Showing papers by "Utrecht University published in 1975"
TL;DR: It is concluded that the lipid packing in the outer monolayer of the erythrocyte membrane is comparable with a lateral surface pressure between 31 and 34.8 dynes/cm.
537 citations
TL;DR: The present study demonstrates that induction of excessive grooming is dose-dependent and independent of the endocrine system, and structure-activity studies show that ACTH1–24, ACTh1–16-NH2, ACTH 1–16, α-MSH and βp- MSH are equipotent.
386 citations
TL;DR: Evidence is presented that the unique properties of the enzyme itself, rather than possible contaminations in the purified preparation, are responsible for the observed haemolytic effect.
340 citations
TL;DR: The quantitative analysis by gas chromatography of monosaccharides present in glycoproteins and glycopeptides using methanolysis, followed by re-N-acetylation and trimethylsilylation gives rise to several peaks for each monosACcharide, which provide for the unambiguous interpretation of the gas chromatograms obtained in the application of this g.l.c.c-mass spectrometry method.
Abstract: The quantitative analysis by gas chromatography of monosaccharides present in glycoproteins and glycopeptides using methanolysis, followed by re-N-acetylation and trimethylsilylation, gives rise to several peaks for each monosaccharide. The identity of these peaks for xylose, fucose, mannose, galactose, glucose, N-acetylglucosamine, N-acetylgalactosamine and N-acetylneuraminic acid was established for alpha- and beta-methyl pyranosides and furanosides by combined g.l.c.-mass spectrometry and proton-magnetic-resonance spectroscopy. These data provide for the unambiguous interpretation of the gas chromatograms obtained in the application of this g.l.c. method, and supply basic information for the further application of mass spectrometry in this field.
327 citations
TL;DR: It is proposed that the enzyme with iron in the ferric state is the active species in the aerobic and anaerobic reaction of soybean lipoxygenase-1.
285 citations
TL;DR: It is concluded that the increased permeability at the transition temperature cannot be ascribed to "macroscopic" rupture of the liposomal membrane, and the maximum permeability in the vicinity of the Tc is discussed in terms of probability and size distribution of statistical pore formation at the boundaries of liquid and solid domains.
283 citations
226 citations
TL;DR: Saturated and unsaturated phosphatidylcholines, dispersed as liposomes in water, can be hydrolysed by phospholipase A2 from pig pancreas and hydrolysis is inhibited by the presence of cholesterol in liposome prepared of saturated phosphatIDylcholine.
220 citations
TL;DR: Results indicate the importance of intraventricularly released vasopressin on memory processes involved in the maintenance of behavioral homeostasis as indicated by the virtual absence of vasoppressin in the urine.
202 citations
195 citations
TL;DR: In this paper, the position of the charge transfer band of Eu3+ in the absorption spectra of a number of oxides is discussed and it is shown that this position is more or less fixed in octahedral VI coordination and that it varies in VIII and XII coordinations as a function of the effective ionic radius of the relevant host lattice ion.
TL;DR: The present study aims at further identifying the interaction of ACTH-like peptides and rat brain opiate receptors in vitro and finds the sequence ACTH4-10 is crucial with respect to affinity since it is the shortest sequence to inhibit the binding of [ 3H]-dihydromorphine and [3H]-naltrexone to these receptors.
TL;DR: The consequences of assuming weak and e.m. forces constitute a gauge field theory, and there are no heavy leptons, are investigated in this article, where a particular Higgs system containing two multiplets is studied in detail.
TL;DR: Differences between HO-DI and Wistar rats in open field behavior, in response threshold to electric footshock, and in a number of somatic endocrine parameters are reported and discussed.
TL;DR: The apatite structure contains two different sites for the larger cations and it is shown that the principle of local charge compensation can predict the site occupation as mentioned in this paper, which is especially important for an interpretation of the luminescence properties of a number of apatites.
TL;DR: In this article, the Yakubovsky four-body equations for the 0+state were solved in the boundstate region for the case of local central forces of the Yukawa type, using the Hilbert-Schmidt expansion.
TL;DR: There is a correlation between the calorimetric data and the permeability properties of dimyristoyl phosphatidylglycerol-containing bilayers with respect to the influence of Ca2+ and Mg2+.
TL;DR: It is concluded that the H 5ts125 gene product and possibly also the H5ts36 gene product are required for the initiation of new rounds of replication and the potential role in initiation of the adenovirus-specific DNA binding protein, which is coded for by the H3H]thymidine gene, is discussed.
TL;DR: A survey of biologically relevant mathematical results available on algorithmic systems modelled by algorithmic rules for multicellular organisms, thus defining a hierarchy of language families.
TL;DR: In this article, the electrical conductivity of In2O3 has been measured up to 1400°C in air and the temperature dependence of the conductivity at high temperatures yields an activation energy of 1.5 ± 0.1 eV.
TL;DR: Specific receptor binding of estradiol (E2) and dihydrotestosterone (DHT) was studied in human myometrial tissue and in human mammary cancer tissue to find receptors were found for both E2 and DHT.
Abstract: Specific receptor binding of estradiol (E2) and dihydrotestosterone (DHT) was studied in human myometrial tissue and in human mammary cancer tissue. The inhibition of binding for E2 and DHT by E2, testosterone (T), DHT, dehydroepiandosterone (DHEA), dehydroepiandrosteronesulfate (DHEA-S), androstenedione (A) and 5-androstene-3β,17β-diol (Adiol) was tested with the use of dextran-coated charcoal separation of bound and free E2, respectively, and DHT. The percentage of binding inhibition was calculated with reference to the inhibition obtained with nafoxidine in a molar concentration ratio of 1,000 for E2 binding, respectively, with cyproterone acetate in a molar concentration ratio of 10,000 for DHT binding. In 15 samples of myometrium tested, receptors were found for both E2 and DHT. From 19 samples of mammary carcinoma tissue one showed no binding activity, three samples did bind E2 only, five samples DHT only, and ten samples showed binding of both steroids. A 50% inhibition of E2 binding, in myometrial...
TL;DR: In this article, aluminum nitrate solutions were titrated with alkali (NaOH or KOH) over a temperature range of 24°C to 90°C, and a homogeneous distribution of added base was achieved by: (i) in situ decomposition of urea (90°C); and (ii) injection through a capillary submerged in the agitated salt solution.
TL;DR: In this paper, the position of the first charge transfer band is fixed for the metal ion in an oxygen coordination of VI, but varies in VIII coordination as a function of the host lattice.
TL;DR: The analytical structure of the hydrodynamic frequencies for the sound, heat, and shear modes and of hydrodynamics equations for a monatomic fluid are discussed in this article.
Abstract: The analytic structure of the hydrodynamic frequenciesz(k) for the sound, heat, and shear modes and of the hydrodynamic equations for a monatomic fluid are discussed on the basis of the mode-mode coupling theory. It is shown that the hydrodynamic frequencies depend on the wave numberk, for smallk, asz(k) = ak + bk
2 +
$$z(k) = ak + bk^2 + \sum
olimits_{n = 1}^\infty {c_n k^{3 - 2^{ - n} } } $$
and that some of the correlation functions that appear in the Fourier-Laplace transforms of the hydrodynamic equations contain branch point singularities. The implications of these results for the derivation of linear hydrodynamic equations, such as the Burnett equations, and for the long-time behavior of time correlation functions are discussed.
TL;DR: It is shown that each everywhere growing DIL language is the image under a coding of an everywhere growing (uniform)DOL language, which enable us to solve the subword complexity problems for developmental languages with interactions.
TL;DR: A number of O-acetylated N-acylneuraminic acids isolated from submandibular glands of cow and horse and from horse erythrocytes, have been characterized by mass spectrometry on the basis of the typical fragmentation patterns of the pertrimethylsilyl derivatives of the methyl esters of the compounds.
01 Dec 1975-Journal of Comparative Physiology A-neuroethology Sensory Neural and Behavioral Physiology
TL;DR: In this paper, it was shown that Propionic acid is formed in equal amounts as succinate (26 μmol g−1 dry weight) together with small amounts of acetate (2 μmolg−1dry weight) during 72 h under N2.
Abstract: 1.
Mytilus edulis L. accumulates VFA during anaerobiosis.
2.
Propionic acid is formed in equal amounts as succinate (26 μmol g−1 dry weight), together with small amounts of acetate (2 μmol g−1 dry weight) during 72 h under N2.
3.
Under aerobic conditions acetate is the only free VFA present in appreciable amounts (12 μmol g−1 dry weight).
4.
About 8 μmol g−1 dry weight of esterified VFA are present in total lipid extracts.
5.
No significant increase in esterification to glycerol-3-phosphate takes place during 72h of anoxia.
TL;DR: In this paper, it was shown that spontaneous symmetry treaking implies a finite cosmological term in the Einstein equation for gravity, and the present theories of weak and e.m. interactions disagree violently with the experimental limit on such a finite term unless an ad-hoc counter curvature is introduced.
Abstract: It is noted that spontaneous symmetry treaking implies
a finite cosmological term in the Einstein equation for
gravity. The present theories of weak and e.m. interactions
disagree violently with the experimental limit on such a
term unless an ad-hoc counter curvature is introduced.
TL;DR: This chapter presents several experiments that indicate that the central hypotensive effect of L-DOPA (L- 3,4-dihydroxyphenylalanin) may be related to an increase of brain stem noradrenaline level, and investigates the cardiovascular effect of bilateral electrolytic brain stem lesions at the level of the obex in rats anesthetized with ether.
Abstract: Publisher Summary This chapter presents several experiments that indicate that the central hypotensive effect of L-DOPA (L- 3,4-dihydroxyphenylalanin) may be related to an increase of brain stem noradrenaline level. Depletion of brain noradrenaline in neonate or adult rats by intraventricular administration of 6-hydroxydopamine did not affect blood pressure. The hypotensive effect of L-DOPA has also been shown in rats, dogs and cats. Inhibition of extracerebral decarboxylase activity to prevent the peripheral effects of dopamine and noradrenaline, which generate from L-DOPA, is required for the expression of the hypotensive effect of L-DOPA in the rat. A number of experiments were performed to investigate whether low levels of brain noradrenaline would lead to opposite effects. In addition, the chapter also studies the cardiovascular effect of bilateral electrolytic brain stem lesions at the level of the obex in rats anesthetized with ether. Blood pressure in the conscious rats was recorded from a permanent indwelling iliac cannula. Lesioning this area was followed by an acute and severe hypertension.
TL;DR: Kinetic data suggest, that the initial presence of more than a loo-fold molar excess of product hydroperoxide over enzyme is necessary to immediately attain the maximum reaction rate, and that, besides the effect of EPR, this could also affect the reaction rate of lipoxygenase-1.