Institution
Virginia Commonwealth University
Education•Richmond, Virginia, United States•
About: Virginia Commonwealth University is a education organization based out in Richmond, Virginia, United States. It is known for research contribution in the topics: Population & Health care. The organization has 23822 authors who have published 49587 publications receiving 1787046 citations. The organization is also known as: VCU.
Topics: Population, Health care, Poison control, Medicine, Cancer
Papers published on a yearly basis
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TL;DR: This phase 2 trial involving patients with NASH showed that treatment with semaglutide resulted in a significantly higher percentage of patients withNASH resolution than placebo, however, the trial did not show a significant between-group difference in the percentage of Patients with an improvement in fibrosis stage.
Abstract: Background Nonalcoholic steatohepatitis (NASH) is a common disease that is associated with increased morbidity and mortality, but treatment options are limited. The efficacy and safety of ...
651 citations
German Cancer Research Center1, Heidelberg University2, St. Jude Children's Research Hospital3, University of Toronto4, Ontario Institute for Cancer Research5, Institute of Cancer Research6, University of California, San Francisco7, Cincinnati Children's Hospital Medical Center8, Sapienza University of Rome9, University of Warsaw10, Boston Children's Hospital11, University of Bonn12, University of Hamburg13, Medical University of Vienna14, French Institute of Health and Medical Research15, Karolinska Institutet16, University of Freiburg17, Cork University Hospital18, Hadassah Medical Center19, Otto-von-Guericke University Magdeburg20, Copenhagen University Hospital21, Vanderbilt University Medical Center22, Children's Hospital of Philadelphia23, Washington University in St. Louis24, University of Göttingen25, Augsburg College26, University of Münster27, Radboud University Nijmegen28, VU University Medical Center29, University Medical Center Freiburg30, Ludwig Maximilian University of Munich31, University of Tübingen32, University of Basel33, Masaryk University34, University of Cambridge35, University of Amsterdam36, Necker-Enfants Malades Hospital37, Institut Gustave Roussy38, Aix-Marseille University39, University of Düsseldorf40, Virginia Commonwealth University41, University of Würzburg42, New York University43, Henry Ford Hospital44, University of Texas MD Anderson Cancer Center45, University of Queensland46, McGill University47
TL;DR: It is demonstrated that a significant proportion of institutionally diagnosed CNS-PNETs display molecular profiles indistinguishable from those of various other well-defined CNS tumor entities, facilitating diagnosis and appropriate therapy for patients with these tumors.
648 citations
TL;DR: Analgesia produced by focal electrical stimulation of the brain is partially reversed by the narcotic antagonist naloxone and it is suggested that stimulation-produced analgesia may result, at least in part, from release of an endogenous, narcotic-like substance.
Abstract: Analgesia produced by focal electrical stimulation of the brain is partially reversed by the narcotic antagonist naloxone. The absence of complete reversal does not appear to be caused by inadequate doses of naloxone since doses higher than 1 milligram per kilogram of body weight did not increase the antagonism. It is suggested that stimulation-produced analgesia may result, at least in part, from release of an endogenous, narcotic-like substance, such as that recently reported by other investigators.
647 citations
Kaiser Permanente1, University of California, San Francisco2, University of Iowa3, Harvard University4, Columbia University5, University of Pennsylvania6, Virginia Tech7, Duke University8, Virginia Commonwealth University9, Yale University10, University of Alabama at Birmingham11, University of California, Los Angeles12, Brown University13, Boston University14, Northwestern University15, University of Hawaii16
TL;DR: It is concluded with moderate certainty that screening for obesity in children and adolescents 6 years and older is of moderate net benefit and clinicians should offer or refer them to comprehensive, intensive behavioral interventions to promote improvements in weight status.
Abstract: Importance Based on year 2000 Centers for Disease Control and Prevention growth charts, approximately 17% of children and adolescents aged 2 to 19 years in the United States have obesity, and almost 32% of children and adolescents are overweight or have obesity. Obesity in children and adolescents is associated with morbidity such as mental health and psychological issues, asthma, obstructive sleep apnea, orthopedic problems, and adverse cardiovascular and metabolic outcomes (eg, high blood pressure, abnormal lipid levels, and insulin resistance). Children and adolescents may also experience teasing and bullying behaviors based on their weight. Obesity in childhood and adolescence may continue into adulthood and lead to adverse cardiovascular outcomes or other obesity-related morbidity, such as type 2 diabetes. Subpopulation Considerations Although the overall rate of child and adolescent obesity has stabilized over the last decade after increasing steadily for 3 decades, obesity rates continue to increase in certain populations, such as African American girls and Hispanic boys. These racial/ethnic differences in obesity prevalence are likely a result of both genetic and nongenetic factors (eg, socioeconomic status, intake of sugar-sweetened beverages and fast food, and having a television in the bedroom). Objective To update the 2010 US Preventive Services Task Force (USPSTF) recommendation on screening for obesity in children 6 years and older. Evidence Review The USPSTF reviewed the evidence on screening for obesity in children and adolescents and the benefits and harms of weight management interventions. Findings Comprehensive, intensive behavioral interventions (≥26 contact hours) in children and adolescents 6 years and older who have obesity can result in improvements in weight status for up to 12 months; there is inadequate evidence regarding the effectiveness of less intensive interventions. The harms of behavioral interventions can be bounded as small to none, and the harms of screening are minimal. Therefore, the USPSTF concluded with moderate certainty that screening for obesity in children and adolescents 6 years and older is of moderate net benefit. Conclusions and Recommendation The USPSTF recommends that clinicians screen for obesity in children and adolescents 6 years and older and offer or refer them to comprehensive, intensive behavioral interventions to promote improvements in weight status. (B recommendation)
646 citations
TL;DR: This article summarizes the consensus arrived at a meeting of the American Association for the Study of Liver Diseases on the key endpoints and specific trial design issues that are germane for development of diagnostic biomarkers and treatment trials for NASH.
646 citations
Authors
Showing all 24085 results
| Name | H-index | Papers | Citations |
|---|---|---|---|
| Ronald C. Kessler | 274 | 1332 | 328983 |
| Carlo M. Croce | 198 | 1135 | 189007 |
| Nicholas G. Martin | 192 | 1770 | 161952 |
| Michael Rutter | 188 | 676 | 151592 |
| Kenneth S. Kendler | 177 | 1327 | 142251 |
| Bernhard O. Palsson | 147 | 831 | 85051 |
| Thomas J. Smith | 140 | 1775 | 113919 |
| Ming T. Tsuang | 140 | 885 | 73865 |
| Patrick F. Sullivan | 133 | 594 | 92298 |
| Martin B. Keller | 131 | 541 | 65069 |
| Michael E. Thase | 131 | 923 | 75995 |
| Benjamin F. Cravatt | 131 | 666 | 61932 |
| Jian Zhou | 128 | 3007 | 91402 |
| Rena R. Wing | 128 | 649 | 67360 |
| Linda R. Watkins | 127 | 519 | 56454 |