University of Zimbabwe

About: University of Zimbabwe is a education organization based out in Harare, Harare, Zimbabwe. It is known for research contribution in the topics: Population & Acquired immunodeficiency syndrome (AIDS). The organization has 4378 authors who have published 6800 publications receiving 160720 citations. The organization is also known as: UZ & University College of Rhodesia and Nyasaland.

Termitaria as browsing hotspots for African megaherbivores in miombo woodland

Abstract: Thirteen termite mounds and 13 similar-sized control plots were surveyed in central Zimbabwe in order to study large mammalian browsing and vegetation characteristics. The mounds supported almost twice as many tree species as the control plots and the woody vegetation was denser on mounds compared with the woodland plots. Species of woody plants were recorded along with the percentage of branches browsed (cumulative browsing score) by black rhino, Diceros bicornis, elephant, Loxodonta africana and other browsers combined. In addition we measured how the cumulative browsing score on three woody plant species, Acacia nilotica, Colophospermum mopane and Dichrostachys cinerea, which were common both on and off mounds, was related to the distance from mound centre. Both black rhino and elephant cumulative browsing scores were significantly higher on the mound plants compared with the woodland plots. Cumulative browsing score was negatively related to distance from the mound centre for Dichrostachys cinerea, Colophospermum mopane and Acacia nilotica. We propose that termite mound construction in miombo woodland contributes to sustaining populations of megaherbivores and perhaps some woody species in these areas.

Incident and prevalent herpes simplex virus type 2 infection increases risk of HIV acquisition among women in Uganda and Zimbabwe

Abstract: An association has been demonstrated between herpes simplex type 2 (HSV-2) and HIV infection among men but prospective studies in women have yielded mixed results. The objective was to estimate the effects of prevalent and incident HSV-2 infection on subsequent HIV acquisition among women in two African countries. Design: Prospective cohort study. HSV-2 and HIV serostatus were evaluated at enrollment and quarterly for 15-24 months among 4531 sexually active HIV-uninfected women aged 18-35 years from Uganda and Zimbabwe. The association between prior HSV-2 infection and HIV acquisition was estimated using a marginal structural discrete survival model adjusted for covariates. HSV-2 seroprevalence at enrollment was 52% in Uganda and 53% in Zimbabwe; seroincidence during follow-up was 9.6 and 8.8/100 person-years in Uganda and Zimbabwe respectively. In Uganda the hazard ratio (HR) for HIV was 2.8 [95% confidence interval (CI) 1.5-5.3] among women with seroprevalent HSV-2 and 4.6 (95% CI 1.6-13.1) among women with seroincident HSV-2 adjusted for confounding. In Zimbabwe the HR for HIV was 4.4 (95% CI 2.7-7.2) among women with seroprevalent HSV-2 and 8.6 (95% CI 4.3-17.1) among women with seroincident HSV-2 adjusted for confounding. The population attributable risk percent for HIV due to prevalent and incident HSV-2 infection was 42% in Uganda and 65% in Zimbabwe. HSV-2 plays an important role in the acquisition of HIV among women. Efforts to implement known HSV-2 control measures as well as identify additional measures to control HSV-2 are urgently needed to curb the spread of HIV. (authors)

On farm evaluation of the effect of low cost drip irrigation on water and crop productivity compared to conventional surface irrigation system

Abstract: This on-farm research study was carried out at Zholube irrigation scheme in a semi-arid agro tropical climate of Zimbabwe to determine how low cost drip irrigation technologies compare with conventional surface irrigation systems in terms of water and crop productivity. A total of nine farmers who were practicing surface irrigation were chosen to participate in the study. The vegetable English giant rape ( Brassica napus ) was grown under the two irrigation systems with three fertilizer treatments in each system: ordinary granular fertilizer, liquid fertilizer (fertigation) and the last treatment with no fertilizer. These trials were replicated three times in a randomized block design. Biometric parameters of leaf area index (LAI) and fresh weight of the produce, water use efficiency (WUE) were used to compare the performance of the two irrigation systems. A water balance of the inflows and outflows was kept for analysis of WUE. The economic profitability and the operation, maintenance and management requirements of the different systems were also evaluated. There was no significant difference in vegetable yield between the irrigation systems at 8.5 ton/ha for drip compared to 7.8 ton/ha in surface irrigation. There were significant increases in yields due to use of fertilizers. Drip irrigation used about 35% of the water used by the surface irrigation systems thus giving much higher water use efficiencies. The leaf area indices were comparable in both systems with the same fertilizer treatment ranging between 0.05 for surface without fertilizer to 6.8 for low cost drip with fertigation. Low cost drip systems did not reflect any labour saving especially when manually lifting the water into the drum compared to the use of siphons in surface irrigation systems. The gross margin level for surface irrigation was lower than for low cost drip irrigation but the gross margin to total variable cost ratio was higher in surface irrigation systems, which meant that surface irrigation systems gave higher returns per variable costs incurred. It was concluded that low cost drip systems achieved water saving of more than 50% compared to surface irrigation systems and that it was not the type of irrigation system that influenced the yield of vegetables significantly but instead it is the type of fertilizer application method that contribute to the increase in the yield of vegetables. It was recommended that low cost technologies should be used in conjunction with good water and nutrient management if higher water and crop productivity are to be realized than surface irrigation systems.

Mother to child transmission of HIV among Zimbabwean women who seroconverted postnatally: prospective cohort study.

Abstract: Objectives To estimate the rates and timing of mother to infant transmission of HIV associated with breast feeding in mothers who seroconvert postnatally, and their breast milk and plasma HIV loads during and following seroconversion, compared with women who tested HIV positive at delivery. Design Prospective cohort study. Setting Urban Zimbabwe. Participants 14 110 women and infants enrolled in the Zimbabwe Vitamin A for Mothers and Babies (ZVITAMBO) trial (1997-2001). Main outcome measures Mother to child transmission of HIV, and breast milk and maternal plasma HIV load during the postpartum period. Results Among mothers who tested HIV positive at baseline and whose infant tested HIV negative with polymerase chain reaction (PCR) at six weeks (n=2870), breastfeeding associated transmission was responsible for an average of 8.96 infant infections per 100 child years of breast feeding (95% CI 7.92 to 10.14) and varied little over the breastfeeding period. Breastfeeding associated transmission for mothers who seroconverted postnatally (n=334) averaged 34.56 infant infections per 100 child years (95% CI 26.60 to 44.91) during the first nine months after maternal infection, declined to 9.50 (95% CI 3.07 to 29.47) during the next three months, and was zero thereafter. Among women who seroconverted postnatally and in whom the precise timing of infection was known (≤90 days between last negative and first positive test; n=51), 62% (8/13) of transmissions occurred in the first three months after maternal infection and breastfeeding associated transmission was 4.6 times higher than in mothers who tested HIV positive at baseline and whose infant tested HIV negative with PCR at six weeks. Median plasma HIV concentration in all mothers who seroconverted postnatally declined from 5.0 log10 copies/mL at the last negative enzyme linked immunosorbent assay (ELISA) to 4.1 log10 copies/mL at 9-12 months after infection. Breast milk HIV load in this group was 4.3 log10 copies/mL 0-30 days after infection, but rapidly declined to 2.0 log10 copies/mL and Conclusions Breastfeeding associated transmission is high during primary maternal HIV infection and is mirrored by a high but transient peak in breast milk HIV load. Around two thirds of breastfeeding associated transmission by women who seroconvert postnatally may occur while the mother is still in the “window period” of an antibody based test, when she would test HIV negative using one of these tests. Trial registration Clinical trials.gov NCT00198718.

Barriers and incentives to orphan care in a time of AIDS and economic crisis: a cross-sectional survey of caregivers in rural Zimbabwe

Abstract: Africa is in an orphan-care crisis. In Zimbabwe, where one-fourth of adults are HIV-positive and one-fifth of children are orphans, AIDS and economic decline are straining society's ability to care for orphans within their extended families. Lack of stable care is putting thousands of children at heightened risk of malnourishment, emotional underdevelopment, illiteracy, poverty, sexual exploitation, and HIV infection, endangering the future health of the society they are expected to sustain. To explore barriers and possible incentives to orphan care, a quantitative cross-sectional survey in rural eastern Zimbabwe asked 371 adults caring for children, including 212 caring for double orphans, about their well-being, needs, resources, and perceptions and experiences of orphan care. Survey responses indicate that: 1) foster caregivers are disproportionately female, older, poor, and without a spouse; 2) 98% of non-foster caregivers are willing to foster orphans, many from outside their kinship network; 3) poverty is the primary barrier to fostering; 4) financial, physical, and emotional stress levels are high among current and potential fosterers; 5) financial need may be greatest in single-orphan AIDS-impoverished households; and 6) struggling families lack external support. Incentives for sustainable orphan care should focus on financial assistance, starting with free schooling, and development of community mechanisms to identify and support children in need, to evaluate and strengthen families' capacity to provide orphan care, and to initiate and support placement outside the family when necessary.