University of Zimbabwe

About: University of Zimbabwe is a education organization based out in Harare, Harare, Zimbabwe. It is known for research contribution in the topics: Population & Acquired immunodeficiency syndrome (AIDS). The organization has 4378 authors who have published 6800 publications receiving 160720 citations. The organization is also known as: UZ & University College of Rhodesia and Nyasaland.

Masculinity as a barrier to men's use of HIV services in Zimbabwe.

Abstract: Background: A growing number of studies highlight men’s disinclination to make use of HIV services. This suggests there are factors that prevent men from engaging with health services and an urgent need to unpack the forms of sociality that determine men’s acceptance or rejection of HIV services. Methods: Drawing on the perspectives of 53 antiretroviral drug users and 25 healthcare providers, we examine qualitatively how local constructions of masculinity in rural Zimbabwe impact on men’s use of HIV services. Results: Informants reported a clear and hegemonic notion of masculinity that required men to be and act in control, to have know-how, be strong, resilient, disease free, highly sexual and economically productive. However, such traits were in direct conflict with the ‘good patient’ persona who is expected to accept being HIV positive, take instructions from nurses and engage in health-enabling behaviours such as attending regular hospital visits and refraining from alcohol and unprotected extra-marital sex. This conflict between local understandings of manhood and biopolitical representations of ‘a good patient’ can provide a possible explanation to why so many men do not make use of HIV services in Zimbabwe. However, once men had been counselled and had the opportunity to reflect upon the impact of ART on their productivity and social value, it was possible for some to construct new and more ART-friendly versions of masculinity. Conclusion: We urge HIV service providers to consider the obstacles that prevent many men from accessing their services and argue for community-based and driven initiatives that facilitate safe and supportive social spaces for men to openly discuss social constructions of masculinity as well as renegotiate more health-enabling masculinities.

Trichomonas vaginalis Infection and Human Immunodeficiency Virus Acquisition in African Women

Abstract: Trichomoniasis vaginalis is the most common nonviral sexually transmitted infection (STI) worldwide with a particularly high prevalence in regions of human immunodeficiency virus (HIV) endemicity. However its impact as a cofactor for HIV acquisition is poorly understood. Samples from 213 women who experienced HIV seroconversion (cases) during a longitudinal study involving 4450 women in Uganda and Zimbabwe were matched with samples from HIV-uninfected women (controls). All samples underwent polymerase chain reaction (PCR) analysis for Trichomonas vaginalis DNA. For cases analyzed samples were from the visit in which HIV seroconversion was detected and the visit preceding detection of seroconversion; for controls one analyzed sample was from the visit matched by follow-up duration to the cases seroconversion visit and the other sample was from the visit immediately preceding the matched visit. The prevalence of T. vaginalis infection before HIV infection was 11.3% in cases and 4.5% in controls (P = .002). In multivariable analysis controlling for hormonal contraception other STIs behavioral and demographic factors the adjusted odds ratio for HIV acquisition was 2.74 (95% confidence interval 1.25-6.00) for T. vaginalis-positive cases. The presence of behavioral risk factors for HIV infection study recruitment from a referral population at high-risk for HIV primary sex partner-associated risk for HIV infection and herpes simplex virus type 2 seropositivity were also predictive of incident HIV infection. T. vaginalis infection is strongly associated with an increased risk for HIV infection in this general population of African women. Given the high prevalence of T. vaginalis infection in HIV-endemic areas T. vaginalis control may have a substantial impact on preventing HIV acquisition among women. (authors)

Iron overload in Africa: Interaction between a gene and dietary iron content

Abstract: Background and Methods. In contrast to hemochromatosis, which in white populations is inherited through a gene linked to the HLA locus, iron overload in sub-Saharan Africa is believed to result solely from increased dietary iron derived from traditional home-brewed beer. To examine the hypothesis that African iron overload also involves a genetic factor, we used likelihood analysis to test for an interaction between a gene (the hypothesized iron-loading locus) and an environmental factor (increased dietary iron) that determines transferrin saturation and unsaturated iron-binding capacity. We studied 236 members of 36 African families chosen because they contained index subjects with iron overload. Linkage to the HLA region was tested with use of lod scores. Results. In the index subjects, increased iron was present in both hepatocytes and cells of the mononuclearphagocyte system. Among family members with increased dietary iron due to the consumption of traditional beer, transferrin saturation in...

Crustal structure beneath southern Africa and its implications for the formation and evolution of the Kaapvaal and Zimbabwe cratons

Abstract: The formation of Archean crust appears to in- volve processes unique to early earth history. Initial results from receiver function analysis of crustal structure beneath 81 broadband stations deployed across southern Africa re- vealsignicantdierences inthenatureof thecrustandthe crust-mantle boundary between Archean and post-Archean geologic terranes. With the notable exception of the colli- sional Limpopo belt, where the crust is thick and the Moho complex, the crust beneath undisturbed Archean craton is typically thin ( 35{40 km), unlayered, and characterized byastrongvelocitycontrastacrossarelativelysharpMoho. Thiscrustalstructurecontrastsmarkedlywiththatbeneath post-ArcheanterranesandbeneathArcheanregionsaected bylarge-scaleProterozoicevents(theBushveldcomplexand the Okwa/Magondi belts), where the crust tends to be rel- atively thick (45{50 km) and the Moho is complex.