Institution
University of Zambia
Education•Lusaka, Lusaka, Zambia•
About: University of Zambia is a education organization based out in Lusaka, Lusaka, Zambia. It is known for research contribution in the topics: Population & Health care. The organization has 2593 authors who have published 4402 publications receiving 122411 citations. The organization is also known as: UNZA.
Topics: Population, Health care, Acquired immunodeficiency syndrome (AIDS), Public health, Tuberculosis
Papers published on a yearly basis
Papers
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TL;DR: As indicated by villous blunting and inflammation on duodenal histology, those with diarrhea and parasites showed the most severe damage and could not implicate mycobacteria or bacterial overgrowth as causes for the enteropathy associated with HIV.
Abstract: To investigate the etiology of chronic diarrhea associated with human immunodeficiency virus (HIV) infection in Lusaka, we studied 63 HIV-positive patients and 36 seronegative controls clinically and endoscopically. Stools were studied for morphology and for opportunist infections. Fifty-five percent of patients seropositive for HIV who presented with a history of chronic diarrhea had parasites; the most common were Cryptosporidium (32%), Isospora belli (16%), and Strongyloides stercoralis (6%). As indicated by villous blunting and inflammation on duodenal histology, those with diarrhea and parasites showed the most severe damage. We could not implicate mycobacteria or bacterial overgrowth as causes for the enteropathy associated with HIV.
92 citations
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TL;DR: All three injectable regimens compare favourably with oral contraceptives in terms of pregnancy and total continuation rates observed in clinical trial settings and for family planning programs, NET-EN (60-day) has the advantage of low pregnancy rates compared to NET- EN (84-day), and a schedule of administration that does not change.
92 citations
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TL;DR: In this article, the knowledge, attitudes, beliefs, and practices of health care workers with respect to epilepsy were investigated in the context of a shortage of physicians in the country and the provision of care for those with epilepsy to nonphysicians who may not be adequately trained for this task.
92 citations
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TL;DR: Prevalence of physical fighting within the last 12 months was comparable to estimates obtained in European countries and found clustering of problem behaviours or experiences among adolescents who reported having engaged in physical violence in the past 12 months.
Abstract: Interpersonal physical violence is an important global public health concern that has received limited attention in the developing world. There is in particular a paucity of data regarding physical violence and its socio-demographic correlates among in-school adolescents in Namibia. We analysed cross-sectional data from the Namibia Global School-Based Health Survey (GSHS) conducted in 2004. We aimed to estimate the prevalence and socio-demographic correlates of physical fighting within the last 12 months. We obtained frequencies of socio-demographic attributes. We also assessed the association between self-reported history of having engaging in a physical fight and a selected list of independent variables using logistic regression analysis. Of the 6283 respondents, 50.6% (55.2% males and 46.2% females) reported having been in a physical fight in the past 12 months. Males were more likely to have been in a physical fight than females (OR = 1.71, 95% CI (1.44, 2.05)). Smoking, drinking alcohol, using drugs and bullying victimization were positively associated with fighting (OR = 1.91, 95% CI (1.49, 2.45); OR = 1.48, 95% CI (1.21, 1.81); OR = 1.55, 95% CI (1.22, 1.81); and OR = 3.12, 95% CI (2.62, 3.72), respectively). Parental supervision was negatively associated with physical fighting (OR = 0.82, 95% CI (0.69, 0.98)). Both male and female substance users (cigarette smoking, alcohol and drug use) were more likely to engage in physical fighting than non-substance users (OR = 3.53, 95% CI (2.60, 4.81) for males and OR = 11.01, 95% CI (7.25, 16.73) for females). Parental supervision was negatively associated with physical fighting (OR = 0.85, 95% CI (0.72, 0.99)). Prevalence of physical fighting within the last 12 months was comparable to estimates obtained in European countries. We also found clustering of problem behaviours or experiences among adolescents who reported having engaged in physical violence in the past 12 months. There is a need to bring adolescent violent behaviour to the fore of the public health agenda in Namibia.
91 citations
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TL;DR: The issue of patient adherence remains challenging when considering the use of ACT, but it should not be used as an argument against the introduction of ACT.
Abstract: Artemisinin-based combination therapy (ACT) is one strategy recommended to increase cure rates in malaria and to contain resistance to Plasmodium falciparum. In the Maheba refugee settlement, children aged 5 years or younger with a confirmed diagnosis of uncomplicated falciparum malaria are treated with the combination of sulphadoxine-pyrimethamine (1 day) and artesunate (3 days). To measure treatment adherence, home visits were carried out the day after the last treatment dose. Patients who had any treatment dose left were considered certainly non-adherent. Other patients' classification was based on the answers to the questionnaire: patients whose caretakers stated the child had received the treatment regimen exactly as prescribed were considered probably adherent; all other patients were considered probably non-adherent. Reasons for non-adherence were assessed. We found 21.2% (95% CI [15.0-28.4]) of the patients to be certainly non-adherent, 39.4% (95% CI [31.6-47.6]) probably non-adherent, and 39.4% (95% CI [31.6-47.6]) probably adherent. Insufficient explanation by the dispenser was identified as an important reason for non-adherence. When considering the use of ACT, the issue of patient adherence remains challenging. However, it should not be used as an argument against the introduction of ACT. For these treatment regimens to remain efficacious on a long-term basis, specific and locally adapted strategies need to be implemented to ensure completion of the treatment.
91 citations
Authors
Showing all 2635 results
Name | H-index | Papers | Citations |
---|---|---|---|
Alimuddin Zumla | 100 | 747 | 43284 |
David Clark | 73 | 652 | 24857 |
Sten H. Vermund | 69 | 606 | 22181 |
Paul A. Kelly | 68 | 208 | 16836 |
Francis Drobniewski | 67 | 293 | 17371 |
Ayato Takada | 67 | 273 | 14467 |
Karl Peltzer | 60 | 880 | 18515 |
Hirofumi Sawa | 55 | 325 | 11735 |
Peter Godfrey-Faussett | 52 | 173 | 8486 |
Igor J. Koralnik | 52 | 197 | 10186 |
Peter Mwaba | 48 | 132 | 7386 |
Alison M. Elliott | 48 | 299 | 7772 |
Kelly Chibale | 47 | 337 | 7713 |
Chihiro Sugimoto | 47 | 325 | 7737 |
Sian Floyd | 47 | 163 | 6791 |