Waseda University

About: Waseda University is a education organization based out in Tokyo, Japan. It is known for research contribution in the topics: Large Hadron Collider & Catalysis. The organization has 24220 authors who have published 46859 publications receiving 837855 citations. The organization is also known as: Waseda daigaku & Sōdai.

Feature selection and activity recognition from wearable sensors

Abstract: We describe our data collection and results on activity recognition with wearable, coin-sized sensor devices. The devices were attached to four different parts of the body: right thigh and wrist, left wrist and to a necklace on 13 different testees. In this experiment, data was from 17 daily life examples from male and female subjects. Features were calculated from triaxial accelerometer and heart rate data within different sized time windows. The best features were selected with forward-backward sequential search algorithm. Interestingly, acceleration mean values from the necklace were selected as important features. Two classifiers (multilayer perceptrons and kNN classifiers) were tested for activity recognition, and the best result (90.61 % aggregate recognition rate for 4-fold cross validation) was achieved with a kNN classifier.

Synthesis of nanoporous carbon-cobalt-oxide hybrid electrocatalysts by thermal conversion of metal-organic frameworks.

Abstract: Nanoporous carbon-cobalt-oxide hybrid materials are prepared by a simple, two-step, thermal conversion of a cobalt-based metal-organic framework (zeolitic imidazolate framework-9, ZIF-9). ZIF-9 is carbonized in an inert atmosphere to form nanoporous carbon-metallic-cobalt materials, followed by the subsequent thermal oxidation in air, yielding nanoporous carbon-cobalt-oxide hybrids. The resulting hybrid materials are evaluated as electrocatalysts for the oxygen-reduction reaction (ORR) and the oxygen-evolution reaction (OER) in a KOH electrolyte solution. The hybrid materials exhibit similar catalytic activity in the ORR to the benchmark, commercial, Pt/carbon black catalyst, and show better catalytic activity for the OER than the Pt-based catalyst.

Atmospheric neutrino flux calculation using the NRLMSISE-00 atmospheric model

Abstract: We extend our calculation of the atmospheric neutrino fluxes to polar and tropical regions. It is well known that the air density profiles in the polar and the tropical regions are different from the mid-latitude region. Also there are large seasonal variations in the polar region. In this extension, we use the NRLMSISE-00 global atmospheric model J. M. Picone, J. Geophys. Res. 107, SIA 15 (2002), replacing the U.S.-standard 1976 atmospheric model, which has no positional or seasonal variations. With the NRLMSISE-00 atmospheric model, we study the atmospheric neutrino flux at the polar and tropical regions with seasonal variations. The geomagnetic model international geomagnetic reference field (IGRF) we have used in our calculations seems accurate enough in the polar regions also. However, the polar and the equatorial regions are the two extremes in the IGRF model, and the magnetic field configurations are largely different from one another. Note that the equatorial region is also the tropical region generally. We study the effect of the geomagnetic field on the atmospheric neutrino flux in these extreme regions.

Midrapidity Neutral-Pion Production in Proton-Proton Collisions at √s = 200 GeV

Abstract: The invariant differential cross section for inclusive neutral-pion production in p+p collisions at roots=200 GeV has been measured at midrapidity (eta<0.35) over the range 1

Inhibition of ischaemic hippocampal neuronal death in primates with cathepsin B inhibitor CA‐074: a novel strategy for neuroprotection based on ‘calpain–cathepsin hypothesis’

Abstract: Although Cornu Ammonis (CA) 1 neurons of the hippocampus are known to be vulnerable to transient ischaemia, the mechanism of ischaemic neuronal death is still unknown, and there are very few strategies to prevent neuronal death at present. In a previous report we demonstrated micro-calpain activation at the disrupted lysosomal membrane of postischaemic CA1 neurons in the monkey undergoing a complete 20 min whole brain ischaemia. Using the same experimental paradigm, we observed that the enzyme activity of the lysosomal protease cathepsin B increased throughout the hippocampus on days 3-5 after the transient ischaemia. Furthermore, by immunocytochemistry cathepsin B showed presence of extralysosomal immunoreactivity with specific localization to the cytoplasm of CA1 neurons and the neuropil of the vulnerable CA1 sector. When a specific inhibitor of cathepsin B, the epoxysuccinyl peptide CA-074 (C18H29N3O6) was intravenously administered immediately after the ischaemic insult, approximately 67% of CA1 neurons were saved from delayed neuronal death on day 5 in eight monkeys undergoing 20 min brain ischaemia: the extent of inhibition was excellent in three of eight and good in five of eight monkeys. The surviving neurons rescued by blockade of lysosomal activity, showed mild central chromatolysis and were associated with the decreased immunoreactivity for cathepsin B. These observations indicate that calpain-induced cathepsin B release is crucial for the development of the ischaemic neuronal death, and that a specific inhibitor of cathepsin B is of potential therapeutic utility in ischaemic injuries to the human CNS.