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Institution

Virginia Commonwealth University

EducationRichmond, Virginia, United States
About: Virginia Commonwealth University is a education organization based out in Richmond, Virginia, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 23822 authors who have published 49587 publications receiving 1787046 citations. The organization is also known as: VCU.


Papers
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Journal ArticleDOI
TL;DR: A brief motivational intervention to reduce the risk of an alcohol-exposed pregnancy (AEP) in preconceptional women by focusing on both risk drinking and ineffective contraception use can reduce therisk of an AEP.

282 citations

Journal ArticleDOI
TL;DR: Early SRT at low PSA levels after RP is associated with improved freedom from biochemical failure and distant metastases rates, and on multivariable analysis, pre-SRT PSA, GS, EPE, SVI, surgical margins, ADT use, and SRT dose were associated with FFBF.
Abstract: PurposeWe aimed to update a previously published, multi-institutional nomogram of outcomes for salvage radiotherapy (SRT) following radical prostatectomy (RP) for prostate cancer, including patients treated in the contemporary era.MethodsIndividual data from node-negative patients with a detectable post-RP prostate-specific antigen (PSA) treated with SRT with or without concurrent androgen-deprivation therapy (ADT) were obtained from 10 academic institutions. Freedom from biochemical failure (FFBF) and distant metastases (DM) rates were estimated, and predictive nomograms were generated.ResultsOverall, 2,460 patients with a median follow-up of 5 years were included; 599 patients (24%) had a Gleason score (GS) ≤ 6, 1,387 (56%) had a GS of 7, 244 (10%) had a GS of 8, and 230 (9%) had a GS of 9 to 10. There were 1,370 patients (56%) with extraprostatic extension (EPE), 452 (18%) with seminal vesicle invasion (SVI), 1,434 (58%) with positive surgical margins, and 390 (16%) who received ADT (median, 6 months)....

281 citations

Journal ArticleDOI
TL;DR: Previous HE and cognitive dysfunction are associated with worse employment, financial status, and caregiver burden and a multidisciplinary approach is required.

281 citations

Journal ArticleDOI
TL;DR: This work reports an AMPK-independent mechanism of mTORC1 inhibition by Sestrins mediated by their interaction with GATOR2, which is potentially involved in m TORC1 regulation by amino acids, rotenone, and tunicamycin, connecting stress response with mTORc1 inhibition.

281 citations

Journal ArticleDOI
TL;DR: An expert panel convened by the National Lipid Association to evaluate the use of selected biomarkers to improve risk assessment, or to adjust therapy is described, intended to provide practical advice to clinicians who wrestle with the challenges of identifying the patients who are most likely to benefit from therapy.

281 citations


Authors

Showing all 24085 results

NameH-indexPapersCitations
Ronald C. Kessler2741332328983
Carlo M. Croce1981135189007
Nicholas G. Martin1921770161952
Michael Rutter188676151592
Kenneth S. Kendler1771327142251
Bernhard O. Palsson14783185051
Thomas J. Smith1401775113919
Ming T. Tsuang14088573865
Patrick F. Sullivan13359492298
Martin B. Keller13154165069
Michael E. Thase13192375995
Benjamin F. Cravatt13166661932
Jian Zhou128300791402
Rena R. Wing12864967360
Linda R. Watkins12751956454
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
202395
2022395
20213,658
20203,437
20193,039
20182,758