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Institution

University of Zurich

EducationZurich, Switzerland
About: University of Zurich is a education organization based out in Zurich, Switzerland. It is known for research contribution in the topics: Population & Transplantation. The organization has 50842 authors who have published 124042 publications receiving 5304521 citations. The organization is also known as: UZH & Uni Zurich.


Papers
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Journal ArticleDOI
TL;DR: Disruption of function of left, but not right, lateral prefrontal cortex with low-frequency repetitive transcranial magnetic stimulation increased choices of immediate rewards over larger delayed rewards, providing causal evidence for a neural lateral-prefrontal cortex–based self-control mechanism in intertemporal choice.
Abstract: Disruption of function of left, but not right, lateral prefrontal cortex (LPFC) with low-frequency repetitive transcranial magnetic stimulation (rTMS) increased choices of immediate rewards over larger delayed rewards. rTMS did not change choices involving only delayed rewards or valuation judgments of immediate and delayed rewards, providing causal evidence for a neural lateral-prefrontal cortex-based self-control mechanism in intertemporal choice.

584 citations

Journal ArticleDOI
TL;DR: In this article, the authors propose to construct a studentized time series bootstrap confidence interval for the difference of the Sharpe ratios and declare the two ratios different if zero is not contained in the obtained interval.

584 citations

Journal ArticleDOI
TL;DR: In this article, a cosmological N-body/smooth particle hydrodynamic simulation of extreme dynamic range in which a close analog of a Milky Way disk galaxy arises naturally is presented.
Abstract: Simulations of the formation of late-type spiral galaxies in a cold dark matter ({Lambda}CDM) universe have traditionally failed to yield realistic candidates. Here we report a new cosmological N-body/smooth particle hydrodynamic simulation of extreme dynamic range in which a close analog of a Milky Way disk galaxy arises naturally. Named 'Eris', the simulation follows the assembly of a galaxy halo of mass M{sub vir} = 7.9 Multiplication-Sign 10{sup 11} M{sub Sun} with a total of N = 18.6 million particles (gas + dark matter + stars) within the final virial radius, and a force resolution of 120 pc. It includes radiative cooling, heating from a cosmic UV field and supernova explosions (blastwave feedback), a star formation recipe based on a high gas density threshold (n{sub SF} = 5 atoms cm{sup -3} rather than the canonical n{sub SF} = 0.1 atoms cm{sup -3}), and neglects any feedback from an active galactic nucleus. Artificial images are generated to correctly compare simulations with observations. At the present epoch, the simulated galaxy has an extended rotationally supported disk with a radial scale length R{sub d} = 2.5 kpc, a gently falling rotation curve with circular velocity at 2.2 disk scale lengths of V{sub 2.2}more » = 214 km s{sup -1}, an i-band bulge-to-disk ratio B/D = 0.35, and a baryonic mass fraction within the virial radius that is 30% below the cosmic value. The disk is thin, has a typical H I-to-stellar mass ratio, is forming stars in the region of the {Sigma}{sub SFR}-{Sigma}{sub HI} plane occupied by spiral galaxies, and falls on the photometric Tully-Fisher and the stellar-mass-halo-virial-mass relations. Hot (T > 3 Multiplication-Sign 10{sup 5} K) X-ray luminous halo gas makes up only 26% of the universal baryon fraction and follows a 'flattened' density profile {proportional_to}r{sup -1.13} out to r = 100 kpc. Eris appears then to be the first cosmological hydrodynamic simulation in which the galaxy structural properties, the mass budget in the various components, and the scaling relations between mass and luminosity are all consistent with a host of observational constraints. A twin simulation with a low star formation density threshold results in a galaxy with a more massive bulge and a much steeper rotation curve, as in previously published work. A high star formation threshold appears therefore key in obtaining realistic late-type galaxies, as it enables the development of an inhomogeneous interstellar medium where star formation and heating by supernovae occur in a clustered fashion. The resulting outflows at high redshifts reduce the baryonic content of galaxies and preferentially remove low-angular-momentum gas, decreasing the mass of the bulge component. Simulations of even higher resolution that follow the assembly of galaxies with different merger histories shall be used to verify our results.« less

583 citations

Journal ArticleDOI
TL;DR: The demonstration of the effectiveness of IPS in widely differing labour market and welfare contexts confirms this service to be an effective approach for vocational rehabilitation in mental health that deserves investment and further investigation.

583 citations

Journal ArticleDOI
TL;DR: The role of salivary alpha-amylase as a promising candidate for a reliable, noninvasive marker of psychosocial stress is discussed and found to corroborate findings from other studies that showed increased levels of alpha-Amylase before and after psychological stress.

582 citations


Authors

Showing all 51384 results

NameH-indexPapersCitations
Richard A. Flavell2311328205119
Peer Bork206697245427
Thomas C. Südhof191653118007
Stuart H. Orkin186715112182
Ruedi Aebersold182879141881
Tadamitsu Kishimoto1811067130860
Stanley B. Prusiner16874597528
Yang Yang1642704144071
Tomas Hökfelt158103395979
Dan R. Littman157426107164
Hans Lassmann15572479933
Matthias Egger152901184176
Lorenzo Bianchini1521516106970
Robert M. Strieter15161273040
Ashok Kumar1515654164086
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023265
20221,039
20218,997
20208,398
20197,336
20186,832