042