Vignan University

About: Vignan University is a education organization based out in Guntur, Andhra Pradesh, India. It is known for research contribution in the topics: Computer science & Control theory. The organization has 1138 authors who have published 1381 publications receiving 7798 citations.

Development of supercritical fluid (carbon dioxide) based ultra performance convergence chromatographic stability indicating assay method for the determination of clofarabine in injection

Abstract: The present study reports the development and validation of a stability indicating assay method for clofarabine in injection on a UPC2™ (ultra performance convergence chromatography) instrument, which utilizes the unrealized potential of supercritical fluid chromatography. The use of UPC2™ provides a single viable technique that is a sustainable, reduced cost, and green technology that lowers the use of organic solvents. Based on this advantage, we explored a simple and robust method in order to increase sample throughput and productivity to quantify clofarabine in the presence of its potential impurities and other degradants. The separation was achieved on a BEH-2-ethyl pyridine (BEH 2EP) column (100 mm × 3.0 mm I.D. with an average pore diameter of 1.7 μm) by using methanol as a co-solvent and carbon dioxide as a mobile phase in the ratio of 30:70. The detection is carried out at a wavelength of 254 nm. We are able to achieve the separation of clofarabine from its potential impurities and other degradants in less than 6 minutes with a low amount of solvent consumption. The new method is validated in accordance with the ICH-guidelines and exhibited good intra- and inter-day precision, accuracy and linearity (r2 ≥ 0.999) over a range of 50% to 150% of target concentration.

A Dense I1O3 Hybrid Superhydrophobic Network, Pb(H-BTMB), Exhibits Selectivity toward CO2 Gas Sorption

Abstract: We achieved a dense I1O3 hybrid superhydrophobic porous coordination polymer (PCP), [Pb(H-BTMB)(DMF)] (1), by solvothermal methods. The single-crystal XRD structure of 1 indicated that it has a three-dimensional M–L–M framework with one-dimensional M–O–M connectivity leading to an I1O3 network. The new PCP obtained exhibited open metal sites (OMSs) by losing a coordinated DMF molecule. The degassed phase displayed selective adsorption of CO2 gas over N2, C2H6, and C2H4 gases. Additionally, it has a superhydrophobic surface with a contact angle of 156.4° at room temperature and it is stable even at 90 °C, displaying a contact angle of 135.3°.

Enhanced energy storage performance of nanocrystalline Sm-doped CoFe2O4 as an effective anode material for Li-ion battery applications

Abstract: A simple modified combustion method was demonstrated in the development of cobalt ferrite (CoFe2O4) and samarium (Sm)-doped CoFe2O4 nanostructures. The Sm3+-doped CoFe2O4 can significantly affect their crystallite size, lattice parameter, and electrical and electrochemical properties. The powder X-ray diffraction analysis revealed the formation of cubic spinel CoFe2O4. The structural coordination of pristine and Sm3+-doped CoFe2O4 samples was confirmed by Raman and Fourier transform infrared spectroscopy analyses and also peak positions of Sm3+-doped CoFe2O4 sample shifted toward lower wavenumber, which may be due to the cell expansion resulting from Sm3+ doping in CoFe2O4 structure. In addition to above, X-ray photoelectron spectroscopy results clearly demonstrated the doping of Sm3+ into CoFe2O4 crystal lattice. The electrical conductivity of Sm3+-doped CoFe2O4 is one order of magnitude higher than that of pristine CoF2O4. The prepared pristine and Sm3+-doped CoFe2O4 samples were investigated as an anode material for lithium (Li)-ion batteries. The Sm3+-doped CoFe2O4 anode showed a better reversibility and rate performance than the pristine CoFe2O4 anode. Also, the Sm3+-doped CoFe2O4 electrode exhibited a stable cycling performance with a discharge capacity of 800 mAh g−1 after 150 cycles at 0.1 C and delivered a discharge capacity of 778 mAh g−1 after 400 cycles at 200 mA g−1. The observed high electrochemical performance of Sm3+-doped CoFe2O4 electrode may be attributed to its improved structural stability and enhanced oxidation reaction which maintain the number of Li ions involved in the charge-discharge process.

A study on scalability of services and privacy issues in cloud computing

Abstract: Cloud Computing is rapidly emerging and the new development in Information Technology. There are many patterns, or categories, in the world of cloud computing that are needed for the enterprise architecture. Some of the categories of services are storage, database, information, process, application, platform, integration, security, privacy, management/governance, testing, and infrastructure. Scalability is one of the important features applied on any of the services. The existing analysis specially focuses on Architectural and policy Implications without exploring the data privacy issues. In this paper, the application scalability and data privacy initiatives on various services in cloud environments are presented, with an overview of the trends they follow.