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Institution

Vanderbilt University

EducationNashville, Tennessee, United States
About: Vanderbilt University is a education organization based out in Nashville, Tennessee, United States. It is known for research contribution in the topics: Population & Cancer. The organization has 45066 authors who have published 106528 publications receiving 5435039 citations. The organization is also known as: Vandy.


Papers
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Journal ArticleDOI
TL;DR: A consensus document is presented that proposes a standardized case definition and diagnostic guidelines for evaluation of adults and children with suspected encephalitis and will serve as a practical aid to clinicians evaluating patients with suspectedEncephalitis.
Abstract: Background Encephalitis continues to result in substantial morbidity and mortality worldwide. Advances in diagnosis and management have been limited, in part, by a lack of consensus on case definitions, standardized diagnostic approaches, and priorities for research. Methods In March 2012, the International Encephalitis Consortium, a committee begun in 2010 with members worldwide, held a meeting in Atlanta to discuss recent advances in encephalitis and to set priorities for future study. Results We present a consensus document that proposes a standardized case definition and diagnostic guidelines for evaluation of adults and children with suspected encephalitis. In addition, areas of research priority, including host genetics and selected emerging infections, are discussed. Conclusions We anticipate that this document, representing a synthesis of our discussions and supported by literature, will serve as a practical aid to clinicians evaluating patients with suspected encephalitis and will identify key areas and approaches to advance our knowledge of encephalitis.

740 citations

Journal ArticleDOI
TL;DR: The author revealed that the structure of the brain’s “habitats” changed over time as the child grew up, and the role of language and self-consistency in this process changed too.
Abstract: CONTENTS INTRODucnON 559 Mental Processes in Social Behavior 560 SOCIAL-INFORMA nON-PROCESSING THEORY . ... . . . . . . . . . . . .. . .. . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . 560 Application to Single Behavioral Events 562 Application to Child Psychopathology 563 Critique ..... ... . . . . . . . . . . . . . . . . . . . . .. 571 KNOWLEDGE STRUCTURES THAT GUIDE PROCESSING 573 Relation to Aggressive Behavior 575 Relation to Depression .. ... 577 DEVELOPMENTAL PSYCHOPATHOLOGY OF CONDUCT DISORDER AND DEPRESSION '''''''''''' 578 CONCLUSION 580

740 citations

Journal Article
TL;DR: This Perspective was written to highlight some of the existing literature on the aspirin-inhibitable branch of the arachidonic acid cascade and cancer, to apply that liter ature to colon cancer where possible, and to identify deficien cies in knowledge that need to be addressed.
Abstract: The arachidonic acid cascade generates a family of bioactive lipids that modulate diverse physiological and pathophysiological responses. Although there has been a great deal of interest in the involvement of arachidonic acid metabolites in cancer, there is uncertainty about which metabolites are the most im portant and how they contribute to specific steps in cell trans formation, tumor growth, and metastasis (1-9). The complex ity of arachidonic acid metabolism is daunting to neophytes and the multiplicity of responses exerted by a single metabolite can be confusing to the cognoscenti. This has made it difficult to extrapolate results from animal experiments to human beings. A recent report from Thun et al. (10) and previous reports from Rune et al. (11) and Rosenberg et al. (12) suggest that aspirin intake may reduce colon cancer incidence (11, 12) and mortality (10) in the general population. Other studies from Paganini-Hill et al. (13, 14) do not support such an association. Aspirin is a relatively specific inhibitor of one branch of the arachidonic acid cascade and even though there is not universal agreement among these epidemiological investigations, their findings refocus attention on the role of arachidonic acid me tabolites in cancer. This Perspective was written to highlight some of the existing literature on the aspirin-inhibitable branch of the arachidonic acid cascade and cancer, to apply that liter ature to colon cancer where possible, and to identify deficien cies in our knowledge that need to be addressed. Although the major focus is the colon, the mechanistic concepts should be applicable to other organ sites. The Perspective begins with an overview of arachidonic acid metabolism, proceeds to a consideration of the biochemistry and molecular biology of the enzyme inhibited by aspirin, touches on the signal transduction pathways linked to arachi donic acid metabolism, and then considers mechanisms by which specific arachidonic acid metabolites participate in the carcinogenic process. The review is not meant to be compre hensive and apologies are made in advance to colleagues whose work is not highlighted or was inadvertantly omitted.

739 citations

Journal ArticleDOI
TL;DR: The authors examined the ability of a theoretical model to predict types and levels of parental involvement during the elementary and middle school years, including motivational beliefs about involvement, perceptions of invitations to involvement from others, and perceived life context variables.
Abstract: This study examined the ability of a theoretical model to predict types and levels of parental involvement during the elementary and middle school years. Predictor variables included parents' motivational beliefs about involvement, perceptions of invitations to involvement from others, and perceived life context variables. Analyses of responses from 853 parents of 1st- through 6th-grade students enrolled in an ethnically diverse metropolitan public school system in the mid-southern United States revealed that model constructs predicted significant portions of variance in parents' home- and school-based involvement even when controlling for family socioeconomic status. The predictive power of specific model constructs differed for elementary and middle school parents. Results are discussed in terms of research on parental involvement and school practice.

738 citations

Journal ArticleDOI
Florence M.G. Cavalli1, Marc Remke1, Marc Remke2, Marc Remke3, Ladislav Rampášek1, John Peacock1, David Shih1, Betty Luu1, Livia Garzia1, Jonathon Torchia1, Carolina Nor1, A. Sorana Morrissy1, Sameer Agnihotri4, Yuan Yao Thompson1, Claudia M. Kuzan-Fischer1, Hamza Farooq1, Keren Isaev5, Keren Isaev1, Craig Daniels1, Byung Kyu Cho6, Seung-Ki Kim6, Kyu-Chang Wang6, Ji Yeoun Lee6, Wiesława Grajkowska7, Marta Perek-Polnik7, Alexandre Vasiljevic, Cécile Faure-Conter, Anne Jouvet8, Caterina Giannini9, Amulya A. Nageswara Rao9, Kay Ka Wai Li10, Ho Keung Ng10, Charles G. Eberhart11, Ian F. Pollack4, Ronald L. Hamilton4, G. Yancey Gillespie12, James M. Olson13, James M. Olson14, Sarah Leary13, William A. Weiss15, Boleslaw Lach16, Boleslaw Lach17, Lola B. Chambless18, Reid C. Thompson18, Michael K. Cooper18, Rajeev Vibhakar19, Peter Hauser20, Marie Lise C. van Veelen21, Johan M. Kros21, Pim J. French21, Young Shin Ra22, Toshihiro Kumabe23, Enrique López-Aguilar24, Karel Zitterbart25, Jaroslav Sterba25, Gaetano Finocchiaro, Maura Massimino, Erwin G. Van Meir26, Satoru Osuka26, Tomoko Shofuda, Almos Klekner27, Massimo Zollo28, Jeffrey R. Leonard29, Joshua B. Rubin29, Nada Jabado30, Steffen Albrecht30, Steffen Albrecht31, Jaume Mora, Timothy E. Van Meter32, Shin Jung33, Andrew S. Moore34, Andrew R. Hallahan34, Jennifer A. Chan35, Daniela Pretti da Cunha Tirapelli36, Carlos Gilberto Carlotti36, Maryam Fouladi37, José Pimentel, Claudia C. Faria, Ali G. Saad38, Luca Massimi39, Linda M. Liau40, Helen Wheeler41, Hideo Nakamura42, Samer K. Elbabaa43, Mario Perezpeña-Diazconti, Fernando Chico Ponce de León, Shenandoah Robinson44, Michal Zapotocky1, Alvaro Lassaletta1, Annie Huang1, Cynthia Hawkins1, Uri Tabori1, Eric Bouffet1, Ute Bartels1, Peter B. Dirks1, James T. Rutka1, Gary D. Bader1, Jüri Reimand5, Jüri Reimand1, Anna Goldenberg1, Vijay Ramaswamy1, Michael D. Taylor1 
TL;DR: Similarity network fusion (SNF) applied to genome-wide DNA methylation and gene expression data across 763 primary samples identifies very homogeneous clusters of patients, supporting the presence of medulloblastoma subtypes.

737 citations


Authors

Showing all 45403 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
Meir J. Stampfer2771414283776
John Q. Trojanowski2261467213948
Robert M. Califf1961561167961
Matthew Meyerson194553243726
Scott M. Grundy187841231821
Tony Hunter175593124726
David R. Jacobs1651262113892
Donald E. Ingber164610100682
L. Joseph Melton16153197861
Ralph A. DeFronzo160759132993
David W. Bates1591239116698
Charles N. Serhan15872884810
David Cella1561258106402
Jay Hauser1552145132683
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023141
2022541
20215,134
20205,232
20194,883
20184,649