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Institution

Uppsala University

EducationUppsala, Sweden
About: Uppsala University is a education organization based out in Uppsala, Sweden. It is known for research contribution in the topics: Population & Insulin. The organization has 36485 authors who have published 107509 publications receiving 4220668 citations. The organization is also known as: Uppsala universitet & uu.se.
Topics: Population, Insulin, Thin film, Poison control, Gene


Papers
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Journal ArticleDOI
Joakim Kreutz1
TL;DR: In this article, the authors present new data on the start and end dates and the means of termination for armed conflicts, 1946-2005, which contribute to quantitative research on conflict resolution and recu...
Abstract: This article presents new data on the start and end dates and the means of termination for armed conflicts, 1946—2005. These data contribute to quantitative research on conflict resolution and recu...

452 citations

Journal ArticleDOI
TL;DR: The experimental characterization of sRNAs analyzed here suggests that the definition of an sRNA is more complex than previously assumed, and shows that two recently identified s RNAs interact, resulting in RNase III-dependent cleavage.
Abstract: Recent bioinformatics-aided searches have identified many new small RNAs (sRNAs) in the intergenic regions of the bacterium Escherichia coli. Here, a shot-gun cloning approach (RNomics) was used to generate cDNA libraries of small sized RNAs. Besides many of the known sRNAs, we found new species that were not predicted previously. The present work brings the number of sRNAs in E.coli to 62. Experimental transcription start site mapping showed that some sRNAs were encoded from independent genes, while others were processed from mRNA leaders or trailers, indicative of a parallel transcriptional output generating sRNAs co-expressed with mRNAs. Two of these RNAs (SroA and SroG) consist of known (THI and RFN) riboswitch elements. We also show that two recently identified sRNAs (RyeB and SraC/RyeA) interact, resulting in RNase III-dependent cleavage. To the best of our knowledge, this represents the first case of two non-coding RNAs interacting by a putative antisense mechanism. In addition, intracellular metabolic stabilities of sRNAs were determined, including ones from previous screens. The wide range of half-lives ( 32 min) indicates that sRNAs cannot generally be assumed to be metabolically stable. The experimental characterization of sRNAs analyzed here suggests that the definition of an sRNA is more complex than previously assumed.

452 citations

Journal ArticleDOI
TL;DR: The Swedish Two-County Trial as mentioned in this paper is a randomized controlled trial of invitation to breast cancer screening, with 133,000 women randomized between 1977 and 1979 to regular invitation to screening or to no invitation.

452 citations

Journal ArticleDOI
Georges Aad1, Brad Abbott2, Jalal Abdallah3, A. A. Abdelalim4  +3034 moreInstitutions (179)
TL;DR: In this article, a search for squarks and gluinos in final states containing jets, missing transverse momentum and no electrons or muons is presented, and the data were recorded by the ATLAS experiment in sqrt(s) = 7 TeV proton-proton collisions at the Large Hadron Collider.

452 citations

Journal ArticleDOI
TL;DR: The K562 cell expressed the major red cell sialoglycoprotein, glycophorin, on its surface as shown by immuno‐fluorescence and by immuneprecipitation from labelled membrane preparations, and it is concluded that the K562 is a human erythroleukemic line.
Abstract: We have studied the surface membrane properties of the human leukemic cell line K562 which previously has been reported to represent an early stage of granulocyte maturation. The surface glycoprotein pattern of the K562 cells obtained after galactose oxidase-NaB[3H]4 labelling and slab gel electrophoresis shows striking similarities with that of normal erythrocytes but is completely different from the patterns of normal and malignant cells of various stages of the myeloblast to granulocyte differentiation. Moreover, the K562 cell expressed the major red cell sialoglycoprotein, glycophorin, on its surface as shown by immunofluorescence and by immunoprecipitation from labelled membrane preparations. As glycophorin is exclusively found on erythroid cells in human bone marrow we conclude that the K562 is a human erythroleukemic line.

452 citations


Authors

Showing all 36854 results

NameH-indexPapersCitations
Zhong Lin Wang2452529259003
Lewis C. Cantley196748169037
Darien Wood1602174136596
Kaj Blennow1601845116237
Christopher J. O'Donnell159869126278
Tomas Hökfelt158103395979
Peter G. Schultz15689389716
Frederik Barkhof1541449104982
Deepak L. Bhatt1491973114652
Svante Pääbo14740784489
Jan-Åke Gustafsson147105898804
Hans-Olov Adami14590883473
Hermann Kolanoski145127996152
Kjell Fuxe142147989846
Jan Conrad14182671445
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023240
2022643
20216,079
20205,811
20195,393
20185,067