Vignan University

About: Vignan University is a education organization based out in Guntur, Andhra Pradesh, India. It is known for research contribution in the topics: Control theory & CMOS. The organization has 1138 authors who have published 1381 publications receiving 7798 citations.

On some common fixed point theorems with rational expressions over closed subset of a Hilbert space

Abstract: This article provides the existence and uniqueness of a common fixed point for a pair of self mappings, positive integer’s powers of a pair of self mapping and a sequence of self mappings over a closed subset of a Hilbert space satisfying various conditions involving rational expressions.

Performance Evaluation of Indirect Vector Controlled Induction Motor Sensorless Drive

Abstract: This paper presents a hybrid system controller, incorporating fuzzy controller with vector control method for induction motors. The vector-control method has been optimized by using both PI and fuzzy controllers. This combines the benefits of fuzzy logic controller and vector-control in a single system controller. High quality of the regulation process is achieved through utilization of the fuzzy logic controller, while stability of the system during transient processes and a wide range of operation are assured through application of the vector control. This paper also deals with the speed estimators for applications in sensor less induction motor drive with vector control. In the present work, Indirect vector controlled induction motor sensor less drive with PI and Fuzzy controllers is implemented. It shows that the performance is better for fuzzy when compare to PI controller.

2-Aminoaryl-3,5-diaryl pyrazines: Synthesis, biological evaluation against Mycobacterium tuberculosis and docking studies.

Abstract: Rationally designed Mycobacterium tuberculosis (Mtb) inhibitors were synthesized under Buchwald conditions using Pd2 (dba)3 /xantphos and the compounds were investigated for their biological activity against the Mtb standard strain H37Rv and two other clinically isolated multidrug-resistant strains with different drug resistance patterns. Compounds 5e, 6e, 7e, and 8e exhibited excellent antituberculosis activity against H37Rv with a minimum inhibitory concentration (MIC) value of 15 μg/ml. Compounds 5a, 6c, 7b, 8a, 8b, and 8d also displayed their potency with a MIC value in the range of 15-25 μg/ml. In addition to the Mtb studies, compounds 4e, 5e, 7e, and 8e were tested for cytotoxicity on HEK-293 cells and compounds 7e and 8e were identified to have low toxicities of up to 200 and 300 μM, respectively. The synthesized compounds docked with the 2FUM protein of Mtb and the docking studies revealed that compounds 5e, 6e, 7e, and 8e can bind strongly in the active site of the enzyme and showed binding energies of -9.62, -10.7, -11.48, and -12.06 kcal/mol, respectively. Compound 7e forms four hydrogen bonds, whereas compound 8e forms five hydrogen bonds with amino acids, respectively. Based on these results, compounds 7e and 8e might be considered potential lead compounds with good anti-Mtb potency.