Utrecht University

About: Utrecht University is a education organization based out in Utrecht, Utrecht, Netherlands. It is known for research contribution in the topics: Population & Poison control. The organization has 58176 authors who have published 139351 publications receiving 6214282 citations. The organization is also known as: UU & Universiteit Utrecht.

Review of AdS/CFT Integrability: An Overview

Abstract: This is the introductory chapter of a review collection on integrability in the context of the AdS/CFT correspondence. In the collection we present an overview of the achievements and the status of this subject as of the year 2010.

Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia

Abstract: Background In 1994, an International Task Force proposed criteria for the clinical diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) that facilitated recognition and interpretation of the frequently nonspecific clinical features of ARVC/D. This enabled confirmatory clinical diagnosis in index cases through exclusion of phenocopies and provided a standard on which clinical research and genetic studies could be based. Structural, histological, electrocardiographic, arrhythmic, and familial features of the disease were incorporated into the criteria, subdivided into major and minor categories according to the specificity of their association with ARVC/D. At that time, clinical experience with ARVC/D was dominated by symptomatic index cases and sudden cardiac death victims–the overt or severe end of the disease spectrum. Consequently, the 1994 criteria were highly specific but lacked sensitivity for early and familial disease. Methods and Results Revision of the diagnostic criteria provides guidance on the role of emerging diagnostic modalities and advances in the genetics of ARVC/D. The criteria have been modified to incorporate new knowledge and technology to improve diagnostic sensitivity, but with the important requisite of maintaining diagnostic specificity. The approach of classifying structural, histological, electrocardiographic, arrhythmic, and genetic features of the disease as major and minor criteria has been maintained. In this modification of the Task Force criteria, quantitative criteria are proposed and abnormalities are defined on the basis of comparison with normal subject data. Conclusions The present modifications of the Task Force Criteria represent a working framework to improve the diagnosis and management of this condition. Clinical Trial Registration clinicaltrials.gov Identifier: NCT00024505.

Ground water and climate change

Abstract: As the world's largest distributed store of fresh water, ground water plays a central part in sustaining ecosystems and enabling human adaptation to climate variability and change. The strategic importance of ground water for global water and food security will probably intensify under climate change as more frequent and intense climate extremes (droughts and floods) increase variability in precipitation, soil moisture and surface water. Here we critically review recent research assessing the impacts of climate on ground water through natural and human-induced processes as well as through groundwater-driven feedbacks on the climate system. Furthermore, we examine the possible opportunities and challenges of using and sustaining groundwater resources in climate adaptation strategies, and highlight the lack of groundwater observations, which, at present, limits our understanding of the dynamic relationship between ground water and climate.

Mass-loss predictions for O and B stars as a function of metallicity

Abstract: We have calculated a grid of massive star wind models and mass-loss rates for a wide range of metal abundances between 1/100 and 10 Z/Zsun. The calculation of this grid completes the Vink et al. (2000) mass-loss recipe with an additional parameter Z. We have found that the exponent of the power law dependence of mass loss vs. metallicity is constant in the range between 1/30 and 3 Z/Zsun. The mass-loss rate scales as Mdot \propto Z^0.85 Vinf^p with p = -1.23 for stars with Teff \ga 25000 K, and p = -1.60 for the B supergiants with Teff \la 25000 K. Taking also into account the metallicity dependence of Vinf, using the power law dependence Vinf \propto Z^0.13 from Leitherer et al. (1992), the overall result of mass loss as a function of metallicity can be represented by Mdot \propto Z^0.69 for stars with Teff \ga 25000 K, and Mdot \propto Z^0.64 for B supergiants with Teff \la 25000 K. Our mass-loss predictions are successful in explaining the observed mass-loss rates for Galactic and Small Magellanic Cloud O-type stars, as well as in predicting the observed Galactic bi-stability jump. Hence, we believe that our predictions are reliable and suggest that our mass-loss recipe be used in future evolutionary calculations of massive stars at different metal abundance. A computer routine to calculate mass loss is publicly available.